济南阴囊湿疹的症状和图片(济南射精血什么原因) (今日更新中)

WASHINGTON, Oct. 13 (Xinhua) -- U.S. researchers have corrected sickle cell disease in adult laboratory mice that had been bred to have the inherited blood disorder by activating production of a special blood component, according to a study published online Thursday in the journal Science.Sickle cell disease results from an abnormality in hemoglobin, the protein found in red blood cells that is responsible for transporting oxygen throughout the body. People living with sickle cell disease have two copies of an altered gene that produces sickle hemoglobin instead of normal adult hemoglobin. Sickle hemoglobin changes shape after releasing its oxygen, causing the red blood cell to become stiff, misshapen and sticky, and slowing blood flow to tissues. This process damages organs and causes pain.The study tested a new approach to increasing the production of a third form of hemoglobin -- fetal hemoglobin. Production of fetal hemoglobin predominates before birth, but turns off thereafter as adult hemoglobin production takes over. People with sickle cell disease are unable to make normal adult hemoglobin, and instead make sickle hemoglobin starting in infancy.An elevated level of fetal hemoglobin within the red blood cell reduces the tendency of sickle hemoglobin to change the shape of red blood cells. Considerable research has shown that the drug hydroxyurea increases production of fetal hemoglobin and reduces the number of pain crises and other complications of sickle cell disease in adults and children. However, not all patients respond well to hydroxyurea, and adverse side effects are a concern.The current study explores a more targeted approach to increasing fetal hemoglobin production. It builds upon earlier studies that discovered a protein called BCL11A normally suppresses the production of fetal hemoglobin soon after birth. The researchers viewed the BCL11A protein as a target for therapy and decided to see what would happen if they blocked production of the protein.The paper details how the research team silenced the mouse gene that produces the BCL11A protein in mice with sickle cell disease. Silencing the gene turned off production of the BCL11A protein and allowed the adult mice to continue to produce fetal hemoglobin. It appears to have eliminated disease symptoms without affecting other aspects of blood production."This discovery provides an important new target for future therapies in people with sickle cell disease," said Susan Shurin, acting director of the U.S. National Heart, Lung, and Blood Institute, which co-funded the study. "More work is needed before it will be possible to test such therapies in people, but this study demonstrates that the approach works in principle."Approximately 100,000 Americans live with sickle cell disease. It is most prevalent in people of African, Hispanic, Mediterranean, and Middle Eastern descent. There is no widely available cure for sickle cell disease. Bone marrow transplants have cured some patients, but the treatment is not without risk and most patients do not have relatives who can donate compatible and healthy bone marrow to them.

SAN FRANCISCO, Nov. 12 (Xinhua) -- Apple has unveiled a worldwide replacement program for the first-generation iPod nano music player due to overheating battery issues, telling owners to stop using the product and get it replaced for free."Apple has determined that, in very rare cases, the battery in the iPod nano (1st generation) may overheat and pose a safety risk. Affected iPod nanos were sold between September 2005 and December 2006," said Apple in a notice posted late Friday on the support section of its official website.The company said the issue has been traced to a single battery supplier that produced batteries with a manufacturing defect. Since the product is five or six years old now, the likelihood of an incident increases.Owners of iPod nano can check the serial number on the back of the product to see if it is eligible for replacement. Apple promises a replacement unit about six weeks after the company received the affected one.The overheating battery issues of the first generation iPod nano have been known for years. In 2008, Japan's Ministry of Economy, Trade and Industry launched an investigation into Apple after dozens of iPod overheating cases were reported, including several incidents of iPod nanos toasting to the point of catching fire and causing minor burns to owners.Last August, a commuter train in Tokyo was delayed during rush hour when passengers complained of a strong burning smell from an overheating iPod nano that had burst apart.The portable music player also cost Apple a 22.5 million-U.S. dollar settlement in 2009 when a class action lawsuit in California alleged iPod nano is prone to scratches and its alleged defects were not disclosed by the company.

BEIJING, Sept. 30 (Xinhuanet) -- Miners, construction workers and people in hotel and food service industry are most likely to smoke in the U.S., according to new research finding.The finding was contained in a report released Thursday by the U.S. Centers for Disease Control and Prevention (CDC).According to the finding, miners and people in hotel and food service have a cigarette smoking rate of 30 percent, followed closely by construction workers' 29.7 percent.Both rates are much higher than the average smoking rate of 19.6 percent among all U.S. working adults.Workers in the education services industry have the lowest smoking rate, with 9.7 percent, followed by the 10.9 percent of workers in company management, the report said.Low education levels are a factor in high smoking rates, along with poverty and gender, said Ann Malarcher, senior scientific adviser at the CDC."Although some progress has been made in reducing smoking prevalence among working adults," the report wrote, "additional effective employer interventions need to be implemented."Smoking kills an estimated 443,000 each year in the U.S., costing about 193 billion U.S. dollars annually in direct health care expenses and productivity loss.

