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WASHINGTON, June 6 (Xinhua) -- Women who have higher levels of the appetite-controlling hormone leptin have fewer symptoms of depression, and this apparent inverse relationship is not related to body mass index (BMI), a new study finds. The results were presented Monday at The Endocrine Society's 93rd Annual Meeting in Boston, the United States."Animal data suggest that leptin may reduce anxiety and improve depression. Our study in women suggests that leptin may indeed have antidepressant qualities," said the study's lead author, Elizabeth Lawson, of Massachusetts General Hospital and Harvard Medical School in Boston.Leptin, the product of fat cells, signals satiety, or fullness. It is low in thin women and high in obese women, according to Lawson. She also said there is an increased prevalence of anxiety and depression in certain conditions in which leptin levels are typically low. These include the eating disorder anorexia nervosa, in which there is abnormally low weight and body fat, and functional hypothalamic amenorrhea, in which women have stopped menstruating despite having normal weight."It is unknown whether low leptin levels contribute to the development of mood disorders in these women," Lawson said.She and her co-workers studied the relationship between leptin levels and symptoms of anxiety and depression in 64 women. Fifteen of the women had anorexia nervosa, 12 were normal weight with hypothalamic amenorrhea, 20 were normal weight and in good health, and 17 were overweight or obese but still healthy.All subjects were asked questions to assess symptoms of depression and anxiety, with high scores indicating more symptoms. Besides measuring leptin levels in the blood, the researchers assessed the women's BMI, a measure of weight for height.The relationship between leptin and depression symptoms was independent of BMI. This finding indicates that leptin may mediate symptoms of depression and that this effect is not a function of low weight, Lawson said."Further research administering leptin to humans will be important in understanding whether this hormone has a potential role in the treatment of depression," she said.

BEIJING, Aug. 31 (Xinhuanet) – The pressure of modern society is taking a toll on sexual satisfaction, experts say following the release of an online survey.About 34 percent of people polled in the survey said that they are unsatisfied with their sex lives, with 6.5 percent "very unsatisfied".Another 32 percent condemned their sex lives as "just so-so".The survey interviewed more than 3,000 people, aged between 15 and 55, with men accounting for 74 percent of the interviewees.It was conducted by the China Population Communication Center and the Shanghai Academy of Social Sciences from May 1 to June 20. The survey did not give a margin of error.Only 23 percent of respondents said that they are "satisfied" with their sex lives, with 3.6 percent "very satisfied", according to the survey.But women seem to have a higher rate of satisfaction than men, with only 26 percent saying they are unsatisfied. The rate for men is 42 percent.The rate of sexual satisfaction among Chinese people is below the global average of 44 percent, according to an earlier survey by Durex. The 2007 Durex Global Sexual Wellbeing Survey questioned more than 26,000 people in 26 countries about all aspects of their sex lives - including satisfaction levels.Jiang Hui, president-elect of the Chinese Society of Andrology, attributed the lower rate of sexual satisfaction among Chinese people to rapid economic growth, which inevitably increases work and social pressure.Health problems associated with a modern lifestyle, such as diabetes and hypertension, are also to blame, he said.Jiang said his department of andrology used to receive about 10 patients a day 10 years ago. Now the figure has risen to more than 250.Rising awareness of sex and a more open attitude toward the once-taboo topic among the public also contributed to higher sexual expectations, he said.The survey also revealed that about 30 percent of respondents in the 35-55 age group had sex less than once a week."That rate is quite low, compared with the global average of 103 times a year, or 1.98 times a week," said Yang Xiong, who heads the social survey center at the Shanghai Academy of Social Sciences.Only 16.9 percent of respondents said that they had sex more than 10 times a month. Most respondents had sex three to nine times every month.About 8 percent of respondents said that they basically had no sex at all or it was too infrequent to be classified.The survey seemed to find that the more you made, the less you had. Those who earned at least 9,000 yuan (,400) a month had less sex than those who earned less, according to the survey.Among those making more than 9,000 yuan per month, over 70 percent said they had sex less than twice a month, compared with 16.5 percent for those with a monthly salary of less than 6,000 yuan.The survey also found that when people run into problems with their sex lives, 83 percent turn to the Internet, rather than professionals, for help. Less than 6 percent said they would see doctors to solve sex-related problems.Nearly 70 percent of those polled said they suffered from sexual health problems, such as erectile dysfunction (ED)."Many patients, especially men, are reluctant to see a doctor, which they think harms their manhood," Jiang said.According to a study conducted by the Chinese Society of Andrology, at least 40 percent of men aged 40 and above suffered from erectile dysfunction, roughly the global average.But Yang, from the Shanghai academy, noted that surveys conducted online tend to produce far different results than those conducted face-to-face.He expressed reservations about the survey's accuracy and said the public should only use the results for reference.

