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People are using a chemical used to calibrate machines to get high that is so powerful it's nearly Narcan resistant.Some dealers are passing off this new drug as fentanyl. But the reality is much worse. It's a hazardous chemical mixed with fentanyl called tetrahydrofuran fentanyl."It's got other opioid effects. Some of these things are 100 or 1,000 times more potent than heroin," said Dr. Michael Miller of Rogers Memorial Hospital in Oconomowoc.The drug is new to Wisconsin, but law enforcement has found it in Florida and Georgia. Last week, a Pennsylvania man, Jeremy Achey, 43, was sentenced to life in prison for supplying tetrahydrofuran fentanyl.According to federal court records, a man overdosed and his fiancee died when they bought it from him over the internet. Prosecutors say the seller told customers, "It is best if you snort it, shoot it, or smoke it."Miller said most addicts do not even know they are taking this synthetic fentanyl."Most people who are exposed to synthetic fentanyls are not using them intentionally. They are not desiring to use them because they understand that the potency is so high it could be lethal," Miller said.Achey is believed to have mailed thousands of packages containing the drug to customers throughout the United States. In order to survive it, Miller warned you would need a large dose of Narcan."It's the fentanyl part that is really fatal because it shuts down your breathing and you die instantly," said Miller. "You use as much opioid reversal agent as you possibly can, you support them, you put them on a ventilator." The Milwaukee County Medical Examiner's office could not say where the person who died in Milwaukee got the tetrahydrofuran fentanyl. But they warn if one person has it likely others do as well. 1808

PASADENA (CNS) - Joe Coulombe, the San Diego native who founded the Trader Joe's grocery chain and grew it from a single outlet in Pasadena to more than 500 stores in 40 states, has died following years of declining health. He was 89.Coulombe's son, Joe Jr., told reporters his father died late Friday at his home in Pasadena where he had been under hospice care."We're going to miss him a lot," his son told the Pasadena Star- News. "I think people are going to remember the wonderful Trader Joe's concept he put in place, and especially his treatment of his employees. He really cared about them."Those memories were already trending on social media early Saturday, with special note being made of Trader Joe's wages and unique, healthy foods."Trader Joe's is a model that every business should emulate," Twitter user NYGiantsfan74 posted. "The products are great, the prices are great and every ... employee is happy. I love Trader Joe's. Please don't ever change and become greedy."Another user simply expressed thanks "for Pirate's Booty and your free sample station."Coulombe, a San Diego native who was raised in Del Mar and earned a master's in business administration from Stanford University, began his retail career in 1958. His bosses at Rexall Drugs hired him to open a chain of 7-Eleven style convenience stores, which he later bought when the company abandoned the idea.But as 7-Eleven began encroaching on his territory, Coulombe shifted to what would become the Trader Joe's model: healthy foods that shoppers could not find in other markets, sold at reasonable prices in stores with South Seas nautical decor and employees dressed in Hawaiian-style shirts.The first Trader Joe's opened in 1967 on Arroyo Boulevard in Pasadena where it still stands Saturday, having spawned scores of similar outlets nationwide.Along the way, Trader Joe's gained a loyal following for everything from its "Two Buck Chuck" Charles Shaw wine and skincare products to its periodic "Fearless Flyer" newsletter, featuring the latest products and occasional behind-the-scenes podcast."Scientific American had a story that of all people qualified to go to college, 60 percent were going," Coulombe told the Los Angeles Times for a 2014 profile. "I felt this newly educated -- not smarter but better educated -- class of people would want something different, and that was the genesis of Trader Joe's."In later years, Coulombe became a noted philanthropist providing support for such organizations at the Los Angeles Opera and the Huntington Library, Art Collections and Botanical Gardens, sat on several corporate boards and thrived as an amateur painter and occasional food and wine commentator.Coulombe, who retired in 1988, is survived by his wife of 67 years, Alice, three children, and six grandchildren."He was a brilliant thinker with a mesmerizing personality that simply galvanized all with whom he worked," Trader Joe's CEO Dan Bane said Saturday. "He was not only our founder, he was our first spokesperson. He starred in captivating radio ads for years, always signing off with his unique, 'thanks for listening.' Joe developed a cadre of leaders that carried on his vision and helped shape Trader Joe's in the early years." 3237

Paul Manafort and Rick Gates' case has added a new criminal charge or charges as of Wednesday, though whether the action is additional grand-jury approved indictments or indicates a coming a plea agreement remains a mystery.A record-keeping book in the federal courthouse in Washington included a new sealed filing in Manafort and Gates' case, which was opened in late October when the former Trump campaign advisers pleaded not guilty to money laundering and failure to properly disclose their foreign lobbying work. The filing contained no additional information.The filing could indicate additional indictments in the case, or it could be a type of charge called a criminal information, which would indicate an agreement between prosecutors and a defendant.Prosecutors on Manafort's case said on Friday they found evidence of bank fraud and related conspiracies, for which Manafort had not been charged.CNN has also reported that Gates has spoken to prosecutors about his case and has been negotiating a plea deal for more than a month. It's still unclear this week whether he is closer to finalizing an agreement. Both Manafort and Gates maintain their not guilty pleas.A European lawyer who worked with Gates and Manafort years ago pleaded guilty Tuesday to lying to special counsel Robert Mueller's investigators about his interactions with Gates and an unnamed Ukrainian. Gates at courthouse 1411

Photos show what appears to be a person dressed like Hitler at a Halloween event near Las Vegas.The pictures were snapped during a trunk-or-treat Halloween event at Veterans Memorial Park in Boulder City, Nevada on Friday.Folks noticed someone dressed up as Hitler, down to swastikas on the side of his sleeve.The posts quickly spread over the weekend across many Boulder City and Las Vegas Facebook pages.The 12-year-old boy’s father said his son was studying World War II and the evil dictator at school.He says his son just wanted to wear the costume. The father added his son is just a child and didn’t mean to offend anyone, and says this whole thing is blown out of proportion.KTNV in Las Vegas spoke with the area chapter of the Anti-Defamation League, who says the costume promotes hate and indifference.“Even though nothing illegal happened, it was very offensive and can't be allowed to be the norm,” said Jolie Brislin, Anti-Defamation League. 962

PHOENIX — Three people, including two children, have died after being stabbed near 19th and Glendale avenues Sunday morning.Phoenix police say they are conducting a homicide investigation after they found a 7-year old boy, 9-year-old girl and an 18-year-old woman who had been stabbed to death inside of an apartment. Authorities say a 28-year-old man was also stabbed and transported to the hospital in extremely critical condition.Officials say they received a call of unknown trouble, possibly a stabbing at about 9 a.m.A person came into the apartment soon after the stabbing and found the four victims and called officers to the scene.The two children are believed to be siblings and the 18-year-old woman and 28-year-old man are believed to be family members.Police say there are currently no outstanding suspects and the investigation is ongoing.Anyone with information is encouraged to call police at 602-262-6141 or to remain anonymous, call Silent Witness at 480-WITNESS/480-TESTIGO (Spanish). 1011

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