济南前列腺增生 治疗医院(济南前列腺引起的早泄能治吗) (今日更新中)

Bulked-up, mutant “mighty mice” held onto their muscle during a monthlong stay at the International Space Station, returning to Earth with ripped bodybuilder physiques, scientists reported Monday.The findings hold promise for preventing muscle and bone loss in astronauts on prolonged space trips like Mars missions, as well as people on Earth who are confined to bed or need wheelchairs.A research team led by Dr. Se-Jin Lee of the Jackson Laboratory in Connecticut sent 40 young female black mice to the space station in December, launching aboard a SpaceX rocket.In a paper published in the Proceedings of the National Academy of Sciences, Lee said the 24 regular untreated mice lost considerable muscle and bone mass in weightlessness as expected — up to 18%.But the eight genetically engineered “mighty mice” launched with double the muscle maintained their bulk. Their muscles appeared to be comparable to similar “mighty mice” that stayed behind at NASA’s Kennedy Space Center.In addition, eight normal mice that received “mighty mouse” treatment in space returned to Earth with dramatically bigger muscles. The treatment involves blocking a pair of proteins that typically limit muscle mass.A SpaceX capsule brought all 40 mice back in good condition, parachuting into the Pacific off the California coast in January. Some of the ordinary mice were injected with the “mighty mice” drug after returning and quickly built up more muscle than their untreated companions, Lee said.The scientists completed the experiment just as the coronavirus was hitting the U.S.“The only silver lining of COVID is that we had time to write it up very intensively” and submit the results for publication, said Dr. Emily Germain-Lee of Connecticut Children’s Medical Center, Lee’s wife who also took part in the study. Both are affiliated with the University of Connecticut.While encouraged by their findings, the couple said much more work needs to be done before testing the drug on people to build up muscle and bone, without serious side effects.“We’re years away. But that’s how everything is when you go from mouse to human studies,” Germain-Lee said.Lee said the experiment pointed out other molecules and signaling pathways worth investigating — “an embarrassment of riches ... so many things we’d like to pursue.” His next step: possibly sending more “mighty mice” to the space station for an even longer stay.Three NASA astronauts looked after the space mice, performing body scans and injections: Christina Koch and Jessica Meir, who performed the first all-female spacewalk last fall, and Andrew Morgan. They are listed as co-authors.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 2835

CARLSBAD, Calif. (KGTV) - A motorcyclist from San Marcos died Sunday after crashing into a truck in Carlsbad.According to Carlsbad police, the 19-year-old motorcyclist was riding along the 4600 block of Carlsbad Boulevard when he collided with a Toyota Tundra around 4:35 p.m.Emergency responders arrived and transported the motorcyclist to the hospital but he was pronounced dead on the way.The driver of the Toyota, a 38-year-old man from Grand Terrace, stopped on the scene.Investigators have not said what caused the collision. They were still looking for witnesses to come forward. Anyone with information is urged to call Corporal Travis Anderson at 760-931-2208. 682

Can you trust the polls? It is a question on the minds of plenty of voters ahead of Election Day. 2016 CREDIBILITY ISSUE A major reason some voters are skeptical of the polls is because of 2016. The day before the election in 2016, Real Clear Politics Polling Average, had Hillary Clinton up +6.5% in Wisconsin. President Donald Trump went on to win Wisconsin by around 0.7%. A similar story unfolded in Michigan.EXPERTS WEIGH IN "Polling gives us a window into who we are as a people," Patrick Murray of the Monmouth Polling Institute said. “I think it really lets the public in on the secret of what the campaigns know," Lee Miringoff of the Marist College Poll said. Both pollsters are ranked as some of the most respected in the country. Both defend the polling process but acknowledge mistakes were made by some in 2016. "The problem that we had in 2016 was not that polling was any more inaccurate than it had been in the past. It was just that the inaccuracies happened to be in one particular direction," Murray said. What pollsters now know is then-candidate Donald Trump persuaded white voters to break with long-held, predictable voting habits and vote for him. Polling samples that once represented the population at-large, no longer did. "The media looked at that and portrayed what we were showing there as being more precise of a prediction than it could ever be," Murray said. These pollsters do not believe a "Silent Trump Voter" exists -- that is someone who is reluctant to tell a pollster they support Trump. “The so-called secret Trump voter doesn’t exist in terms of polling and the idea that polling is missing certain voters," Murray said. "Here you have a president now for 3 1/2 years, almost four years, as president of the United States, so people aren't going to feel a great reluctance to speak to their feelings on that topic," Lee Miringoff said. WHAT SHOULD YOU BELIEVE?Both pollsters agree that taking a range of polls and not any one in particular may be the best way to approach polling. “So the polls, you know, can be trusted not to sway you necessarily but to inform," Lee Miringoff said. "I think the idea behind averages is a good one. Because there always is going to be a range of result," Murray said. 2254

