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SYDNEY, Sept. 5 (Xinhua) -- Australian scientists believe " brown fat," a wondrous tissue that burns energy to generate heat, could help people fight obesity, local media reported on Monday.A research team from Sydney's Garvan Institute of Medical Research (GIMR) has worked out how to grow brown fat from stem cells biopsied from adults, raising hopes that one day brown fat could be transplanted in obese people to speed up calories they burn, the Australian Associated Press (AAP) reported.Garvan endocrinologist Paul Lee, who led the research, is optimistic about targeting brown fat as an obesity intervention, commenting "it's a highly metabolically active form of fat, and very exciting that we may be able to stimulate its growth in people."People are born with supplies of brown fat around their neckline to keep them warm as infants, according to scientists at GIMR.Scientists now know that brown fat is present in most, if not all, adults mainly just behind the collarbone.Studies have found that adults with brown fat are slimmer than those without."Although this is early work, it is a proof of concept study showing that the growth of brown fat cells is possible, using precursor cells taken from adult humans, under appropriate stimulation," Lee said."Regardless of whether or not someone has lots of or little brown fat, the precursor cells are universally present. Under the appropriate growth factor and hormonal stimulation, the cells all grow and differentiate into mature brown fat cells."However, Lee warned more work was needed.Lee said even if brown fat was transplanted into obese people or drugs developed to stimulate the growth of brown fat, exercise and a healthy diet would still be crucial to aiding weight loss."So I don't think this is a solution to obesity because there are so many other factors (involved in obesity)," he said."Despite how efficient brown fat is at burning energy, we would only need a few doughnuts to diminish or negate its benefits."Lee said it would be years before tests could be carried out on brown fat transplants.In the meantime, he is expanding his study to test different ways to grow brown fat.His study, to be printed in the October issue of Endocrinology, has been published in the online edition of the journal.

WASHINGTON, June 7 (Xinhua) -- Advanced hepatitis C patients with chronic liver disease may benefit from drinking coffee during treatment, according to a new study published Tuesday in Gastroenterology, the official journal of the American Gastroenterological Association Institute.The study shows that patients who received peginterferon plus ribavirin treatment and who drank three or more cups of coffee per day were two times more likely to respond to treatment than non- drinkers.Among non-drinkers, 46 percent had an early virologic response; 26 percent had no detectable serum hepatitis C virus (HCV) ribonucleic acid at week 20; 22 percent had no detectable serum at week 48; and 11 percent had a sustained virologic response. In contrast, the corresponding proportions for those who drank three or more cups of coffee per day were 73 percent, 52 percent, 49 percent and 26 percent, respectively."Coffee intake has been associated with a lower level of liver enzymes, reduced progression of chronic liver disease and reduced incidence of liver cancer," said Neal Freedman, of the National Cancer Institute and lead author of this study. "Although we observed an independent association between coffee intake and virologic response to treatment, this association needs replication in other studies."Approximately 70 to 80 percent of individuals exposed to HCV become chronically infected. Worldwide, these individuals are estimated to number between 130 and 170 million. Higher coffee consumption has been associated with slower progression of pre- existing liver disease and lower risk of liver cancer. However, the relationship with response to anti-HCV treatment had not been previously evaluated.

