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When a vaccine is approved, who will get it? How will it get to them?Johns Hopkins has a plan to make front line workers and those most vulnerable first in line. Other experts say that may not be the best approach.“It may be better to immunize people who are at high risk of transmitting the virus both because of jobs, living situations and other circumstances,” said Dr. Ezekiel Emanuel while speaking with the head of the Journal of the American Medical Association. “And that I think we have to leave an open mind and look at some detailed modeling about what the best way is to reduce the premature mortality.”Emanuel says transmission between health care workers and patients is basically zero where he is. He says effective PPE use is the reason.The groups Johns Hopkins said should get a vaccine first could be as big as 90 million people.Emanuel says there won't be enough doses out of the gate to get all of any initial groups.“You don’t actually distribute it evenly among countries,” he said. “You concentrate on countries that at the moment when you have the vaccine have severe hot spots and where the vaccine is going to make the biggest difference in terms of reducing premature death.”Johns Hopkins experts say a vaccine's effectiveness is measured on preventing disease. That doesn't mean it prevents infection and transmission. We won’t know how effective it will be until after it’s in use.“A disease transmission strategy makes a lot of sense, but we need a lot more information before we can know who to prioritize,” said Dr. Eric Toner, a senior scholar at the Johns Hopkins Center for Health Security. “It’s quite possible we will go to a strategy like that.”The World Health Organization said younger people in their 20s, 30s and 40s are increasingly driving spread.The first vaccines will likely be two doses. Experts say that means double the syringes, needles, vials and other supplies, along with getting people to come back for a second dose. 1980
Winnie Madikizela-Mandela, the South African anti-apartheid activist and former wife of the late President Nelson Mandela, has died at the age of 81.The family said in a statement that she passed away at the Netcare Milpark Hospital in Johannesburg, South Africa after a long illness, for which she had been in and out of hospital since the start of the year. 367

With its low air pressure, Hurricane Michael unofficially sits as the third-strongest landfalling hurricane to strike the United States. Having such a tremendously low air pressure typically causes storms to have strong winds, and Michael was no exception. Hurricane Hunters from the Air Force and NOAA estimated Michael's lowest pressure was 919 MB at landfall. The only two hurricanes with a lower pressure at landfall to hit the United States were the Labor Day Hurricane of 1935 and Camille of 1969.Also based on estimates, Michael had top winds of 155 MPH, which is just below Category 5 status. Based on top winds speeds, Michael was tied for the sixth-strongest landfalling hurricane in US history, tied with Hurricane Maria in 2017 and "Guam" in 1900. In terms of air pressure, Michael was 1 MB stronger than Katrina in 2005 and Maria in 2017 at landfall, and 3 MBs stronger than Andrew of 1992. Michael's top winds at landfall were well ahead of Katrina's top winds at landfall of 130 MPH, on par with Maria's top winds at landfall of 155 MPH, but below Andrew's top winds of 165 MPH.But in the immediate aftermath of Andrew, it was declared a Category 4 hurricane at landfall. It was not until years later when the National Hurricane Center concluded that winds in Andrew were greater than 157 MPH, marking the only Category 5 hurricane to strike the US since Camille in 1969. Like Andrew, Michael continued to strengthen all the way until landfall. In just three days, the storm went from a tropical storm to a high-end Category 4 hurricane. Other reasons Micheal will be notable:- Michael was just the sixth hurricane of at least Category 4 strength to hit Florida since 1950. 1752
White House chief of staff John Kelly, under fire over the White House's handling of domestic abuse allegations against a senior aide, ordered an overhaul of the security clearance process for current and incoming top administration officials.In a five-page memo to the White House counsel, national security adviser and deputy chief of staff for operations, Kelly called for all background check investigations into potential top White House officials to be delivered directly to the White House Counsel's office by the FBI and for the FBI to share "significant derogatory information" uncovered in the course of investigations into senior staff with the White House within 48 hours, according to a copy of the memo released by the White House. 759
With lawsuits, recounts and protests all looming, here is the official timeline for reporting and certification of the 2018 General Election results from the Florida Department of State:November 6 204
来源:资阳报