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New research suggests that antibodies the immune system makes to fight the new coronavirus may only last a few months in people with mild illness, but that doesn’t mean protection also is gone or that it won’t be possible to develop an effective vaccine.“Infection with this coronavirus does not necessarily generate lifetime immunity,” but antibodies are only part of the story, said Dr. Buddy Creech, an infectious disease specialist at Vanderbilt University. He had no role in the work, published Tuesday in the New England Journal of Medicine.The immune system remembers how to make fresh antibodies if needed and other parts of it also can mount an attack, he said.Antibodies are proteins that white blood cells called B cells make to bind to the virus and help eliminate it. The earliest ones are fairly crude but as infection goes on, the immune system becomes trained to focus its attack and to make more precise antibodies.Dr. Otto Yang and others at the University of California, Los Angeles, measured these more precise antibodies in 30 patients diagnosed with COVID-19 and four housemates presumed to have the disease. Their average age was 43 and most had mild symptoms.Researchers found that the antibodies had a half-life of 73 days, which means that half of them would be gone after that much time. It dovetails with a previous report from China also suggesting antibodies quickly fade.The results “call for caution regarding antibody-based ‘immunity passports,’ herd immunity, and perhaps vaccine durability,” the California authors write.That’s true, Creech said, but other parts of the immune system also help confer protection. Besides churning out antibodies, B cells develop a memory so they know how to do that again if needed.“They would get called into action very quickly when there’s a new exposure to the virus. It’s as if they lie dormant, just waiting,” he said.Other white blood cells called T cells also are better able to attack the virus the next time they see it, Creech said.Although circulating antibodies may not last long, what we need to know is if and how people remake antibodies if exposed to the coronavirus again and if they protect against another infection, Alison Criss, an immunologist at the University of Virginia, wrote in an email. “We also need to know if there is a protective T cell response” that reappears.Vaccines, which provoke the immune system to make antibodies, might give longer-lasting protection than natural infection because they use purified versions of what stimulates that response, she noted.Creech agreed.“This shouldn’t dissuade us from pursuing a vaccine,” he said. “Antibodies are only a part of the story.”___Marilynn Marchione can be followed on Twitter at http://twitter.com/MMarchioneAP___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 2967

New York State has issued guidance on professional sports competitions as part of Phase Four of the New York Forward program.The state says professional sports can resume in the state, but with no fans."Ensure that no live audience, fans, or spectators are allowed to attend or permitted to enter any professional sports venue, even if an outdoor venue. Prohibit fans from congregating outside the venue and implement a security plan to safely disperse any individuals that gather outside of the venue," the guidance states.Several guidelines will also be in place for team staff, athletes and venue personnel such as:Maintaining six feet of distance whenever possible.Wearing appropriate face coverings whenever possible.Limiting the use of frequently shared spaces.Limiting the number of individuals on site at a given time.Ensuring all team staff, athletes, and venue personnel receive training on COVID-19 safety, proper hand hygiene, and cleaning and disinfection protocols.Limiting the sharing of objects.Providing and maintaining hand hygiene stations.Conducting regular cleaning and disinfecting of the venue and equipment.No sharing of food or personal items.Diagnostic testing for COVID-19 for all athletes and essential team staff with regular player access 48 hours before a competition.Daily health screenings for anyone entering the venue.The state says this guidance does not apply to collegiate sports, horse racing or auto racing.This article was written by Anthony Reyes for WKBW. 1506

