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A third leading candidate COVID-19 vaccine has entered a final stage of human testing in the United States. AstraZeneca announced Monday its potential COVID-19 vaccine has entered final trials in the U.S. to test the effectiveness and safety of the product. The Cambridge, England-based company said the trial will involve up to 30,000 adults from various racial, ethnic and geographic groups. The potential vaccine was invented by the University of Oxford and an associated company, Vaccitech.AstraZeneca said development of the vaccine known as AZD1222 is moving ahead globally with late-stage trials in the U.K., Brazil and South Africa. Further trials are planned in Japan and Russia.“To have just one vaccine enter the final stage of trials eight months after discovering a virus would be a remarkable achievement; to have three at that point with more on the way is extraordinary,” Health and Human Services Secretary Alex Azar said in a statement.Two other vaccine candidates began final testing this summer in tens of thousands of people in the U.S. One was created by the National Institutes of Health and manufactured by Moderna Inc., and the other developed by Pfizer Inc. and Germany’s BioNTech. 1215

A Minneapolis police officer was charged Tuesday with third-degree murder in the death of Justine Ruszczyk, a 40-year-old Australian woman who was shot in 2017 after she called 911 to report a possible sexual assault near her home.Officer Mohamed Noor turned himself in to authorities, said Sherral Schmidt of the Police Officers Federation of Minneapolis.Noor is being charged with third-degree murder -- "perpetrating an eminently dangerous act and evincing a depraved mind" -- as well as second-degree manslaughter -- "culpable negligence creating unreasonable risk," according to the Hennepin County Jail website.In July, Ruszczyk called 911 late at night to report a possible sexual assault in an alley near her home. Fewer than 30 minutes later, she was dead from a gunshot wound to the abdomen. One of the two officers who responded to the call shot the unarmed woman.Officer Matthew Harrity told investigators that he drove to the scene and was startled by a "loud sound" near the squad car, according to Minnesota's Bureau of Criminal Apprehension.Immediately afterward, Ruszczyk approached the window on the driver's side, and Noor, Harrity's partner, shot Ruszczyk through the window, Harrity said.Hennepin County Attorney Mike Freeman told reporters on Tuesday afternoon that Noor's actions did not reflect the training he and Harrity received on responding to possible threats to their safety."There is no evidence that Officer Noor encountered a threat, appreciated a threat, investigated a threat or confirmed a threat that justified his decision to use deadly force," Freeman said.The prosecutor said some police officers would not cooperate with the investigation and volunteer information about the incident.Noor's attorney, Tom Plunkett, said Ruszczyk's death "is a tragedy and Officer Noor again personally extends his continued condolences to her family for their loss.""The facts will show that Officer Noor acted as he has been trained and consistent with established departmental policy. Officer Noor should not have been charged with any crime," he said in a statement.Though the officers were wearing body cameras, they did not turn them on before the shooting, and the squad car camera did not capture the incident, investigators said.That lack of video evidence has frustrated city officials and led the Minneapolis Police Department to update its body camera policy to require officers to activate them upon being dispatched.Ruszczyk's death caused outrage in the United States and Australia and led to the resignation of the city's police chief.Though she was a veterinary surgeon in Australia, her native country, Ruszczyk worked as a spiritual healer, yoga and meditation instructor, and life coach in Minnesota.Don Damond, her fiance, said the two had planned to marry later that summer.The Ruszczyk family released a statement, praising the decision to charge Noor, calling it "one step toward justice for this iniquitous act.""We remain hopeful that a strong case will be presented by the prosecutor, backed by verified and detailed forensic evidence, and that this will lead to a conviction," said the statement released through family attorney Robert Bennett."No charges can bring our Justine back. However, justice demands accountability for those responsible for recklessly killing the fellow citizens they are sworn to protect, and today's actions reflect that."The Police Officers Federation of Minneapolis said it could not comment on specifics of the case."We recognize the tragic shooting of Justine (Ruszczyk) Damond has greatly impacted, not only her family and friends, our membership, but also our community. We respect the criminal justice process and wait for the case to proceed before making further comment," the group said.Noor's last day of employment with the force was Tuesday, according to police Chief Medaria Arradondo. The chief said legally he couldn't say whether Noor was fired.Arradondo apologized to Ruszczyk's family and friends."I know that these three words will not bring Justine back but I want you to know that I am deeply saddened and truly sorry for her death and for your tragic loss," he said. 4192

