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WASHINGTON, Aug. 4 (Xinhua) -- U.S. scientists have found two gene mutations occurring in oligodendrogliomas, the second-most common form of brain cancer, according to a study to be published Friday in journal Science.For years scientists have been looking for the primary cancer genes involved in oligodendrogliomas evolvement. Scientists know the two chromosomes held the probable mutations, but the particular gene information remains unclear.Now scientists at Duke University Medical Center and Johns Hopkins University have discovered the most likely genetic mutations that researchers have been hunting for on chromosomes 1 and 19.The genes they identified, CIC or FUBP1, are tumor suppressor genes. The cancer-related pathways that involve these genes could become targets for future treatments, said Hai Yan, a Duke associate professor of pathology and co-corresponding author of the study.The researchers found CIC on chromosome 19 and FUBP1 on chromosome 1 based on an initial study of seven oligodendrogliomas. They found six mutations and two mutations, respectively, in the seven tumors. Further study of 27 more of these tumors showed that there were 12 and three mutations of CIC and FUBP1, respectively. The two genes were rarely mutated in other types of cancers, indicating that they are oligodendroglioma-specific genes.These genes were difficult to find until the technology improved, said Yan."The team used whole genome sequencing technology so that no genes would be excluded, and we found to our surprise that one gene, on chromosome 19, was mutated in six out of the seven initial tumor specimens we sequenced," Yan said. "A mutation frequency of 85 percent is very high."The finding of two additional new genes involved in oligodendrogliomas increases the chances for an effective combination drug therapy for the tumor, Yan said. He envisions a combination cocktail of drugs similar to the combination-drug treatments taken by HIV patients that would target different pathways involved in cancer, and assist both in reducing the chance of relapsing and increasing odds of success.

SAN FRANCISCO, July 19 (Xinhua) -- Apple Inc. on Tuesday reported strong third fiscal quarter results that top analysts' expectations, citing strong iPhone and iPad sales.For its fiscal 2011 third quarter ended on June 25, Apple reported net income of 7.31 billion U.S. dollars or 7.79 dollars per share, compared with 3.25 billion dollars, or 3.51 dollars per share a year ago.Its revenue reached 28.57 billion dollars, compared with 15.7 billion dollars in the same period a year earlier. International sales accounted for 62 percent of the quarter's revenue.The average estimate is a profit of 5.84 dollars a share on revenue of 24.9 billion dollars.The Cupertino, Califronia-based company sold 20.34 million iPhones in the quarter, representing 142 percent unit growth over the year-ago quarter. It sold 9.25 million iPads in the third quarter, a 183 percent unit increase on a year-over-year basis.The only drawback is the sales of iPods, which had a 20 percent unit decline to 7.54 million from the year-ago quarter."We're thrilled to deliver our best quarter ever, with revenue up 82 percent and profits up 125 percent," Steve Jobs, Apple's chief executive officer, said in a statement."Right now, we're very focused and excited about bringing iOS 5 and iCloud to our users this Fall," added Job.It is the first time since 2008 that Apple's third-quarter earnings does not include the release of a new iPhone, which, slated for launch in September, is reportedly to be thinner and lighter with a faster chip and 8-megapixel camera.Apple has enjoyed double-digit year-over-year percentage revenue growth for the past four quarters. It had previously beaten the average earning projection for at least 29 straight quarters, according to data compiled by Bloomberg.For the fourth fiscal quarter of 2011, Apple's chief financial officer Peter Oppenheimer said the company expects revenue of 25 billion dollars and earnings per share of about 5.5 dollars. Apple has been known for its conservative projections of earnings.Apple has been operating without the daily attention of Jobs since the CEO took a medical leave this January. The Wall Street Journal reported Tuesday that some members of Apple's board have discussed CEO succession with executive recruiters and at least one head of a high-profile technology company.But the people familiar with the matter told the newspaper that it was more of an informal exploration of the company's options and don't appear to have been acting on behalf of the full board.Meanwhile, Apple has recently been busy with a number of legal battles over patent rights with HTC, Eastman Kodak and Samsung.Last week, the U.S. International Trade Commission made an initial ruling that HTC infringed two of Apple's phone patents in its smartphones powered by Google's Android operating system.If upheld, the ruling could let Apple force other Android phone makers to pay significant patent fees.On Tuesday, Google's executive chairman Eric Schmidt said at a conference in Tokyo that Apple's smartphone lawsuits are inspired by jealousy and a lack of innovation in iPhone, noting Google would support HTC's fight against Apple and was confident of a win.