BEIJING, Nov. 5 (Xinhua) -- Chinese President Hu Jintao's speech at the sixth Group of Twenty (G-20) Summit has drawn positive comments from the international community, which praised the address for proposals for efforts to maintain world economic growth and financial stability.In the speech delivered at the Nov. 3-4 summit in Cannes, France, Hu put forward a package of proposals urging the world's major economies to work together to promote growth and financial stability."It is imperative that we stand on a higher plane, transcend differences on specific issues, move beyond short-term considerations, and jointly seek ways to overcome the crisis and sustain development," Hu told the summit.Chinese President Hu Jintao gives a speech at the Group of Twenty (G20) summit in Cannes, France, Nov. 4, 2011."At this critical moment, the G-20 must work to address the key problems, boost market confidence, defuse risks and meet challenges and promote global economic growth and financial stability," Hu said.Reporting developments at the G-20 summit, the Reuters news agency quoted Hu as saying in the speech: "As the premier forum for international economic cooperation, the G20 must continue to demonstrate the spirit of standing together in times of adversity and pursuing win-win cooperation. At this critical moment, the G20 must work to address the key problems, boost market confidence, defuse risks and meet challenges, and promote global economic growth and financial stability."Reuters also said Hu hopes to send a clear message of ensuring economic development and boosting stablity to the international community.The French newspaper Le Figaro reported that Hu expressed confidence that Europe could overcome its debt crisis.The website of Estado de Sao Paulo, Brazil's daily newspaper, quoted Hu as saying that China has made contributions to world economic growth, and that an imperative task for the G-20 summit was to maintain economic growth.At the summit, Hu said that a priority for world leaders is to maintain robust economic growth, and called attention to the maintenance of domestic growth in China, which would benefit the world economy, the newspaper reported.The newspaper also cited Hu as calling for advancing reform of the international monetary system in a steady manner, expanding the use of the Special Drawing Rights of the IMF, reforming the SDR currency basket, and building an international reserve currency system with stable value, rule-based issuance and manageable supply.O Globo newspaper of Brazil reported that in the speech, Hu demanded that Western countries stop exerting pressures on emerging economic powers to compel them to appreciate their currencies.The newspaper quoted Hu as saying: "To keep asking emerging markets to revalue their currencies and reduce exports will not lead to balanced growth. On the contrary, it would only plunge the global economy into a 'balanced recession' and make sustainable growth impossible."In a related development, Robert Zoellick, president of the World Bank, issued a statement on the G-20 summit on Friday, saying: "The G-20 today presented an agenda to restore confidence in the global economy through its commitment to reinvigorate growth, create jobs, ensure financial stability, and make globalization more sustainable and inclusive."The global economy is still very much at risk from faltering economies in developing countries, and the Eurozone deal has bought some time, and the challenge is how to use the time, Zoellick said."I believe it would be very useful if the G20 leaders can send a strong signal on follow-through after the Eurozone announcement so as to sustain and build confidence," Zoellick noted.

WASHINGTON, Nov. 11 (Xinhua) -- The U.S. Food and Drug Administration (FDA) on Friday approved HEMACORD, the first licensed hematopoietic progenitor cells-cord cell therapy.HEMACORD is indicated for use in hematopoietic stem cell transplantation procedures in patients with disorders affecting the blood forming system. For example, cord blood transplants have been used to treat patients with certain blood cancers and some inherited metabolic and immune system disorders."The use of cord blood hematopoietic progenitor cell therapy offers potentially life-saving treatment options for patients with these types of disorders," said Karen Midthun, director of FDA's Center for Biologics Evaluation and Research, in a statement.HEMACORD contains hematopoietic progenitor cells (HPCs) from human cord blood. Cord blood is one of three sources of HPCs used in transplants. The other two are bone marrow and peripheral blood. Once these HPCs are infused into patients, the cells migrate to the bone marrow where they divide and mature. When the mature cells move into the bloodstream they can partially or fully restore the number and function of many blood cells, including immune function.

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