CARLSBAD, Calif. (KGTV) - A La Jolla man bought Carlsbad Fire Station 3 from the city and is making renovation plans so he can move in.Carlsbad firefighters worked out of the fire house on Catalina Drive for 40 years before moving to a newer, bigger station down the street in 2016."We kinda miss them because it was nice having them here, but I do think it's great that he's moving in," neighbor Diane Nogle said.Neighbors said the firefighters were a huge part of their cul-de-sac. Charles Colletti, the new owner, said they brought a cake to a neighboring girl's home on her birthday.Colletti said he bought the house for 3,000 to move closer to his daughter and grandchildren. Wednesday he walked through the home with a contractor, designing the future, "it needs a lot of work, the outside looks like a Brady Bunch house."Some of those proposed changes: new floors, new appliances, extending the kitchen, demolishing the fire chief's room downstairs, and moving the awkward bathroom in the middle of the floor plan.Colletti insisted he didn't want to take the fire station out of the house."I would love to keep some fire department, fire engine, stuff, memorabilia," Colletti said. "I was actually searching for a classic fire truck that I could potentially restore that I could keep here."Another selling point for him and a place that won't see much change is the garage.Colletti is planning on storing his classic car collection inside. Fourteen in all, including BMWs, Porsches, and Volkswagens.The only thing Colletti noticed that was missin: a fire pole. "We're considering installing one, just so when everybody asks me the question I can say yes, it does." Colletti said that's been one of his most asked questions. Colletti said he wants the station to continue serving the community, whether that's rescued pet adoptions with Second Chance, or bringing the firefighters back to the neighborhood."I'd love to reach out to them and invite them over to block parties because they're not that far away."Colletti will be moving in on July 15. He'll be staying in the garage while construction is underway.Colletti says he wouldn't have been able to buy the house without the help of his selling agent, Jenn Lynn, with Pacific Sotheby's. 2259

CAMPO, Calif. — Campo Elementary School students were forced off a school bus after a man stormed onto the bus armed with two knives.Matthew Barker, 37, of Campo, was arrested by the San Diego Sheriff's Department after he boarded the bus packed with students at an apartment complex on Friday around 8:30 a.m., according to Mountain Empire Unified School District superintendent Kathy Granger.Officials said Barker entered the bus and was immediately told by the driver to leave. Barker ignored the driver and continued up the stairs and toward students before the driver got in front of him.As Barker tried to push past the driver, a grandmother of one of the students saw what was happening and got onto the bus to help the driver, officials said. That's when Barker reportedly pulled out a knife and swung at the driver.As the driver and grandmother struggled with Barker, an older student ushered students to the back exit of the school bus and called to nearby parents for help. The students were able to exit out of the bus unharmed.Another good Samaritan then got on the bus, at which point Barker turned the knife on himself, according to the Sheriff's Department. The Samaritan pried the knife away from Barker and pulled him off the bus as deputies arrived.Barker has been charged with felony assault. Authorities are investigating the incident and believes drugs were a factor in the attack.The bus driver and Samaritans were not injured."We take safety very seriously and want to assure you our buses remain a safe form of transportation for getting children to and from school," Granger said in a statement. 1669

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