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WASHINGTON, Aug. 4 (Xinhua) -- U.S. scientists have found two gene mutations occurring in oligodendrogliomas, the second-most common form of brain cancer, according to a study to be published Friday in journal Science.For years scientists have been looking for the primary cancer genes involved in oligodendrogliomas evolvement. Scientists know the two chromosomes held the probable mutations, but the particular gene information remains unclear.Now scientists at Duke University Medical Center and Johns Hopkins University have discovered the most likely genetic mutations that researchers have been hunting for on chromosomes 1 and 19.The genes they identified, CIC or FUBP1, are tumor suppressor genes. The cancer-related pathways that involve these genes could become targets for future treatments, said Hai Yan, a Duke associate professor of pathology and co-corresponding author of the study.The researchers found CIC on chromosome 19 and FUBP1 on chromosome 1 based on an initial study of seven oligodendrogliomas. They found six mutations and two mutations, respectively, in the seven tumors. Further study of 27 more of these tumors showed that there were 12 and three mutations of CIC and FUBP1, respectively. The two genes were rarely mutated in other types of cancers, indicating that they are oligodendroglioma-specific genes.These genes were difficult to find until the technology improved, said Yan."The team used whole genome sequencing technology so that no genes would be excluded, and we found to our surprise that one gene, on chromosome 19, was mutated in six out of the seven initial tumor specimens we sequenced," Yan said. "A mutation frequency of 85 percent is very high."The finding of two additional new genes involved in oligodendrogliomas increases the chances for an effective combination drug therapy for the tumor, Yan said. He envisions a combination cocktail of drugs similar to the combination-drug treatments taken by HIV patients that would target different pathways involved in cancer, and assist both in reducing the chance of relapsing and increasing odds of success.

BEIJING, Aug. 31 (Xinhuanet) – The pressure of modern society is taking a toll on sexual satisfaction, experts say following the release of an online survey.About 34 percent of people polled in the survey said that they are unsatisfied with their sex lives, with 6.5 percent "very unsatisfied".Another 32 percent condemned their sex lives as "just so-so".The survey interviewed more than 3,000 people, aged between 15 and 55, with men accounting for 74 percent of the interviewees.It was conducted by the China Population Communication Center and the Shanghai Academy of Social Sciences from May 1 to June 20. The survey did not give a margin of error.Only 23 percent of respondents said that they are "satisfied" with their sex lives, with 3.6 percent "very satisfied", according to the survey.But women seem to have a higher rate of satisfaction than men, with only 26 percent saying they are unsatisfied. The rate for men is 42 percent.The rate of sexual satisfaction among Chinese people is below the global average of 44 percent, according to an earlier survey by Durex. The 2007 Durex Global Sexual Wellbeing Survey questioned more than 26,000 people in 26 countries about all aspects of their sex lives - including satisfaction levels.Jiang Hui, president-elect of the Chinese Society of Andrology, attributed the lower rate of sexual satisfaction among Chinese people to rapid economic growth, which inevitably increases work and social pressure.Health problems associated with a modern lifestyle, such as diabetes and hypertension, are also to blame, he said.Jiang said his department of andrology used to receive about 10 patients a day 10 years ago. Now the figure has risen to more than 250.Rising awareness of sex and a more open attitude toward the once-taboo topic among the public also contributed to higher sexual expectations, he said.The survey also revealed that about 30 percent of respondents in the 35-55 age group had sex less than once a week."That rate is quite low, compared with the global average of 103 times a year, or 1.98 times a week," said Yang Xiong, who heads the social survey center at the Shanghai Academy of Social Sciences.Only 16.9 percent of respondents said that they had sex more than 10 times a month. Most respondents had sex three to nine times every month.About 8 percent of respondents said that they basically had no sex at all or it was too infrequent to be classified.The survey seemed to find that the more you made, the less you had. Those who earned at least 9,000 yuan (,400) a month had less sex than those who earned less, according to the survey.Among those making more than 9,000 yuan per month, over 70 percent said they had sex less than twice a month, compared with 16.5 percent for those with a monthly salary of less than 6,000 yuan.The survey also found that when people run into problems with their sex lives, 83 percent turn to the Internet, rather than professionals, for help. Less than 6 percent said they would see doctors to solve sex-related problems.Nearly 70 percent of those polled said they suffered from sexual health problems, such as erectile dysfunction (ED)."Many patients, especially men, are reluctant to see a doctor, which they think harms their manhood," Jiang said.According to a study conducted by the Chinese Society of Andrology, at least 40 percent of men aged 40 and above suffered from erectile dysfunction, roughly the global average.But Yang, from the Shanghai academy, noted that surveys conducted online tend to produce far different results than those conducted face-to-face.He expressed reservations about the survey's accuracy and said the public should only use the results for reference.

BEIJING, July 5 (Xinhuanet) -- A new study showed that environmental factors may play a larger role in the development of autism than previously recognized, according to media reports on Tuesday.The new study in the Archives of General Psychiatry looked at 192 pairs of twins in California. It found autism was surprisingly common in fraternal twins, despite the fact that they don’t share as many of the same genes as identical twins, suggesting that something in their mutual life circumstances may be playing at least as strong a role as genetics.The study, which will likely be followed up with similar studies of twins and other siblings, could  force a dramatic swing in the focus of research into the developmental disorder.“It looks like some shared environmental factors play a role in autism, and the study really points toward factors that are early in life that affect the development of the child,” said study researcher Joachim Hallmayer, MD, an associate professor of psychiatry at Stanford University in California.

COPENHAGEN, May 30 (Xinhua) -- The number of confirmed E. coli cases has risen to 14 in Denmark, with at least 26 others suspected of having the intestinal infection, the National Serum Institute said Monday.Seven of the confirmed cases show symptoms of kidney failure which marks an advanced stage of the sickness, the institute said."Almost all of the 14 infected people have been in northern Germany recently except just one. There is a 24-year-old man from Jutland. He has not even been to Germany, so he does not quite fit with the rest of the pattern," said Kaare Moelbak, chief physician at the institute. "We do not know yet how he has been so unlucky to get this infection but we assume that it has been a person-to-person transmission, or that he has eaten infected vegetables," he added.Denmark's Veterinary and Food Administration (DVFA) had advised Danish consumers not to eat raw tomato, lettuce and cucumber from Germany, and cucumber from Spain.It is now checking Danish cucumbers for traces of E. coli, with results expected on Tuesday.

BEIJING, Sept. 14 (Xinhuanet) -- The U.S. Food and Drug Administration (FDA) on Monday announced a recall on a drug infusion pump of Medtronic, the Associated Press reported.The recalled drug pump was called "SynchroMed II", including models of 8637-20 and 8637-40, distributed between 2004 and July 2011.Drug infusion pump was used to deliver the drugs for patients to treat chronic pain, spasms as well as other conditions.The pumps' malfunction could put patients in the risk of either recurrent or withdrawal symptoms, which could be life-threatening, FDA warned.There were 55 reported cases and one death related to the drug withdrawal, among a total 139,653 SynchroMed II pump implants worldwide, FDA notified.The problem was due to a film within the pump's battery that could stop the therapy, FDA said.Medtronic, the U.S. medical technology company based in Minneapolis, is not recommending patients to remove the pumps, but instead, encourage patients to contact their doctor if they hear the device alarm.