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The Wake Forest Institute for Regenerative Medicine says it has a new use for its bioprinting system. In the past they've 3D printed normal-size organs and tissues in hopes of someday implanting them in patients.For the coronavirus, the lab is creating organs using human cells that can be as small as a pinhead. They're focusing on the organs most likely to be infected by the disease. like the lungs.“And so we've been playing with a number of agents to, on both prongs what can make it more infective, what can make it less infective to try to sort this out for the future,” Anthony Atala, director for the institute said.Atala says he hopes the system will help in testing drugs before they hit the market.Drug companies do extensive testing and clinical trials in people before releasing a new medication.Atala says sometimes those companies find no serious side effects, but then years later, discover that it's toxic to patients taking it. Atala says testing a drug using the bioprinting system can tell if a drug is toxic in weeks instead of after years on the market.“Even though we've used the tool extensively for toxicity testing, it's also a tool that can be used for screening,” Atala said. “So we can test agents that are currently being considered for testing against COVID and test the efficacy of the treatment on miniature human organs made up of normal cells”To be clear, Atala said drug tests on 3D printer organs are not meant to replace clinical trials in humans, be are an added step to better predict what will happen in those trials. 1567

The toy run in December is usually one of the big ways Children's Hospital Colorado gets donated toys. But because of COVID-19, the supply of toys is down considerably. So the hospital reached out to some riders, and Sunday, they got a special delivery to help replenish that supply.Kids at Children's Hospital know when they hear those Harley engines roar, toys are on the way."Any motorcycles coming up to the hospital, the kids plaster themselves the windows. They love to see the bikes riding up," volunteer Bob Cuculich said."That's why we do it. It's things like this that make it all worthwhile," organizer Eddie Dane said.But it's not December when this toy run usually happens."Because of COVID this year, the hospital reached out to Rocky Mountain Harley Davidson, because we're a sponsor to the toy run and have been for years," Dane said.Dozens of bikers answered the last minute call to help."They're not reusing toys. So we are are going to replenish their supply and do the best we can to get them some more toys to last them until December," Dane said.They didn't know how many bikers would show. They just knew they needed to try to help the kids."There's a huge need," Cuculich said.But the roars were there, filling up the bins, and they hope more toys can be brought. Just no stuffed animals right now."Plush toys right now, they are just too hard to keep clean, and infection control just makes it a challenge to be able to give those to the kids," Cuculich added.The bikers hope this special delivery makes the kids happy and lasts until the main ride in December. Just a little Christmas in July.KMGH's Sean Towle first reported this story. 1671

The U.S. again broke its daily record for new confirmed cases of COVID-19 on Wednesday, as local health departments recorded 50,000 new confirmed cases of the virus, according to a database kept by Johns Hopkins.The previous record was set Tuesday when health departments reported about 45,400 new cases.The figures highlight a continued spike in cases throughout the country over the past few weeks. Prior to the recent peak, the highest daily increase in confirmed cases came on April 24, when health departments reported about 36,400 new cases. The U.S. has recorded at least 38,900 new cases every day for the last week.(John's Hopkins)Because the Johns Hopkins database is reliant on reporting from local health departments, the data doesn't necessarily reflect a patient's day of infection. Daily case numbers are often higher mid-week because some local health departments or test centers may be closed on weekends.It's not just cases that are on the rise. According to the Institute for Health Metrics and Evaluation at the University of Washington, use of hospital beds, ICU beds and invasive ventilators have all risen in recent weeks after months of falling resource use.Many states have either "paused" or chosen to take steps back in their reopening process as cases and hospitalizations linked to the virus continue to rise.On Tuesday, Dr. Anthony Fauci — the government's top expert on infectious diseases — called the recent spike in cases "disturbing," and said that he could foresee the U.S. reporting up to 100,000 new COVID-19 cases a day if recent trends continue. 1593

The U.S. secretary of Commerce says the 2020 census will end Oct. 5, despite a federal judge’s ruling last week that the head count of every U.S. resident should continue through the end of October, according to a tweet posted on the Census Bureau’s website Monday. The tweet said the ability for people to self-respond to the census questionnaire and the door-knocking phase census takers go to homes that haven’t yet responded is ending Oct. 5. The announcement came as a virtual hearing was being held in San Jose, California, as a follow-up to U.S. District Judge Lucy Koh’s preliminary injunction.The Commerce Department says that as of September 20, 95.4 percent of all households have been enumerated.The decennial census is responsible for allocating congressional districts, Electoral College votes, and federal funds. 835

The United States Supreme Court is expected to rule on several major cases next week impacting everything from abortion rights to the presidential election. Traditionally, the court issues all of it's rulings by the end of June to go on recess by early July. It's unclear this year however if the Supreme Court will extend its rulings if they are behind because of the pandemic. The Supreme Court said in advance what days justices will issue opinions, but would not announce which specific opinions will be announced on those days. Rulings typically come down around 10 a.m. ET.EXPECTED CASE #1 SEPARATION OF CHURCH AND STATE CHANGES?In Espinoza v. Montana Department of Revenue, the ruling could allow students in religious schools the ability to seek private scholarships funded through state income-tax credits. For years such programs were thought to be incompatible with Montana's constitutional ban on public aid to religious schools, however the Supreme Court could allow the program to exist. Because similar bans exist in 38 states, the ruling could change the definition of the separation of church and state. EXPECTED CASE #2CHANGE TO ABORTION RIGHTS?In June Medical Services LLC v. Russo, the ruling could impact the future of abortion rights across the country. The ruling examines whether a Louisiana law, which requires abortion providers to have admitting privileges in nearby hospitals, is constitutional. Abortion-rights activists say it will lead to clinics being shut down because most providers don't work with hospitals. More importantly, the ruling could tell anti-abortion leaders across the country that the High Court may be open to changes to Roe v Wade in the future. EXPECTED CASE #3ELECTORAL COLLEGE CONFUSION?In Colorado Department of State v. Baca, the ruling could result in major confusion in the 2020 election. The case is out of Colorado where in 2016, state electors to the electoral college attempted to vote for someone other than the winner of Colorado, Hillary Clinton. The electors were removed and replaced with someone to deliver the actual result, however it raised questions over how much power do these electors really have. EXPECTED CASE #4PRESIDENT TRUMP TAX RETURNS?In Trump v. Mazars USA, LLP and Trump v. Deutsche Bank, the question is whether the president has to comply with subpoenas for personal records. Does the power of the presidency allow President Donald Trump to say "no" when it comes to revealing his tax returns? If the Supreme Court rules against President Trump, it could create a new controversy for the President ahead of the election. 2615