济南这个是包茎吗(济南性生活时间短要怎么解决) (今日更新中)

SAN DIEGO (KGTV) -- As Santa Ana winds move out of the region, a freeze warning was issued for portions of San Diego County.The National Weather Service issued a freeze warning for the county's valleys and deserts from midnight through 10 a.m. Friday. Overnight temperatures dropped into the low 30s, with a few areas seeing temperatures in the mid- to upper 20s.The warning will affect cities including Escondido, El Cajon, San Marcos, La Mesa, Santee, and Poway.RELATED: Winter returns to Southern California mountains 528

SAN DIEGO (KGTV) — California officials said Friday that a technical glitch caused data on hundreds of thousands of COVID-19 tests to go unreported.Despite the inaccurate data, officials say they are still seeing a trend showing a decrease in case rates. Hospitalization and death data, however, is collected differently and unaffected by the glitch.According to the state, the data system they use failed and that led to inaccurate case numbers and case positivity rates. That failure prevented counties from having some of the data they need to monitor and respond to the virus in local communities, like contact tracing.The state says that about two weeks ago, a server outage created a delay in lab records coming into the reporting system. At the same time, they realized they weren't getting data from one of the largest commercial reporting labs for about five days.California Department of Health and Human Services Secretary Dr. Mark Ghaly says the issues have been fixed."We expect that over the next 24 to 48 hours that the backlog that's between 250,000 to 300,000 cases will be resolved, giving us a better sense of the number of tests that were delayed," Ghaly told reporters on Friday. "We are reporting this data to the counties based on the date the specimen was collected so we can attribute it to the appropriate date."The state says the system was not built for the volume of data it's receiving. It's putting new systems in place and has created a backup system to double-check the data and reports.California's County Monitoring Watch List was paused last week so that the glitch does not play a role in decision making about county statuses.Gov. Gavin Newsom has ordered an investigation into what happened with the reporting system. 1764

SAN DIEGO (KGTV) — As the world waits for a vaccine against the coronavirus, two San Diego biotechs are teaming up to develop a nasal spray using designer antibodies cloned from COVID-19 survivors.About 70 companies worldwide are working on therapies for COVID-19 using cloned antibodies, according to an estimate by the International AIDS Vaccine Initiative. A few of these treatments, known officially as monoclonal antibody therapies, have advanced to clinical trials.Most require an injection, but San Diego-based Diomics and its partner Active Motif, based in Carlsbad, are developing a once-a-day spray that could be easily self-administered.Early research suggests the coronavirus primarily enters the body through the nose. The spray, called Dioguard, is designed to coat the lining of the nasal cavity with cloned antibodies that are held in place for 24 hours or more using a proprietary polymer material developed by Diomics.Diomics CEO Anthony Zolezzi said he believes the spray “holds the key to allowing many aspects of life to resume until the day comes when there’s an effective vaccine in widespread use.”Diomics is also developing two tests for COVID-19 antibodies using its polymer beads, including a device that looks like a nicotine patch that is designed to monitor for infections for a week or more.RELATED: How a dot on your forearm could be the future sign of COVID immunityActive Motif is providing the cloned antibodies for the nasal spray. With a lab in Shanghai and other relationships in China, the Carlsbad company was able to clone antibodies from 11 Chinese survivors in February, before the World Health Organization declared a pandemic.When the company started the cloning project, they thought the virus would probably disappear in three to six months, said Active Motif CEO Ted DeFrank. “Then people started realizing, no this is going to be with us for a while.”The plasma from the 11 Chinese patients contained thousands of antibodies, and scientists with Active Motif set about selecting the one that was most effective, dubbed 414-1. The company says it can neutralize SARS-CoV-2 virus particles with 98 percent effectiveness.Monoclonal antibodies have some similarities to convalescent plasma, which is a complex cocktail of antibodies and other immune molecules drawn from the blood of recovered patients. One of the key differences is that cloned antibodies can be mass produced in a lab.Cloned antibodies have been used in treatments for more than 30 years, primarily for cancer. One such treatment famously helped former U.S. President Jimmy Carter beat melanoma.But of the more than 100 monoclonal antibody therapies licensed for use, only seven are for communicable diseases, according to IAVI.Historically, the treatments have been expensive and difficult to produce, but Diomics said it’s targeting a price of about a spray for Dioguard, roughly per bottle.“We do not want to have huge profits from a pandemic, that’s just wrong,” Zolezzi said. “We’re going to price this as effectively as we can for the masses. We want to get this out to the masses.”Animal testing is about to begin and the companies said they hope to progress to human trials soon. Their goal is to release the spray in early 2021, when a vaccine may be on the market but not yet widely available.If the spray works, it could be adapted to other viruses to help fight future pandemics, Zolezzi said."That’s our real goal," Zolezzi said. "That we never get caught flat-footed like this time." 3526

