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WASHINGTON, July 20 (Xinhua) -- The loss of a protein that coats sperm may explain a significant proportion of infertility in men worldwide, according to a study by an international team of researchers led by University of California Davis.A paper describing the work was published Wednesday in the journal Science Translational Medicine. The research could open up new ways to screen and treat couples for infertility.The gene DEFB126 encodes a protein called Beta Defensin 126, which coats the surface of sperm and helps it penetrate cervical mucus in the female. A survey of samples from the U.S., Britain and China showed that as many as a quarter of men worldwide carry two copies of the defective gene.In the new study, researchers found that men with a muted DEFB126 lack Beta Defensin 126, making it much more difficult for sperm to swim through the mucus and eventually join with an egg.Examining 500 newly married Chinese couples, researchers found that the lack of Beta Defensin 126 in men with the DEFB126 mutation lowered fertility (even among men that did not display other deficiencies usually associated with infertility, like inadequate semen volume and low sperm motility). Wives of men with the Beta Defensin 126 variant were significantly less likely to become pregnant than were other couples, and 30 percent less likely to have a birth.This genetic variation in DEFB126 likely accounts for many unexplained cases of infertility, researchers say. They hope next to work with a major infertility program in the U.S. to further explore the role of the mutation.
BEIJING, Sept. 20 (Xinhua) -- Floods and landslides triggered by recent heavy rains in eight of China's provincial-level regions have left 70 people dead and 32 others missing this month.Heavy downpours, floods and other related disasters have affected Sichuan, Shaanxi, Henan, Chongqing, Hubei, Shandong, Shanxi and Gansu, the National Disaster Reduction Commission said in a statement released on Tuesday.As of Tuesday, these disasters have affected 21.56 million people and caused an estimated 26.09 billion yuan (4.08 billion U.S. dollars) in direct economic losses, the statement said.

SAN FRANCISCO, Sept. 22 (Xinhua) -- Former eBay Chief Executive Officer and California governor candidate Meg Whitman on Thursday was named Hewlett-Packard's new CEO, replacing Leo Apotheker who served 11 months on the job."We are fortunate to have someone of Meg Whitman's caliber and experience step up to lead HP," said the California-based company in a statement."We are at a critical moment and we need renewed leadership to successfully implement our strategy and take advantage of the market opportunities ahead," said the troubled tech giant.It noted that the job of the HP CEO now requires additional attributes to successfully execute on the company's strategy, adding Whitman "has the right operational and communication skills and leadership abilities to deliver improved execution and financial performance.""I am honored and excited to lead HP. I believe HP matters -- it matters to Silicon Valley, California, the country and the world," said Whitman in a statement.Whitman, 55, joined the HP board in January and served as president and CEO of eBay from 1998 to 2008, when she led the company through its initial public offering and massive growth.During her last years at eBay, she is blamed for not being able to halt the sales slowdown and overpaying for the 2005 acquisition of Skype with 4.1 billion dollars. In 2009, Skype was sold by eBay at a valuation of 2.75 billion dollars.Whitman won the Republican nomination for governor of California in 2010. She lost the election to Gov. Jerry Brown after spending more than 140 million dollars of her own fortune on the campaign. EnditemHP said the appointments are effective immediately, following the decision that Apotheker stepped down as president and CEO and resigned as a director of the company.Multiple U.S. media reported on Wednesday that Apotheker was to be ousted, sending HP shares soaring on the market and in the after-hour trading.Apotheker, 58, was named HP CEO 11 months ago to replace Mark Hurd, who was ousted due to a scandal over a personal relationship with a company contractor and then became co-president of Oracle. Before HP, Apotheker had served as CEO of German software giant SAP for 10 months.On Aug. 18, Apotheker announced that HP will shut down its mobile business, spin off its core personal computer business and transfer into a cloud-based software and services provider for businesses including a 10.3 billion-dollar acquisition of British software company Autonomy.Shares of the company plunged 20 percent the following day, the worst one-day loss since Black Monday in 1987.On Sept. 30, 2010, the day before Apotheker's appointment as HP CEO, the tech giant's stock closed at 42.04 dollars. On Tuesday, the price closed at 22.47 dollars, a decrease of 46.6 percent in less than a year.On Monday, HP was reported to begin sending over 500 employees pink slips in the WebOS division, after announcing to stop making WebOS devices in August.
THE HAGUE, June 1(Xinhua) -- Five people in the Netherlands have been sickened with an unusual strain of the E. coli bacteria, the institute for public health (RIVM) reported Wednesday.Of the five patients, four also suffered from intestinal problems and renal failure. The five who are infected all had recently been in Germany.The patients were infected with enterohaemorrhagic E.coli, or EHEC, a particularly deadly strain of the common bacteria found in the digestive systems of cows, humans and other mammals.The outbreak has hit at least eight European countries but virtually all of the sick people either live in Germany or recently traveled there.Medical authorities appeared no closer to discovering either the source of the infection or the mystery at the heart of the outbreak: why the unusual strain of the E. coli bacteria appears to be causing so many cases of hemolytic uremic syndrome, which attacks the kidneys and can cause seizures, strokes and comas.Earlier this week German researchers showed that Dutch cucumbers were not the cause of the contamination."It is essential to quickly find the source, as long as that is not found, the contamination can spread. It's a very aggressive bacteria and many people are seriously ill," a RIVM spokesman said.
WASHINGTON, June 21 (Xinhua) -- Brain cancer patients who are able to exercise live significantly longer than sedentary patients, U.S. scientists at the Duke Cancer Institute have reported.The finding, published online this week in the Journal of Clinical Oncology, adds to recent research that exercise improves how cancer patients feel during and after treatments, and may also extend their lives.The study enrolled 243 patients with advanced recurrent gliomas, lethal brain malignancies that typically result in a median life expectancy of less than six months. The patients who reported participating in regular, brisk exercise -- the equivalent of an energetic walk five days a week for 30 minutes -- had significantly prolonged survival, living a median 21.84 months versus 13.03 months for the most sedentary patients."This provides some initial evidence that we need to look at the effects of exercise interventions, not only to ease symptoms but also to impact progression and survival," said Lee Jones, associate professor in the Duke Cancer Institute and senior author of the study.
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