LOS ANGELES, June 17 (Xinhua) -- The size of low-oxygen zones created by respiring bacteria is extremely sensitive to changes in depth caused by oscillations in climate, thus posing a distant threat to marine life, a new study suggests."The growth of low-oxygen regions is cause for concern because of the detrimental effects on marine populations -- entire ecosystems can die off when marine life cannot escape the low- oxygen water," said lead researcher Curtis Deutsch, assistant professor of atmospheric and oceanic sciences at University of California, Los Angeles."There are widespread areas of the ocean where marine life has had to flee or develop very peculiar adaptations to survive in low- oxygen conditions," Deutsch said in the study to be published in an upcoming print edition of the journal Science.A team led byDeutsch used a specialized computer simulation to demonstrate for the first time that fluctuations in climate can drastically affect the habitability of marine ecosystems.The study also showed that in addition to consuming oxygen, marine bacteria are causing the depletion of nitrogen, an essential nutrient necessary for the survival of most types of algae."We found there is a mechanism that connects climate and its effect on oxygen to the removal of nitrogen from the ocean," Deutsch said. "Our climate acts to change the total amount of nutrients in the ocean over the timescale of decades."Low-oxygen zones are created by bacteria living in the deeper layers of the ocean that consume oxygen by feeding on dead algae that settle from the surface. Just as mountain climbers might feel adverse effects at high altitudes from a lack of air, marine animals that require oxygen to breathe find it difficult or impossible to live in these oxygen-depleted environments, Deutsch said.Sea surface temperatures vary over the course of decades through a climate pattern called the Pacific Decadal Oscillation, during which small changes in depth occur for existing low-oxygen regions, Deutsch said. Low-oxygen regions that rise to warmer, shallower waters expand as bacteria become more active; regions that sink to colder, deeper waters shrink as the bacteria become more sluggish, as if placed in a refrigerator."We have shown for the first time that these low-oxygen regions are intrinsically very sensitive to small changes in climate," Deutsch said in remarks published Friday by the American Association for the Advancement of Science on its website. "That is what makes the growth and shrinkage of these low-oxygen regions so dramatic."Molecular oxygen from the atmosphere dissolves in sea water at the surface and is transported to deeper levels by ocean circulation currents, where it is consumed by bacteria, Deutsch said."The oxygen consumed by bacteria within the deeper layers of the ocean is replaced by water circulating through the ocean," he said. "The water is constantly stirring itself up, allowing the deeper parts to occasionally take a breath from the atmosphere."A lack of oxygen is not the only thing fish and other marine life must contend with, according to Deutsch. When oxygen is very low, the bacteria will begin to consume nitrogen, one of the most important nutrients that sustain marine life."Almost all algae, the very base of the food chain, use nitrogen to stay alive," Deutsch said. "As these low-oxygen regions expand and contract, the amount of nutrients available to keep the algae alive at the surface of the ocean goes up and down. "Understanding the causes of oxygen and nitrogen depletion in the ocean is important for determining the effect on fisheries and fish populations, he said.

WASHINGTON, Aug. 11 (Xinhua) -- The unique fossils of an adult plesiosaur and its unborn baby may provide the first evidence that these ancient animals gave live birth like mammals, according to a new study to be published Friday in the journal Science.The 78-million-year-old, 15.4-foot-long (4.7-meter-long) adult specimen is a Polycotylus latippinus, one of the giant, carnivorous, four-flippered reptiles that lived during the Mesozoic Era.Dr. Robin O'Keefe of Marshall University in West Virginia and Dr. Luis Chiappe, Dinosaur Institute director of the Natural History Museum in Los Angeles County, have determined that it is the fossil of an embryonic marine reptile contained within the fossil of its mother.The embryonic skeleton contained within shows much of the developing body, including ribs, 20 vertebrae, shoulders, hips, and paddle bones.O'Keefe and Chiappe have also determined that plesiosaurs were unique among aquatic reptiles in giving birth to a single, large offspring, and that they may have lived in social groups and engaged in parental care.Although live birth has been documented in several other groups of Mesozoic aquatic reptiles, no previous evidence of it has been found in the important order of plesiosaurs."Scientists have long known that the bodies of plesiosaurs were not well suited to climbing onto land and laying eggs in a nest," O'Keefe said."So the lack of evidence of live birth in plesiosaurs has been puzzling. This fossil documents live birth in plesiosaurs for the first time, and so finally resolves this mystery."

WASHINGTON, Aug. 18 (Xinhua) -- Using integrated radar observations from a consortium of international satellites, NASA-funded researchers have created the first complete map of the speed and direction of ice flow in Antarctica, the U.S. National Aeronautics and Space Administration (NASA) announced Thursday.The map, which shows glaciers flowing thousands of miles from the continent's deep interior to its coast, will be critical for tracking future sea-level increases from climate change."This is like seeing a map of all the oceans' currents for the first time. It's a game changer for glaciology," said Eric Rignot of NASA's Jet Propulsion Laboratory and the University of California (UC), Irvine. Rignot is lead author of a paper about the ice flow published online Thursday in Science Express. "We are seeing amazing flows from the heart of the continent that had never been described before."Rignot and UC Irvine scientists used billions of data points captured by European, Japanese and Canadian satellites to weed out cloud cover, solar glare and land features masking the glaciers. With the aid of NASA technology, the team painstakingly pieced together the shape and velocity of glacial formations, including the previously uncharted East Antarctica, which comprises 77 percent of the continent.Like viewing a completed jigsaw puzzle, the scientists were surprised when they stood back and took in the full picture. They discovered a new ridge splitting the 5.4-million-square-mile landmass from east to west.The team also found unnamed formations moving up to 800 feet annually across immense plains sloping toward the Antarctic Ocean and in a different manner than past models of ice migration."The map points out something fundamentally new: that ice moves by slipping along the ground it rests on," said Thomas Wagner, NASA's cryospheric program scientist in Washington. "That's critical knowledge for predicting future sea level rise. It means that if we lose ice at the coasts from the warming ocean, we open the tap to massive amounts of ice in the interior."