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Former UN Secretary-General and Nobel Peace Prize winner Kofi Annan has died at age 80, his foundation confirmed Saturday.Annan, who was born in Ghana in 1938, served as the seventh UN Secretary-General, from 1997 to 2006, and was the first to rise from within the ranks of the United Nations staff.He had also been a member, since 2007, of The Elders, a humanitarian group of a dozen leaders and activists of worldwide stature formed by Nelson Mandela. In 2013, Annan became its chairman.The Kofi Annan Foundation confirmed his death with "immense sadness" in a statement posted on Twitter.Annan passed away peacefully Saturday morning after a short illness, with his wife Nane and their three children by his side during his final days, the statement said. 766

For the first time in more than a decade, a new treatment to improve brain function for Alzheimer’s disease has been submitted to the Food and Drug Administration (FDA) for review.This was after the drug trial was stopped and then a second look revealed some promising results.The Waterhouse family has seen the impact of Alzheimer’s firsthand.Gina and Steve Waterhouse have been a team most of their lives. They’ve been married for 43 years and ran several businesses together. Then in 2016, things started to change. Gina didn’t notice anything but employees at the family's businesses did.“I wasn't remembering some of the stuff I was supposed to be doing,” said Gina.Gina was diagnosed with early Alzheimer's disease that year.“They said, 'well you can come back in a year. We will check and see how you're doing, or we have a drug trial if you're interested,'” said Gina.Gina and Steve spent the next two and a half years at the Mayo Clinic, where Gina eventually got high doses of the drug aducanumab.Steve started to notice Gina was remembering more things and reported it back to doctors.“He just smiled and said, 'let me tell you what we're seeing. We're seeing cognitive improvement. And it’s the first time in my career.' These doctors said in their career that we've ever seen it,” said Steve.“He was so excited,” said Gina.Then in 2019, the drug trial suddenly ended. Gina says she felt like she’s gone downhill a little since it did.Rebecca Edelmeyer, PhD, with the Alzheimer’s Association, says the trial stopped early based on a futility analysis.“It was a statistical analysis that was done by the Biogen team, predicting that the trial would not actually be successful,” said Edelmeyer.Edelmeyer says then upon a second look at the trial data, they found that those people on the highest dose of the drug were seeing improvement in their brain function. She called it a very important moment for the Alzheimer’s research community.Now, the government will determine whether or not the drug is safe and effective enough to use.Steve mentioned there were some possible side effects like bleeding of the brain, but Gina did not experience any.Meanwhile, Gina can no longer take the drug. She and Steve have decided to retire.“We just decided tomorrow has to come today and we're having a great time. We're loving life,” said Gina.You can learn more about aducanumab here. 2394

Former Vice President Joe Biden canceled a planned appearance in Illinois this week because he is sick and "under doctor's orders not to travel," according to state Democrats."Everyone who knows Vice President Biden knows that he gives our party and our country his all, but unfortunately he is sick and is under doctor's orders not to travel," Illinois Democratic County Chairs' Association President Doug House said in a statement posted to Facebook Tuesday night.Biden, 75, was scheduled as a keynote speaker for the Illinois Democrats County Chairs' Association brunch in Springfield, Illinois. The event kicks off Democrats' Day at the Illinois State Fair."The cancellation is of course disappointing, but it is clear that the circumstances are simply unavoidable," House said.House added, "We all hope he gets well soon and I'm sure he'll be back campaigning for Democrats in Illinois and across the country in no time."A spokesman for Biden said the former vice president is simply under the weather and will "be fine in a few days." The spokesman would not comment on the record about Biden's condition.Biden has been crisscrossing the country campaigning with Democrats candidates ahead of the midterm elections but also fueling speculation that he'll seek the Democratic presidential nomination in 2020. 1321