WASHINGTON, Aug. 2 (Xinhua) -- The weakness of aging is associated with leaky calcium channels inside muscle cells and a drug already in Phase II clinical trials for the treatment of heart failure might plug those leaks, according to a report published Tuesday in the online edition of Cell Metabolism.Earlier studies by the research team led by Andrew Marks of Columbia University showed the same leaks underlie the weakness and fatigue that come with heart failure and Duchenne muscular dystrophy."It's interesting, normal people essentially acquire a form of muscular dystrophy with age," Marks said. "The basis for muscle weakness is the same." Extreme exercise like that done by marathon runners also springs the same sort of leaks, he added, but in that case damaged muscles return to normal after a few days of rest. A microscopic view shows smooth muscle cells derived from human embryonic stem cells showing the nuclei (blue) and proteins of the cytoskeleton (green) in this handout photo released to Reuters by the California Institute for Regenerative Medicine, March 9, 2009The leaks occur in a calcium release channel called ryanodine receptor 1 (RyR1) that is required for muscles to contract. Under conditions of stress, those channels are chemically modified and lose a stabilizing subunit known as calstabin1.Calcium inside of muscle cells is usually kept contained. When it is allowed to leak out into the cell that calcium itself is toxic, turning on an enzyme that chews up muscle cells. Once the leak starts, it's a vicious cycle. The calcium leak raises levels of damaging reactive oxygen species, which oxidize RyR1 and worsen the leak.The researchers made their discovery by studying the skeletal muscles of young and old mice. They also showed that 6-month-old mice carrying a mutation that made their RyR1 channels leaky showed the same muscular defects and weakness characteristic of older mice.When older mice were treated with a drug known as S107, the calcium leak in their muscles slowed and the animals voluntarily showed about a 50 percent increase in the amount of time spent wheel running. Now in clinical trials for patients with heart failure, the drug is known to work by restoring the connection between costabilin and RyR1.Despite considerable effort to understand and reverse age- related muscle wasting, there are no established treatments available. The new work suggests there may be hope in approaching the problem from a different angle."Most research has focused on making more muscle mass," Marks said. "What's different here is that we are focused not on muscle mass but on muscle function. More muscle doesn't help if it is not functional."

BEIJING, July 19 (Xinhuanet) -- Amazon on Monday launched its Kindle textbook rental service, which allows students to rent "tens of thousands of textbooks", according to Los Angeles Times.The e-book textbook rental service will help students save as much as 80 percent on some titles.Amazon said that students can now rent textbooks from 30 to 360 days and can either rent them again or purchase them once the rental period is up."Students tell us that they enjoy the low prices we offer on new and used print textbooks. Now we're excited to offer students an option to rent Kindle textbooks and only pay for the time they need—with savings up to 80 percent off the print list price on a 30-day rental," Dave Limp, vice president of Amazon Kindle said, according to PC Magazine.Rentals can be read on Amazon's Kindle eReaders, and Kindle apps for PCs, as well as smartphones and tablet computers running Apple's iOS, Microsoft Windows Phone 7 and Google's Android operating system.Rentals also have a clear advantage over physical copies that students' notes and highlighted content will be stored in the Amazon Cloud, and can be accessed if students rent the books again or buy at a later time.

WELLINGTON, June 10 (Xinhua) -- Scientists have uncovered an almost complete picture of the remains of a geological formation that was one of the great wonders of the 19th Century world before it was covered in ash and water during a volcanic eruption.Scientists from New Zealand and the United States said Friday they had discovered the White Terraces, half of the famous Pink and White Terraces in the central North Island's Lake Rotomahana.The same group of scientists found the remnants of the pink half of the former world-famous tourist attraction on the lake floor in January.The Pink and White Terraces were buried by the eruption of Mount Tarawera 125 years ago on 10 June 1886. The two sets of cascading silica terraces were separated by several hundred metres.The two formerly glistening terraces were formed on the shores of the lake, where the silica rich waters were warmed by the magma beneath.In the late 19th Century, the cascading terraces attracted people from all over the world. The White Terraces were the larger and stretched to a height of 30 meters, forming a 240-meter face. Visitors could walk up to a crater platform where they could bathe in the clear blue waters in naturally-formed basins up to three meters deep.Project Leader Cornel de Ronde, of New Zealand's GNS Science geosciences research institute, said the sonar images from Lake Rotomahana showed the lake floor was covered overwhelmingly by soft sediment and mud.The side-scan sonar data of the lake floor was collected on the last day of the 10-day project at Lake Rotomahana during the southern summer, but was analyzed using new software, which became available after the data collection had finished.The scientists found the sonar data contained images of hard, crescent-shaped structures on the lake bed in a similar location to where the White Terraces were before the eruption of 1886.The structures were about 60 meters below the surface, a similar depth to the Pink Terraces found in January. The lake is about 122 meters deep at its deepest point."The two places on the lake floor where we encountered hard, up- standing crescent-shaped features correspond to the locations of the Pink and White Terraces before the Tarawera eruption," de Ronde said."The sonar image that appears to show part of the White Terraces came to light after the project had finished. It shows a horizontal segment of terraces over 100 meters long, although we don't know which part of the terraces it is."The rounded terrace edges are standing up from the lake floor by about a meter in some places. The sonar images of both sets of terraces are strikingly similar."Scientists managed to capture several color photographs of part of the Pink Terraces in January, but they did not lower an underwater camera over the White Terraces location during the project as they were unaware of what the sonar data was showing at the time.The fate of the remaining sections of the Pink and White Terraces was unclear, said a statement from GNS. "They might have been destroyed in the eruption. Alternatively, they could be lying under thick sediment, which is impenetrable to sonar signals sent out by the two autonomous underwater vehicles (AUVs) used in the survey."De Ronde said finding remnants of both sets of terraces was a remarkable outcome for the project."The project team was absolutely thrilled in January when we realised our AUVs had detected remnants of the Pink Terraces. Finding part of what we believe is the White Terraces as well has been surprising and very satisfying."The original aim of the project at Lake Rotomahana was to map the lake floor and investigate the extensive geothermal system under the lake and how it evolved from an on-land geothermal system to a submerged one. Anything else was a bonus," de Ronde said."It's gratifying to be part of a science project that can answer a century-old mystery about the fate of the Pink and White Terraces."De Ronde said the announcement of the find was timed to coincide with the 125th anniversary of Tarawera's eruption.The 10-day project was a collaboration involving GNS Science, Woods Hole Oceanographic Institution in Massachusetts, Lamont- Doherty Earth Observatory at Columbia University in New York, the National Oceanic and Atmospheric Administration in Seattle, and New Zealand's University of Waikato.