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SAN DIEGO (KGTV) - In celebration of National Pool Opening Day and in anticipation of the summer season, San Diego leaders will hold a community water safety festival Saturday.The 10th annual "April Pools Day" event will be held at Bud Kearns Pool, at 2229 Morely Field Dr., featuring swim assessments, CPR demonstrations, and safety presentations to educate about safe water practices.The event will also hold a cannonball kickoff and giant inflatable obstacle course for kids.RELATED: National Pool Opening Day signals summertime swimmingThe community water festival is aimed at waterproofing San Diego, through a multi-step approach to drowning prevention, swimming lessons, and beach safety training.As San Diego readies itself for the summer, the Prevent Drowning Foundation of San Diego will also hold a number of free swimming lessons and CPR demonstrations around the county. A full list can be found on the organization's website. 952

SAN DIEGO (KGTV) — Jayce Tingler doesn't plan to be a homebody in the San Diego Padres clubhouse."I want to be shagging in the outfield ... If you're out being active, more organic natural moments will arrive," Tingler told reporters, saying that he doesn't plan to sit in his office often.The Padres introduced the former Texas Rangers coach to the media at Petco Park Thursday. In front of a backdrop of brown and gold, general manager A.J. Preller spoke on Tingler's experience and confidence in him managing the team starting in 2020. Notably, Preller said he was looking for someone players would "run though a wall for" in his search.RELATED: San Diego Padres to unveil new 2020 uniforms in NovemberBefore Tingler arrived in San Diego to don number 32, he worked with the Rangers has a field coordinator and interim bench coach. Preller hailed Tingler's experience in player development for the organization, and bilingual and communication skills. The duo worked together while Preller was a scout and assistant general manager in Texas. Preller said Thursday that Tingler had showed him that he's "comfortable being uncomfortable" from his success as a young manager in the Dominican Republic.But the big question for many outside of Preller's is Tingler's experience. He becomes the Padres 21st manager in franchise history and the team's sixth-straight skipper without prior MLB managerial experience."Look, I'm going to make mistakes. My guess is at some point the players are going to make mistakes. So we have some common ground," Tingler said. "I hope to learn quick. I hope to have people around from various areas of expertise."Part of the expected change between 2019 to 2020 will include other coaching positions. Tingler says he's looking to surround himself with a staff that pushes players."We're in that process. We're meeting with people. The bottom line, can you build relationships and can you impact players, can you push them and make them better," Tingler said.Tingler walks into a club that has under delivered for the last decade. Last season marked the Padres' ninth-straight losing season. Former manager Andy Green didn't fair better, posting a .428 win percentage during his four seasons with the team.The last time the team finished above .500 was in 2010, under then-manager Bud Black.To that, Tingler says he's confident in the current squad of players and looks forward to his new staff forming those all important relationships to impact young players — hopefully producing a winning season."We've got a lot of players with huge upside ... I think they shared that kind of undying passion to win here in San Diego," Tingler said. 2676

SAN DIEGO (KGTV) - It's a great weekend to get out and enjoy San Diego's springtime with music, brews, and some heavy machinery.Del Mar's Goodguys 18th Meguiar's Del Mar Nationals roars into town, giving car heads the ultimate opportunity to see hot rods, muscle cars, and more.On the music scene, Snoop Dogg and Warren G will kick off the weekend with a show at The Observatory, and American Mariachi will debut at the Old Globe Theatre.RELATED: Springtime festivals in San DiegoFor locals looking for a festival, you can't go wrong with Julian's Gold Rush Days or the San Marcos Spring Festival and Street Fair.Here's a look at some of the things happening around San Diego this weekend:THURSDAY 710

SAN DIEGO (KGTV) -- Millennials are leaving San Diego in the thousands, according to a new report by Brookings. The new Census Bureau migration data reveal a post-recession shift in the migration of young adults and seniors. From 2007 to 2012, San Diego lost more than 7,400 people between the ages of 25 to 34 annually. From 2012 to 2017, the number dropped slightly to a little more than 7,000. RELATED: San Diego's median rent more than starting salaries for Class of 2019 483

SAN DIEGO (KGTV) — In some of the most severe cases of COVID-19, doctors are finding it’s not the coronavirus making people critically ill.It’s their own immune system, and a San Diego-based biotech company thinks it has an answer.La Jolla-based INmune Bio announced Tuesday it has FDA approval to begin a Phase 2 clinical trial on its inflammation fighting drug, Quellor.In many of the sickest COVID patients, doctors have noticed their blood is filled with high levels of immune proteins called cytokines. Cytokines act as messengers between cells and the virus can cause them to go haywire, setting off what’s known as a cytokine storm.In a cytokine storm, the body’s immune system starts to attack its own cells and tissues rather than the virus. During the Spanish Flu of 1918, many of the deaths were caused by cytokine storms.“You need to control the cytokine storm to keep patients from getting sick,” said INmune Bio’s CEO Dr. R.J. Tesi.There are several different types of cytokines. A drug undergoing testing in a federal trial with remdesivir targets a cytokine called beta interferon.The San Diego biotech’s drug Quellor suppresses a very specific cytokine called soluble tumor necrosis factor, which Dr. Tesi calls “the master cytokine” because of its role in triggering other immune proteins.Dr. Tesi said this particular cytokine may contribute to another troubling issue with COVID-19: blood clotting.“When they write the history of COVID-19, the clots are going to be the bad guy,” Dr. Tesi said. “These blood clots go off everywhere and they gum up the works. They make it so the lungs can't work. They make it so the kidneys can't work. They make it so the heart is screwed up. Make it so you have strokes.”INmune Bio, which is publicly traded but has just six full-time employees, is hoping its drug can address both the blood clots and the inflammation.The company plans to enroll 366 hospitalized COVID-19 patients for a Phase 2 trial to see if intervention with Quellor can keep people off ventilators and out of the ICU. 2053