济南治疗男性性功能阳痿(济南急性尿道感染怎么办) (今日更新中)

WASHINGTON, April 6 (Xinhua) -- A study led by researchers at the University of Michigan (U-M) showed in animal studies that new cancer drug compounds they developed shrank tumors, with few side effects.The study, done in two mouse models of human cancer, looked at two compounds designed to activate a protein that kills cancer cells. The protein, p53, is inactivated in a significant number of human cancers. In some cases, it is because another protein, MDM2, binds to p53 and blocks its tumor suppresser function. This allows the tumor to grow unchecked. The new compounds block MDM2 from binding to p53, consequently activating p53."For the first time, we showed that activation of p53 by our highly potent and optimized MDM2 inhibitors can achieve complete tumor regression in a mouse model of human cancer," says lead study author Shaomeng Wang, director of the Cancer Drug Discovery Program at the U-M Comprehensive Cancer Center.Wang presented the study Wednesday at the American Association for Cancer Research 102nd annual meeting.Many traditional cancer drugs also activate p53 but they do so by causing DNA damage in both tumor cells and normal cells, causing side effects. These new MDM2 inhibitors activate p53 while avoiding the DNA damage common with other drugs. In this study, which was done in collaboration with Ascenta Therapeutics and Sanonfi-Aventis, researchers showed that these new drugs shrank tumors without significant side effects.Because p53 is involved in all types of human cancer, the new drug has potential to be used in multiple types of cancer. Further, the researchers also identified certain markers in tumors that predict which ones will be particularly sensitive to the MDM2 inhibitor, which would allow physicians to target the drug only to patients most likely to benefit.

BEIJING, Feb. 19 (Xinhua) -- Chinese Vice Premier Li Keqiang has demanded the comprehensive enforcement of the country's food safety laws, urging checks to be tightened against unsafe food products.China should enhance efforts to ensure food safety, which is crucial for protecting human lives and improving people's living standards, Li said while addressing a meeting on food safety on Friday, according to an official statement issued Saturday.Also, emphasis should be directed to both special campaigns, which are launched to check against unsafe food, as well as daily supervision of food manufacturers, he said.The meeting also heard reports on food safety delivered by officials from health and agriculture ministries, the State Administration for Industry and Commerce, and the General Administration of Quality Supervision, Inspection and Quarantine.Participants at the meeting agreed that China should improve its system to monitor and assess food safety risks and enhance emergency response capabilities in this regard.They also called for improvement of food safety-related laws and regulations, as well as measures to target those core factors that affect the safety of food products.At the meeting, local government departments were asked to closely cooperate and improve the system to ensure food safety.Further, the participants agreed that authorities should publicize accurate information about food safety in a timely manner, and do more to forge a social atmosphere favorable for ensuring food safety.

UNITED NATIONS, Jan. 26 (Xinhua) -- China on Wednesday welcomed the smooth development of the south Sudan referendum, voicing its hope that the parties in south and north Sudan could reach a consensus at an early date on the outstanding issues through dialogue and consultations.Li Baodong, the Chinese permanent representative to the United Nations, made the statement in an interview with Xinhua after he spoke at the UN Security Council about the Chinese stance on the situation of Sudan.Earlier on Wednesday, the Security Council met to hear briefings from Atul Khare, UN assistant secretary-general for peacekeeping operations, and Ibrahim Gambari, the joint special representative of the African Union-United Nations Mission in Darfur (UNAMID), on the current situation in Sudan."China welcomes the smooth development of the south Sudan referendum, this is the result of the joint efforts of north and south Sudan and the international community," Li said."At present, priority should be given to the following work: First, continuous efforts should be made to fully maintain peace and stability in Sudan to enable the country to realize its long- term peace, stability and development," he said. "Second, efforts should be made to encourage the parties in south and north Sudan to continue their efforts for the full implementation of the Comprehensive Peace Agreement (CPA), particularly for a consensus at an early date on the outstanding issues."The referendum, with its week-long polling period ending on Jan. 15, will determine whether south Sudan remains a part of Sudan or becomes independent, in accordance with the 2005 CPA that ended a long-running north-south civil war.The referendum's preliminary results are expected to be announced by Feb. 2, and depending on whether appeals are launched in the courts, the final result will be declared on Feb. 7 or 14.

HARARE, Feb. 9 (Xinhua) -- The two-day visit to Zimbabwe by Chinese Foreign Minister Yang Jiechi starting Thursday is an endorsement of relations between the Southern African country and China, local figures told Xinhua.Former Zimbabwean ambassador to China Chris Mutsvangwa said in an interview on Tuesday that Yang's visit will also boost economic relations between the two countries."The visit of a foreign minister is a big banner announcement to say that relations between Zimbabwe and China are reaching for a new level," he said."This is a visit which will mark a new diplomatic high watermark in Zimbabwe's international relations because to get the visit of an important and emerging super-power like China with such economic clout is a big vote of confidence on the part of Zimbabweans who have been pummeled by sanctions" imposed by the West.Yang, who will make the visit at the invitation of Zimbabwean Foreign Minister Simbarashe Mumbengegwi, is scheduled to meet President Robert Mugabe and other senior government officials.Mutsvangwa said the Chinese veto at the United Nations in 2008 was "a landmark diplomatic decision where it basically saved Zimbabwe from punitive sanctions instigated by an irate and sulky former colonial power.""So, now this visit will give an opportunity for Zimbabweans tofinally thank China for this act. But more important, cooperation in the economic field is beginning to gather pace because we have crossed the diplomatic and political travails which have been going on in the last 10 years and come out more united because the Chinese veto also enabled Zimbabweans to find accommodation among themselves and led to the GNU and GPA," Mutsvangwa said.China, together with Russia, vetoed the British initiative for full-scale UN sanctions against Zimbabwe, saying the Southern African Development Community (SADC) and the African Union (AU) should be given a chance to resolve the country's political problems.A SADC-driven initiative led to a Government of National Unity (GNU) following the signing of the Global Political Agreement (GPA) between Mugabe and then rivals Prime Minister Morgan Tsvangirai and Deputy Prime Minister Arthur Mutambara."So there is more national unity now among Zimbabweans. It is an opportune moment for us to tighten our relations with China so that we can explore cooperation in the more rewarding material areas of agriculture, mining, tourism and industrialization."There is clearly a lot of scope for cooperation between Zimbabwe and China so that Zimbabwe can quicken its modernization pace taking advantage of the stellar achievements of the Chinese in the above areas," Mutsvangwa said.He cited areas such as telecommunications, international logistics and the internet as being led by the Chinese.China Tobacco has also been on the fore-front reviving tobacco farming in Zimbabwe for the past five years.Mutsvangwa said shortages in the global cotton sector could spur better trade relations between the two countries and lead to more opportunities for Zimbabwean farmers.

来源：资阳报