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WASHINGTON, Dec. 7 (Xinhua) -- Drugs that affect the levels of an important brain protein involved in learning and memory reverse cellular changes in the brain seen during aging, according to an animal study published Wednesday in the Journal of Neuroscience. The findings could one day aid in the development of new drugs that enhance cognitive function in older adults.Aging-related memory loss is associated with the gradual deterioration of the structure and function of synapses (the connections between brain cells) in brain regions critical to learning and memory, such as the hippocampus.Recent studies suggested that histone acetylation, a chemical process that controls whether genes are turned on, affects this process. Specifically, it affects brain cells' ability to alter the strength and structure of their connections for information storage, a process known as synaptic plasticity, which is a cellular signature of memory.In the current study, Cui-Wei Xie, of the University of California, Los Angeles, and colleagues found that compared with younger rats, hippocampi from older rats have less brain-derived neurotrophic factor (BDNF) -- a protein that promotes synaptic plasticity -- and less histone acetylation of the Bdnf gene. By treating the hippocampal tissue from older animals with a drug that increased histone acetylation, they were able to restore BDNF production and synaptic plasticity to levels found in younger animals."These findings shed light on why synapses become less efficient and more vulnerable to impairment during aging," said Xie, who led the study. "Such knowledge could help develop new drugs for cognitive aging and aging-related neurodegenerative diseases, such as Alzheimer's disease," she added.

BEIJING, Jan. 10 (Xinhua) -- China's energy chief said here Tuesday that the country is under greater pressure to ensure energy supply this year as both demand and international competition for resources grows.Liu Tienan, head of the National Energy Administration (NEA), made the remarks when speaking at a national energy work conference."It is always worrisome to have to sustain supply of energy and resources for a country with 1.3 billion people," Liu said.As China is facing a "grim situation" in energy saving and emission reduction, Liu noted, it is urgent to restructure the country's energy use and control the gross consumption volume this year.To ensure a stable energy supply, China will optimize the layout of energy exploration, start construction of energy-transmission projects and other major energy programs while boosting reserves of oil, natural gas and coal in 2012, Liu said.The NEA plans to add another 200 metric tons to the country's coal-producing capacity this year plus 70 million kw of new installed power-generating capacity.If the ecology is protected and people are relocated, China will start construction of hydropower projects of 20 million kw in 2012, according to the NEA.Once safety is ensured, nuclear power will be developed after the country's new safety plan is approved.As for renewable energy development, the NEA plans to launch wind power projects with a total capacity between 15 million kw and 18 million kw, while developing 3 million kw of solar power over the new five-year period ending 2015.Liu said, in 2012, the country aims to provide electricity to another 600,000 people who currently have no access to it and expand electricity access to 5 million people by 2015.The NEA has budgeted 65 billion yuan (10.3 billion U.S. dollars) for upgrading the grids in rural areas.Over the next four years, China will facilitate the development of non-conventional natural gas, such as shale gas and coalbed methane by increasing the number of natural gas users by 100 million to 250 million.A key indicator measuring the economic vitality, power consumption rose 11.7 percent year-on-year to 4.7 trillion kWh in China in 2011. The growth in 2012 is expected to slow to 8.5 percent amid the country's economic slowdown.

YANGON, Nov. 10 (Xinhua) -- Myanmar surgeons have successfully separated the fifth conjoined twin baby girls, official media reported Thursday.The surgical operation by Dr. Htoo Han and his assistants was performed on the two-year-and-one-month-old conjoined twins named Ma Ingyin Khaing and Ma Ingyin Hlaing in the Children's Hospital in Yangon Wednesday, according to the New Light of Myanmar daily.The separated twins, who are under extensive care in the hospital, are from Kawtin village in Laungton township in southern Tanintharyi region.Myanmar surgeons had carried out four successful similar surgical operations on twins in the past over two decades.The fourth twins, who are also baby girls named So Pyay Lin and So Pyay Win with their chests joined together, were successfully separated in October 2009.