A pro-growth group's sweeping victory this week could smooth the road for more dense housing in San Diego's uptown neighborhoods.The group, Rise Up Town, won all seven open seats on the city's Uptown Planning Group. The all-volunteer board makes official recommendations to the City Council on proposals in Hillcrest, Bankers Hill, Mission Hills and parts of University Heights. Rise Up Town campaigned on "taller, well designed buildings," with support for affordable development, faster approval, and more walkable and bikeable neighborhoods, with lower speed traffic. It also said the current board members weren't doing enough to support growth in a time that San Diego needs it. "We thought that we could address the problems that we saw in terms of housing affordability, in terms of bike and pedestrian infrastructure within the community," said Clint Daniels, one of the newly elected members. "We got together, we were passionate about it, and we thought those passionate ideas that we could serve the community well."About 500 people voted in the election, held Tuesday before the Uptown Planning Group's meeting. The vote unseated three incumbents, including board chair Leo Wilson. Mat Wahlstrom, who lost his bid for re-election, said he's concerned the new members could serve as a rubber stamp for developers. "None of us have said anything against appropriate density," he said. "We definitely don't want to put all of uptown under saran wrap."There are 17 members on the Uptown Planning Group. Another seven seats are up for re-election next year. 1573

A Thanksgiving night shooting at a mall in Alabama left two people injured and a gunman dead, authorities said Thursday.The incident at the Riverchase Galleria in Hoover started with a physical altercation between an 18-year-old and the 21-year-old gunman, police said. The confrontation occurred in the mall, near Footaction and JC Penney stores.Police do not know how the confrontation began, but "we do not believe at this point the 18-year-old was armed," Hoover police Capt. Gregg Rector said.The gunman opened fire, shooting the teen twice in the torso, according to police. An officer confronted the gunman as he ran away from the scene and fatally shot him, Rector said.The officer involved has been placed on administrative leave while the Jefferson County Sheriff's Office investigates the incident, police said.A 12-year-old girl was also struck and injured, but it's unclear by whom, Rector said. The two people injured have been hospitalized.The girl had a single gunshot wound and has gone through surgery and "does not have life-threatening injuries," Rector told CNN.Witnesses described hearing gunshots inside the mall, which was open late on Thanksgiving. The scene was chaotic, with customers screaming and staff working to lock down the shopping center, witnesses told CNN affiliate WBRC.The Hoover Police Department said the scene is now secure.Hoover is about 10 miles from Birmingham.Brookfield Properties, which owns the shopping center, said it was devastated by the shooting."We are working closely with the Hoover Police Department and are grateful for their swift action to contain the situation," spokeswoman Lindsay Kahn said."While there is no current danger to our community, the shopping center will remain closed for tonight." 1768

A recent study from Iowa State University’s Food Science And Human Nutrition Department found that eating cheese could help protect against age-related cognitive problems, and drinking red wine led to cognitive function improvements.According to the study published in November's Journal of Alzheimer's Disease, the team analyzed data from 1,787 adults, who ranged in age from 46 to 77, through the UK Biobank. This biomedical database contains in-depth genetic and health details of 500,000 participants.Between 2006 and 2016, participants completed a Fluid Intelligence Test (FIT) and then were assessed in two follow-up tests that gave an in-time snapshot of the participants' ability to think on the fly.The participants also answered questions about their food and alcohol intake, the study showed.According to the study, researchers found that eating cheese protected the most against age-related cognitive problems. It also showed that drinking alcohol daily, red wine, in particular, was related to improving cognitive function.Researchers also found that eating lamb weekly, but not other red meats, improved long-term cognitive prowess, the study showed.The study also found that eating excessive amounts of salt can cause cognitive problems over time. 1270