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U.S. government officials are putting an early end to a study testing an Eli Lilly antibody drug for people hospitalized with COVID-19 because it doesn’t seem to be helping them.Independent monitors had paused enrollment in the study two weeks ago because of a possible safety issue. But on Monday, the National Institute of Allergy and Infectious Diseases, which sponsors the study, said a closer look did not verify a safety problem but found a low chance that the drug would prove helpful for hospitalized patients.It is a setback for one of the most promising treatment approaches for COVID-19. President Donald Trump received a similar experimental, two-antibody drug from Regeneron Pharmaceuticals Inc. on an emergency basis when he was sickened with the coronavirus earlier this month.In a statement Lilly notes that the government is continuing a separate study testing the antibody drug in mild to moderately ill patients, to try to prevent hospitalization and severe illness. The company also is continuing its own studies testing the drug, which is being developed with the Canadian company AbCellera.Antibodies are proteins the body makes when an infection occurs; they attach to a virus and help it be eliminated. The experimental drugs are concentrated versions of one or two specific antibodies that worked best against the coronavirus in lab and animal tests.Lilly and Regeneron have asked the U.S. Food and Drug Administration to grant emergency use authorization for their drugs for COVID-19 while late-stage studies continue. Lilly says its request is based on other results suggesting the drug helps patients who are not hospitalized, and that it will continue to seek the FDA’s permission for emergency use.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 1928
Tuesday night, it was a who's who of A-list celebrities, all taking part in the Hand in Hand benefit to help people impacted by hurricanes Harvey and Irma. In total, the even raised more than 44 million dollars, but it may take much more to help victims fully recover.Nearly three weeks after Hurricane Harvey and you see debris and destroyed furniture in many Houston neighborhoods. At the Tyty home, recovery is a slow process, with some bright spots making it a little easier."Fortunately our stove is currently working," says Tosha Atibu. "It can still work."Atibu's home is gutted out, still she, her husband and four children are still living in it."I know it's not a safe place to be but I don't know where else I can go," Atibu says.More than 20,000 people are still in shelters or FEMA hotels in Texas. And even though flood waters are gone, mold and mosquitoes are still here along with the threat of sickness and disease. In hard-hit Port Arthur and Beaumont, people are still struggling to find the basics like food and water.But right now, all eyes are focused on Florida where people are just beginning picking up the pieces left in Irma's wake. They're clearing debris from roads and checking for damage, so that those who evacuated can return to their homes. But millions are still without power and boil water advisories are in place in many areas.In the U.S. Virgin Islands people are still being evacuated to Puerto Rico.St. Thomas Evacuee Patrice Harris says, "Being in a state where I'm not sure what's going to happen next, not sure where I'm gonna get my next meal, that's something that's very discomforting for me. So I'm happy to have been able to leave the island."All said, this is going to be a long recovery. The latest estimates show together, hurricanes Harvey and Irma have caused between 150 billion and 200 billion dollars in damage. And one estimate puts that figure closer to 300 billion dollars. 1972

UPS has reportedly told its drivers to stop picking up packages from several national retailers as they try to keep up with record-breaking online shopping this holiday season.Online shopping has seen record highs in 2020, as people heed public safety warnings during the coronavirus pandemic and avoid shopping in person.The National Retail Federation estimates online shopping during the five-day period including Black Friday and Cyber Monday jumped 44 percent. Adobe Analytics estimates online shopping on Thanksgiving and Black Friday were both up 22 percent compared to last year, and that Black Friday was the highest-grossing online shopping day in history. An internal memo at UPS, obtained by the Wall Street Journal, indicates the company placed temporary shipping restrictions on retailers like Nike, Gap, Macy’s, L.L. Bean and others. The message reportedly tells drivers to stop picking up packages at some of these retailers for the time being."Knowing the unique constraints the industry is facing this peak season, we worked with our carriers early on to collectively build a strategic plan of execution," Gap said in a statement to CNN.A Nike spokesperson told media: "We expect the majority of these orders to meet estimated delivery dates and are communicating with consumers any changes in delivery."A UPS company spokesperson told the WSJ they will pick up packages who have exceeded allocated space once more capacity becomes available.UPS and rival FedEx have already raised prices for merchants and said they would hold merchants to shipping volume agreements.The United States Postal Service is also trying to manage the increase in packages, increasing pricing for companies and hiring thousands of temporary workers to handle the deliveries.For those wondering, here is a look at the 2020 holiday shipping deadlines per delivery company. 1874
VENTURA, Calif. (AP) — A California church held indoor worship service Sunday morning despite a judge’s temporary restraining order that bars the church from doing so. The pastor led a 9 a.m. service in defiance of coronavirus health orders at Godspeak Calvary Chapel in Ventura County’s Newbury Park. A livestream of the morning’s service showed a mask-less pastor and a musician standing before at least two dozen worshipers — most of whom were also not wearing masks. It was not clear from the livestream if they were standing 6 feet apart. Two other services are planned for later Sunday. 600
Two candidates endorsed by President Donald Trump are locked in tight races, with votes from Tuesday's elections still left to count.The special election in a deep-red Ohio congressional district was too close to call Tuesday night, with Republican Troy Balderson holding a narrow lead over Democrat Danny O'Connor.In the Republican primary in the Kansas governor's race, meanwhile, Trump-backed Secretary of State Kris Kobach and incumbent Gov. Jeff Colyer were waiting on results from the highly populated Johnson County, in the Kansas City area. 556
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