SAN DIEGO (KGTV) — Currently, there are five vaccines that kids in California must get to attend school, and a lot of parents are wondering if the eventual COVID-19 vaccine will be added to that list.A website run by the California Department of Public Health seems to suggest that a change to the state’s immunization requirements may be imminent. In a message titled “COVID-19 Update,” state officials say immunization requirements “remain in place for now. Any updates will be posted here.”But history and medical science suggest it will take time before states make a COVID vaccine mandatory for children, according to Dr. Rahul Gupta, the chief medical and health officer at March of Dimes.SEE ALSO: States have authority to fine or jail people who refuse coronavirus vaccine, attorney saysMarch of Dimes is the non-profit organization that funded the search for a polio vaccine in the 1950s.“We’re seeing a repeat of history in so many ways,” Dr. Gupta said.Fear of the deadly polio virus prompted quarantines, social distancing and a run on breathing machines. In those days, doctors used iron lungs.With funding from March of Dimes, Dr. Jonas Salk launched a massive clinical trial on 1.8 million kids using his experimental vaccine in 1954. Almost exactly a year later, in April 1955, he announced the vaccine was safe and effective.Within days, five million kids got the first dose of Salk’s vaccine. But the State of California did not mandate the polio vaccine for children entering schools for six more years -- in 1961.The most recent vaccine added to California’s required immunization list was for chickenpox in 2000. That was five years after that vaccine became available in the U.S.When a COVID-19 vaccine is ready in the U.S., children will not be among the first inoculated, Dr. Gupta said. Unlike polio, the novel coronavirus tends to spare children from the most severe symptoms.“The supply will require us to make sure that we prioritize the highest risk population, including healthcare workers,” he said.It’s also unclear how children would respond to the COVID-19 vaccine. Current vaccine candidates against the coronavirus are being tested on adults not children, according to CDPH, and children mount different immune responses than adults.Experimental vaccines can also have difficulties in the production process. In the infamous Cutter Incident, one of the six labs licensed to produce the polio vaccine accidentally let live virus slip into the shots, leading to more than 250 cases of polio, including instances of paralysis and deaths.The incident prompted sweeping safety changes in the U.S.Dr. Gupta said the Cutter Incident shows vaccines need to be rolled out carefully.“We have to understand that that’s a process and we learn as we go along,” he said. “There could be some adverse events that happen from any drug, much less a vaccine that you take. Foods give you allergies. It’s not an unknown side effect.”State officials could a new vaccine to California’s mandatory list by passing a bill or through a regulation issued by CDPH.The process can often take years, but CDPH said in an emergency the process could be “greatly accelerated.” 3189

SAN DIEGO (KGTV) — Congressional candidate for the 53rd District and San Diego City Council President Georgette Gómez says she was unaware of an error on her 2017 tax return and says it was committed by her accountant.Gómez's 2017 tax return shows she reported almost ,000 from pension income but reported zero in actual wages. According to Transparent California, Gómez made more than ,000 that year from her job as a San Diego City Council member and an additional ,000.University of San Diego professor of law Ariel Jurow Kleiman specializes in federal tax law. ABC 10News reporter Adam Racusin asked her to look at the filing."There was a zero on the line where you would normally report your wages," Kleiman said.Discrepancies in Gómez's tax returns were first reported by the San Diego Union-Tribune.The numbers on Gómez's 2018 return also don't match the dollar amounts reported on a financial disclosure report for Congressional candidates.In a statement, Gómez says her accountant made the errors, but that she has filed a corrected return and paid back the taxes."You may have seen a story about my accountant’s errors on my taxes. Like most people, I trusted my accountant to file my taxes accurately and I was shocked to find out that my 2017 returns were not properly filed. My accountant has taken responsibility for the errors. But I, too, take responsibility and I’ve filed a corrected return and paid the back taxes," Gómez said in a statement.Currently, Gómez is facing off with fellow Democrat Sara Jacobs for California's 53rd District in Congress this November.The Gómez campaign team has been sending out emails pushing for Jacobs to release her returns.A spokesperson for Jacobs told ABC 10News, "The Gómez campaign spent weeks misleading voters and crying wolf about Sara's tax returns, only to have the real story be their candidate's own negligence. With 25 days until election day, now would be a good time for the Gómez campaign to get their own house in order."ABC 10News looked through Jacobs' tax returns as well. It shows most of her income came from dividends and capital gains. About million in 2019, million in 2018, and around million in 2017.Jacobs' tax returns show she paid around million in taxes over those years. 2283

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