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BEIJING, Aug 4 (Xinhuanet) – A new urine test might help doctors detect prostate cancer and better evaluate a patient's treatment options, according to American reseachers Thursday."This is a tool that men and their physician can use to help them decide whether it's appropriate to get a biopsy now or delay that decision," said lead researcher Dr. Scott Tomlins, a pathology resident at the University of Michigan Health System.The test looks for two genetic markers associated with prostate cancer. The first, called TMPRSS2:ERG, is caused by two genes changing places and fusing together; it is thought to cause prostate cancer. Since the gene fusion is only seen in about half of cancer patients, the test also looks for another marker, called PCA3."We are exploiting some new bio-markers to try to refine the PSA (prostate-specific antigen) test," Tomlins said.

LOS ANGELES, July 18 (Xinhua) -- U.S. scientists have proven that oncogenes can change normal cells into stem-like cells, paving the way to a safer and more practical approach to treating diseases like multiple sclerosis and cancer with stem cell therapy.In a collaborative study, researchers from the Keck School of Medicine of the University of Southern California (USC), and the Children's Hospital of Orange County (CHOC) in California and Good Samaritan Hospital Medical Center in New York have successfully converted human skin cells into brain cells by suppressing the expression of p53, a protein encoded by a widely studied oncogene. This suggests that p53 mutation helps determine cell fate -- good or bad -- rather than only the outcome of cancer.Oncogenes are generally thought to be genes that, when mutated, change healthy cells into cancerous tumor cells.Study findings were appearing Monday on the website of the American Association for the Advancement of Science (AAAS)."The reality may be more complicated than people think," said Jiang F. Zhong, Ph.D., assistant professor of pathology at the Keck School. "What is a stem cell gene? What is a cancer gene? It may be the same thing.""When you turn off p53, people think the cell becomes cancerous because we tend to focus on the bad thing," Zhong said. "Actually, the cell becomes more plastic and could do good things, too. Let's say the cell is like a person who loses his job (the restriction of p53). He could become a criminal or he could find another job and have a positive effect on society. What pushes him one way or the other, we don't know because the environment is very complicated."Stem cells can divide and differentiate into different types of cells in the body. In humans, embryonic stem cells differentiate into three families, or germ layers, of cells. The reasons why and how certain stem cells differentiate into particular layers are not clearly understood. However, from those layers, tissues and organs develop. The endoderm, for example, leads to formation of the stomach, colon and lungs, while the mesoderm forms blood, bone and heart tissue. In its study, Zhong's team examined human skin cells, which are related to brain and neural cells from the ectoderm.When p53 was suppressed, the skin cells developed into cells that looked exactly like human embryonic stem cells. But, unlike other man-made stem cells that are "pluripotent" and can become any other cells in the body, these cells differentiated only into cells from the same germ layer, ectoderm."IPSCs (induced pluripotent stem cells) can turn into anything, so they are hard to control," Zhong said. "Our cells are staying within the ectoderm lineage."Zhong said he expects that suppressing other oncogenes in other families of cells would have the same effect, which could have critical significance for stem cell therapy. Future research should focus on determining which genes to manipulate, Zhong said.The study is slated to appear in the Proceedings of the National Academy of Sciences later this month, according to AAAS.

WASHINGTON, July 12 (Xinhua) -- Two U.S. astronauts stepped out the International Space Station on Tuesday to retrieve a failed ammonia pump, which is the last spacewalk of the shuttle era, NASA announced.Space station astronauts Mike Fossum and Ron Garan completed the six-hour, 31-minute spacewalk at 3:53 p.m. EDT (1953 GMT). The duo retrieved a pump module from an external stowage platform on station and store it in shuttle Atlantis' cargo bay for return to Earth.The pump module failed in 2010, shutting down half of the space station's cooling system. Engineers will evaluate the module to determine the cause of the failure and plan to refurbish it for use as a spare.The astronauts also attached a Robotic Refueling Module experiment to the space station, which aims to test technologies for repairing and refueling satellites in space.It was the 249th spacewalk by U.S. astronauts and the 160th spacewalk in support of space station assembly and maintenance, totaling 1009 hours, nine minutes.Atlantis lifted off on Friday morning from Kennedy Space Center in Florida, on the 135th and final flight in NASA's shuttle program. Its return to the earth later this month will mark the end of the 30-year shuttle program.

SEOUL, Aug. 31 (Xinhua) -- South Korea's infant mortality rate decreased by nearly half in the last 20 years to stand as the world's 16th lowest, a report showed Wednesday.South Korea had an infant mortality rate of 2.2 per 1,000 in 2009, compared with four deaths per 1,000 newborns reported in 1990, the World Health Organization (WHO) and Save the Children, an international non-governmental organization working for children's rights, said in a joint report.With a 45 percent decline in the infant mortality rate, South Korea ranked 16th lowest among WHO member countries, down from its 88th spot in 1990, according to the report. South Korea's infant mortality rate was the same as France, Estonia and Malta. Meanwhile, the Democratic People's Republic of Korea (DPRK) also showed a decline in the infant mortality rate from 23 per 1,000 in 1990 to 18.1 per 1,000 in 2009, but still remained in the lower ranks with 125th place.

WASHINGTON, Aug. 24 (Xinhua) -- Online search engine Google Inc. has agreed to pay 500 million U.S. dollars to settle claims that it allowed online Canadian pharmacies to place advertisements targeting consumers in the United States, U.S. Justice Department announced Wednesday.The settlement, one of the largest ever in the United States, represents the gross revenue received by Google as a result of Canadian pharmacies advertising through Google's AdWords program, plus gross revenue made by Canadian pharmacies from their sales to U.S. consumers.The advertisements led to illegal imports of prescription drugs into the country, the Justice Department said.The shipment of prescription drugs from pharmacies outside the United States to customers in the United States typically violates the Federal Food, Drug and Cosmetic Act and in the case of controlled prescription drugs, the Controlled Substances Act.Google was aware as early as 2003, that generally, it was illegal for pharmacies to ship controlled and non-controlled prescription drugs into the United States from Canada."The Department of Justice will continue to hold accountable companies who in their bid for profits violate federal law and put at risk the health and safety of American consumers," Deputy Attorney General James Cole said in a statement."This settlement ensures that Google will reform its improper advertising practices with regard to these pharmacies while paying one of the largest financial forfeiture penalties in history," he said.Google had previously set aside that amount for a possible settlement over its advertising practices, according to a regulatory filing in May.