FLORIDA — Kratom is a natural plant native to Southeast Asia that has been used in the region for decades, but it's fairly new to the United States.Some people say it's helped them in reducing pain and has helped addicts recover. But others say it's dangerous and could even be deadly. Experts said it's been linked to deadly overdoses. The Drug Enforcement Administration (DEA) identified 15 deaths connected to Kratom from 2014 to 2016. The FDA records at least 44 Kratom related deaths in the last decade. One of these deaths is 27-year-old Christopher Waldron. His mother, Laura Lamon says he was her only son and the love of her life.  On July 17th, 2017 she got a call from Tampa police. “He [investigator] said your son is deceased. I lost it. I just started yelling and I don't remember much after that,” Lamon said. Lamon thought that he had overdosed on narcotics, but a month later she received an autopsy report that indicated the cause of death was intoxication by Kratom, and strictly Kratom, according to the Hillsborough medical examiner. "I was shocked and then when I got it. I thought, 'What is this?' I had found some things in his room and I saw the packages of what he had taken but I didn't know much about it,” Lamon said. Director of SalusCare Steven Hill says one of the biggest dangers with Kratom is that it’s not regulated or monitored. “You never know exactly what you're getting. Anything could be in the packaging. There could be different levels of the active substance,” Hill said. Lamon believes that if the plant was properly labeled, her son would have survived. “There was no label on it at all. it didn't have a dosage amount, didn't have a warning label, didn't say don't mix it with this or that, if you have this condition, or whatever. a bottle of Tylenol has that on there,” Lamon said. She says that it is so devastating because her son didn’t want to die. She doesn't necessarily want to see Kratom banned, but thinks it should be researched and much more regulated.“It absolutely should be banned, it’s like playing a game of roulette,” Steven Hill, director of SalusCare, said. Adrianna Marrone, manager of Up in Smoke in the Cape says Kratom came to the U.S. recently, and now it’s one of their best sellers. “Just to help with the aches and pains and anxiety and depression,” Marrone said. A former addict, Amanda Raska, says that Kratom helped her overcome drugs. “He told me about Kratom and that day I tried and I never touched another pill, it literally saved my life,” Rasksa said. Raska said she started using Kratom five months ago when a friend who was also an addict told her about it. Before using the plant, she couldn't get out of bed without taking prescription pills. “It was a horrible life, I have 5 kids so i could not even take care of my children,” Raska said. She said that she grew up around addicts and has an addictive personality, but said Kratom isn’t addicting. If she goes without it, there’s no symptoms of withdrawal.Steven Hill says that he saw firsthand how people react to the drug. “It’s happened on our detox where people are coming in and the issue is with Kratom,” Hill said. Hill said the experience of taking Kratom can be described as a quick down feeling followed by hallucinations and visualizations. In 2016, there were less than 100 poison control calls regarding the drug, and by the middle of 2018, the number of calls were approaching 700. “So we're seeing more and more use and we're seeing the health concerns and health issues also go up. ER visits spiked,” Hill said. In August 2016, the DEA announced an intent to ban Kratom, but after strong reaction from the public, it was labeled as pending analysis. “We've seen and heard of people who have very bad reactions. people who have had to be hospitalized,” Hill said.  3982

Forecasters have warned of potentially record-breaking temperatures in Spain and Portugal this week as much of Europe swelters in a heat wave that has left some farmers suffering drought conditions.The UK Met Office said parts of the Iberian peninsula could beat the all-time continental European record of 48 degrees Celsius (118.4 degrees Fahrenheit) this week, with inland areas likely to be hotter than the coast.That record was set in the Greek capital, Athens, in July 1977. According to the World Meteorological Organization, the record for Spain is currently 47.3 Celsius, while for Portugal it's 47.4 Celsius.The Portuguese capital, Lisbon, could see a high of 41 Celsius on Saturday, according to CNN forecasters. Its average temperature is 28 Celsius for this time of year.A heat wave warning was in place across much of southern and eastern France on Thursday. The national meteorological agency, Méteo France, said Wednesday that temperatures in the south of the country would come close to record highs in the coming days.Vacationers have been warned to take precautions against extreme temperatures, as the heat wave coincides with the peak holiday season in Europe.Vulnerable people such as children and the elderly could be at risk of heat stroke, which occurs when a person's core body temperature rises above 40 Celsius and can lead to permanent brain, heart and kidney damage and, in more severe instances, death.Spain's meteorological office, Aemet, warned of high temperatures lasting from Wednesday into early next week.The hot spell will be particularly intense and long-lasting in Spain's southwest, the central zone and the Ebro Valley, with temperatures above 40 Celsius, it said. In inland areas of the northwestern region of Galicia, normally known for its mild, rainy weather, the mercury could hit 41 Celsius on Thursday, it said.Wildfires have raged in Sweden and neighboring Scandinavian nations in recent weeks amid unusually hot, dry conditions. Some places in Sweden have had their driest May-to-July period on record, according to its meteorological agency, and a number of weather stations have recorded only 10% to 15% of their normal rainfall.The United Kingdom is also experiencing a prolonged spell of hot, dry weather. The Met Office said last week that some parts of east and southeast England had had virtually no rain for more than 50 days. Thunderstorms over the weekend brought with them rain and cooler weather, but temperatures are again on the rise.The National Farmers' Union hosted an emergency summit Wednesday with representatives of the UK government, at which it called for its members to be given help to cope with the conditions. Farmers are struggling with irrigation, heat stress on livestock, the loss of crops and a shortage of forage for animals, the union said."The impacts of the dry and hot weather have been hugely challenging for many farms across the country, with many not seeing such weather in their lifetimes," said NFU President Minette Batters.The UK Environment Agency said it would allow greater flexibility in the rules on water extraction to help farmers manage the situation.Meanwhile, German Agriculture Minister Julia Kl?ckner wrote to the European Commission on Wednesday urging it to take steps to help farmers affected by drought. Food for livestock could become scarce in the coming weeks, she warned.The past four months in Germany have been very hot and dry, particularly in the north and east of the country.The European Commission announced measures Thursday to help farmers cope, including giving them higher advance payments from EU funds and granting more flexibility to use land that would normally be left fallow to grow animal fodder.The latter measure will be of particular help to livestock farmers, it said. 3815