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Could the no-calorie sweetener you rely on to replace sugar in your diet actually cause weight gain instead of the weight loss you were expecting?The answer may be yes, according to a new study."Artificial sweeteners are not risk-free," said Brian Hoffmann, assistant professor in the Department of Biomedical Engineering at the Medical College of Wisconsin and Marquette University, and a lead author of the study. "They are a very controversial topic when it comes to health and nutrition ... but they're so prevalent in society that I think we owe it to ourselves to try and figure out what's actually going on."Hoffmann presented his new research Sunday at the annual?Experimental Biology meeting in San Diego. Relying on rats and human cell cultures, his team identified a number of pathways linking artificial sweeteners with metabolic changes at the genetic level that could lead to diabetes and obesity. Specifically, the researchers found that three weeks of exposure to aspartame and acesulfame potassium -- two artificial sweeteners frequently combined in products such as Equal -- altered the expression of certain genes responsible for lipid metabolism in the cells of both rats and humans."Aspartame had some significant changes, and one of those was an increase in lipids in the bloodstream and a decrease in a biomolecule that is involved in clearing (lipids) from the bloodstream. And we saw the exact same thing with the acesulfame potassium," Hoffmann said."We then took those particular sweeteners and put them on endothelial cells -- the cells that line the blood vessels and would be exposed to them in the body -- and we detected a marked dysfunction, suggesting why sweeteners and diet soda have been linked to potential cardiovascular problems," he added.What was perhaps most surprising, according to Hoffmann, was that these metabolic changes did not occur in the presence of natural sugars such as glucose and fructose. This suggests that artificial sweeteners could contribute to metabolic disorders such as diabetes and obesity by an entirely different mechanism than natural sugars, he said.Artificial sweeteners appear to contribute to metabolic disorders by altering the activity of certain genes responsible for the breakdown of macromolecules such as fats and proteins, Hoffmann said. This is different from normal sugars, which contribute to cardiovascular disease through insulin resistance and by damaging the cells lining the body's blood vessels."People are generally consuming non-nutritive sweeteners believing they are a 'healthy choice,' but this may not be true," said research scientist Meghan Azad of the University of Manitoba in Winnipeg, who was not involved in the new study."This is especially important given the widespread and increasing consumption of artificial sweeteners in the general population and the increasing use of artificial sweeteners in our food supply," said Azad, who has authored a paper that reviewed a number of studies on the potential downside of artificial sweeteners on weight and health.According to Azad, over 40% of adult Americans consume no-cal sweeteners on a daily basis, and studies that measure the sweeteners in blood and urine show that many people who report not using artificial sweeteners are unknowingly consuming them.It's the latest assault in the ongoing debate over artificial sweeteners and their impact on health -- a debate that began when one of our most popular foods, sugar, turned sour in terms of health. 3527

CLAY COUNTY, Tennessee — Three people were shot Monday morning at a residence in Clay County, Tennessee, where a school bus driver pulled up to the scene and provided aid.The incident was reported at a home on Crabtree Creek Road and North Fork Road in Whitleyville. A school bus driver called 9-1-1 after he or she pulled up to a stop and realized there had been an incident in the home. Initial reports indicated that the shooting happened on a school bus. However, Clay County School officials confirmed the incident did not happen on the bus. The bus driver gave aid to at least one person in the home.  At least two of the victims were airlifted to Nashville for treatment. A third person was transported by ambulance. 756

CORONADO, Calif. (KGTV) -- The owner of The Coronado Flower Lady, a popular flower stand along Orange Avenue, is trying to rebuild after a suspected drunk driver destroyed her business. Coronado police say 22-year-old Elias Atayee is being charged with felony DUI after crashing his car into the stand. They say Atayee also had a female passenger inside his car. RELATED: Driver slams into Coronado pole, picnic tables“The fact that there are people drinking and driving, going 90-100 miles per hour, I have my kids out here with me all the time at work," owner Shanel Albert said. "There are tons of kids out here and people. If one of my girls would have been here during the day and that happened, they would have been dead. And that scares me.” Thanks to the City of Coronado, Albert will be back selling her flowers on a table in the same spot until she can permanently rebuild her stand. A GoFundMe has been set up to help with costs and Albert says she hopes people will choose to place their orders through her since her business is still operational.   1104

COMPILED BY California Department of Social ServicesSEARCH FOR YOUR FACILITY ONLINECommunity Care Licensing Division has compiled important information regarding licensed facilities to provide the public on an online searchable database. The information supplied on the database contains facility inspection reports, violations, inspection history and other pertinent information for prospective parents/caregivers.SEARCH LICENSED FACILITIESThis information should serve as an initial point of inquiry regarding the status of licensed facilities. Additional information about a particular facility is available from the appropriate licensing office.If your child is already enrolled in licensed care, you can subscribe to your child's facility in the database and get updates when any new information is provided about that facility.Regarding Family Child Care Homes in the Facility Database:Large family child care homes may be searched by area and contain the same information child care centers have excluding addresses.Small family child care homes may only be searched by knowing the exact facility license number; a general search will not bring up the small family child care home.Family child care homes located in Del Norte or Inyo County are not in the database.Your local Resource and Referral Agency (R&R), is also available to help you find a child care facility.CHOOSING THE BEST CHILD CARE FOR YOUR FAMILYThe Parent’s Guide to Choosing Child Care is the Department’s comprehensive publication for parents seeking child care. It includes information about the different types of child care that are licensed in California, various educational philosophies, questions to ask a prospective provider, and a checklist to take with you when you tour facilities while making your child care decision. Also available in Spanish. 1843

CINCINNNATI, Ohio — Federal officials have arrested one of the alleged masterminds behind a moving company scam accused of ripping off more than 900 people across the country, including more than 100 in the Ohio, Indiana and Kentucky tri-state region.Now that Serghei Verlan is in the Butler County, Ohio jail, one of his alleged victims talked to WCPO television station in Cincinnati, saying the scam was very costly to her.“Anytime a mover asks you for money up front, run,” advised Jeanne Porter.Porter said she and her husband Mike ended paying more than ,400 after hiring Flagship Van Lines to move them from Ohio to Florida. She said they had to wait and wait and wait for their stuff to arrive.“It never came … We were sitting here in Florida with no furniture in our house for about three weeks,” Porter said. 828