OTTAWA, Nov. 21 (Xinhua) -- The leader of World Health Organization (WHO) Margaret Chan said in Canada on Monday that countries must make the health of women and children their highest priority.Speaking at a luncheon in Gatineau, Quebec, Chan said that maternal and infant health is the most pressing public health issue in the world.She made the remarks just hours after WHO announced Chan was the only candidate for the position on WHO director-general when Chan's appointment expires next year.An executive board meeting in Geneva between Jan. 16 and 23 will decide whether to put the name forward to the WHO Assembly in May, which would make the final decision regarding the appointment.Chan, a former health chief in China's Hong Kong, was elected director-general of the WHO in Nov. 2006.Before her tenure with WHO, Chan was head of public health in Hong Kong, where she managed the city's response to the world's first outbreak of the deadly H5N1 bird flu virus and an outbreak of Severe Acute Respiratory Syndrome (SARS).Speaking in Gatineau, Chan, who earned her medical degree in Canada, said that she never expected to rise to such a lofty position."I just wanted to be a doctor. I just wanted to take care of women and children. When I was studying in Canada, I thought I would get married and have children. I never guessed I'd do anything like head the World Health Organization," she said.She said that she will continue to focus the WHO's attention on mothers and young children.Chan said that it's difficult to know how many mothers and young children die of preventable diseases, since more than 80 countries don't keep accurate death records, but she said that millions of children under five years of age are dying.Millions more are growing up physically and mentally stunted because of poor nutrition and medical care, she added."Without proper nutrition, the stunting we are seeing is horrific," she said. Unless babies have good food, including being breast-fed as infants, they grow up physically and mentally under-developed, Chan said."The first few years of a child's life are make or break," she said.Chan and the WHO held a meeting of the Expert Panel on Maternal and Child Health in Canada from Nov. 18 to Nov. 21. The panel was established by the United Nations Commission on Information and Accountability for Women's and Children's Health Report. At the invitation of the WHO, the Commission was co-chaired by Canada's Prime Minister Stephen Harper and the President of Tanzania, Dr. Jakaya Kikwete.Chan says she's hopeful funding from developed nations will continue to expand, despite the debt crisis facing many of them. The situation resembles the 1970s, with spikes in energy and food prices along with cuts to national budgets to restrain debt.Chan said she is relieved the International Monetary Fund will not press for public health cuts in countries that are struggling with debt.Beverley J. Oda, Minister of International Cooperation who is responsible for Canada's official aid affairs, delivered remarks at the luncheon on improving the health of children and mothers locally and globally."I am particularly proud of the strong partnership between the WHO and Canada in advancing global health, and working towards improvements that will help us achieve our shared goals," she said.Last Friday, Oda announced 25 new initiatives to further Canada 's support to 23 projects in Africa concerning Children and Youth, Food Security and Sustainable Economic Growth.Seven of these are multi-country projects supporting efforts to prevent the mother-to-child transmission of HIV/AIDS, further improving child health, or increasing the capacity of African Regional Technical Centres. The others are targeted to support work in a range of individual African countries by working with Canadian, international and African-based organizations.

ATHENS, Nov. 11 (Xinhua) -- The third Forum on the Development of Tibet concluded here on Friday after discussions on efforts to promote the world's understanding of Tibet and enhance the cooperation between China and the rest of the world with regards to Tibet's development.This year marks the 60th anniversary of Tibet's peaceful liberation. During the two-day event, delegates from Greece, Britain, France, Germany, India and Nepal expressed their opinions on Tibet's modernization and put forward valuable advice and suggestions based on their own experience and research findings.Some of the foreign delegates have visited Tibet many times before. Narasimhan Ram, Editor-in-chief of The Hindu from India and Brendan O'Neill, editor of the British magazine Spiked spoke positively about the preferential polices and financial support of the Chinese central government and other parts of China for the region.During the Forum, Wang Chen, head of the Chinese State Council Information Office met with the Greek political leaders and journalists from mainstream media.People got an opportunity to learn more about China as Nyima Tsering, Vice Chairman of the Standing Committee of the People's Congress of the Tibet Autonomous Region, introduced the development of Tibet and the Chinese government's policy towards the region.A number of Greek mainstream media covered the Forum.Over the past 60 years, Tibet has achieved a huge development in both its social structure and socio-economic development, said a communique released upon the end of the forum.It also foresees a great potential of cooperation with the international community in energy, environment, education and healthcare development for the region.The forum has facilitated better understanding of Tibet in the international community and will help to promote faster and better development of the autonomous region, the Communique said.

来源：资阳报