NEW YORK – New York’s attorney general is suing the National Rifle Association, seeking to put the powerful gun advocacy organization out of business over allegations that high-ranking executives diverted millions of dollars for personal benefit.The lawsuit filed Thursday by Attorney General Letitia James followed an 18-month investigation into the NRA, which is a nonprofit group originally chartered in New York.Watch the announcement below:The attorney general is accusing the NRA's top leaders of using the association's funds for lavish personal trips, contracts for associates and other questionable expenditures.James says the leadership’s failure to manage the NRA’s funds and failure to follow state and federal laws led the organization to lose more than million in just three years.In addition to shuttering the NRA’s doors, James is seeking to recoup millions in lost assets and to stop the four defendants in the case from serving on the board of any nonprofit in the state of New York again.Along with the NRA, the defendants in the suit are Executive Vice-President Wayne LaPierre, former Treasurer and Chief Financial Officer (CFO) Wilson “Woody” Phillips, former Chief of Staff and the Executive Director of General Operations Joshua Powell, and Corporate Secretary and General Counsel John Frazer.The lawsuit alleges that the four men instituted a culture of self-dealing, mismanagement, and negligent oversight at the NRA that was illegal, oppressive, and fraudulent.“The NRA’s influence has been so powerful that the organization went unchecked for decades while top executives funneled millions into their own pockets,” said James. “The NRA is fraught with fraud and abuse, which is why, today, we seek to dissolve the NRA, because no organization is above the law.” We are seeking to dissolve the NRA for years of self-dealing and illegal conduct that violate New York’s charities laws and undermine its own mission.The NRA diverted millions of dollars away from its charitable mission for personal use by senior leadership.— NY AG James (@NewYorkStateAG) August 6, 2020 In a statement, the president of the NRA called the lawsuit a "baseless" attack on the organization and the Second Amendment. 2232

NEWPORT, Wales — A 5-year-old girl in Newport, Wales, died just hours after a doctor refused to see her because she was late to her appointment, according to the BBC.The girl's mother, Shanice Clark, has been searching for answers since her daughter, Ellie-May, died from bronchial asthma in 2015, according to the New York Post. Thanks to a coroner’s inquest into her daughter's death, she was finally given some answers on Monday.The coroner ruled that Grange Clinic “missed” the opportunity to “provide potentially live-saving treatment” to her child, Sky News reports.The 5-year-old girl was reportedly not seen by a doctor, despite having an emergency appointment,  because it operated a "10-minute rule."Clark said she and her daughter arrived only five minutes late because they didn't have a car. She said she warned them she might be late when she called the clinic. According to the coroner, this was the first time the rule had been enforced in regards to an emergency appointment. Reports also state that Clark was reportedly told to come back in the morning without the doctor even looking at her daughter’s medical records, which would have shown that the child has a history of asthma.“From the evidence before me, it is not possible for me to determine with certainty whether an earlier intervention would have altered the outcome for Ellie, but nonetheless Ellie should have been seen by a [doctor] that day, and she was let down by the failures in the system,” the coroner wrote.According to the New York Post, Grange Clinic released a statement, saying: “Dr. Rowe knows that nothing can be said to Ellie-May’s family to make a difference, but she would like to say how truly sorry she is.”The coroner plans to write a letter to the health board and the clinic in hopes of addressing the tragedy and preventing similar situations in the future. Additionally, a spokesman for Aneurin Bevan University Health Board told BBC it would be "inappropriate to comment whilst we await the coroner's report".Mary Stringini is a Digital Reporter for ABC Action News. Follow her on Twitter @MaryWFTS. 2209

NEW YORK (AP) — Professional networking company LinkedIn is laying off nearly 1,000 employees, or approximately 6% of its global workforce, as a slowdown in hiring amid the coronavirus pandemic pressures its business. In a note to employees, CEO Ryan Roslansky said that the positions that will be eliminated are in its global sales and hiring offices. Roslansky said it's the only layoffs LinkedIn is planning. "To continue adapting and accelerating the company as we have been, we need to ensure we are focusing our efforts and resources against our most strategic priorities to set up the company for success today—and well into the future," Roslansky said in the letter. "When we took a hard look at the business, we decided we needed to make some hard calls."Roslansky said 960 roles across their Global Sales and Talent Acquisition organizations would be eliminated.Impacted U.S. employees will receive at least 10 weeks of severance pay and a year of continuing health coverage through COBRA. LinkedIn will also provide immigration support, career transition assistance, and the option to keep company cell phones, laptops, and other recently purchased equipment for departing employees to be able to work from home.Those being laid off will continue in their roles through Aug. 21.LinkedIn is owned by Microsoft. 1328