BEIJING, Sept. 27 (Xinhuanet) -- Scientists have been making great efforts to show how harmful coffee is to us, though no evidence yet. A latest study may be reassuring for coffee-lovers.Women who drink caffeinated coffee are less likely to be depressed than those don't. And the more they drink, the lower risk of developing depression, according to a study published Monday in the Archives of Internal Medicine. Researchers of the study tracked the health of over 50,000 women aged between 30 and 55 in 1996 for a decade and recorded their mental health and coffee intake periodically.They find that women who drank two or three cups of coffee per day were 15 percent less likely than those who drank little or decaffeinated coffee to be depressed.And for those who drank four or more cups, the risk of developing depression reduced by 20 percent.The reason why coffee could protect depression is not clear. But the scientists from the Harvard University speculated that caffeine was the key player. More research is needed to show whether caffeine can ward off depression.It might be that not-depressed people tended to be more activated and the habit of coffee drinking just fit in their lifestyle.However, the depressed ones, who might suffer from sleeplessness, chose not to drink coffee because the caffeine might exacerbate it."There's no need to start drinking coffee," said Dr. Alberto Ascherio, the senior author of the study, "The message is that coffee is safe to drink, with no adverse effects. That's really all that can be said."

BEIJING, Aug. 30 (Xinhua) -- China's second moon orbiter, the Chang'e-2, has arrived in outer space about 1.5 million km away from Earth and is now orbiting the second Lagrange Point (L2), where gravity from the sun and Earth balances the orbital motion of a satellite, Chinese scientists said Tuesday.Chang'e-2 entered L2's orbit at 11:27 p.m. last Thursday after spending 77 days traveling away from its previous orbital path around the moon, according to the State Administration of Science, Technology and Industry for National Defence (SASTIND).The SASTIND said that China is now the world's third country or organization to successfully put a spacecraft into orbit around L2, after the European Space Agency (ESA) and the National Aeronautics and Space Administration (NASA) of the United States.The Chang'e-2 orbiter will carry out exploration activities around L2 in the coming year, SASTIND said.There are five so-called "Lagrange Points" about 1.5 million km way from the Earth in the exact opposite direction from the sun. Putting a spacecraft at any of these points allows it to stay in a fixed position relative to the Earth and sun with a minimal amount of energy needed for course correction.The orbiter completed all of its assigned tasks after blasting off on Oct. 1, 2010, according to the SASTIND. Although the orbiter was only supposed to remain in space for six months, the SASTIND decided to assign additional tasks to it, as it still had fuel in its reserve tanks.Traveling into outer space from the moon's orbit was one of the orbiter's most important missions, according to the SASTIND.Before arriving at its current position in outer space, the Chang'e-2 took photos of the northern and southern poles of the moon. It then descended to a lower orbit, approximately 15 km away from the moon's surface, where it captured high-resolution images of the Sinus Iridum, or "Bay of Rainbows," an area where future moon probes may land.The SASTIND is reportedly planning to launch measure and control stations into outer space by the end of the second half of next year. The Chang'e-2 will be used to test the two stations' functionality at that time.China's ambitious three-stage moon mission will include a moon landing, as well as the launch of a moon rover during the second stage, which is scheduled to take place in 2012. During the third phase, another rover will land on the moon and return to Earth with lunar soil and stone samples for scientific research around 2017.China does not currently have a timetable in place for a manned moon landing. It launched its first lunar probe, the Chang'e-1, in October 2007.In 2003, China became the third country after Russia and the United States to send a human into space. Two more manned space missions followed, the most recent of which took place in 2008.0 The Chang'e probes are named after the Chinese legendary goddess of the moon.

LOS ANGELES, June 9 (Xinhua) -- The edge of our solar system may not be smooth, but filled with a turbulent sea of magnetic bubbles approximately 100 million miles (160 million kilometers) wide, NASA's Jet Propulsion Laboratory (JPL) said on Thursday.The finding was based on observations from NASA's Voyager spacecraft, humanity's farthest deep space sentinels, said JPL in Pasadena, Los Angeles.While using a new computer model to analyze Voyager data, scientists found the sun's distant magnetic field is made up of bubbles which are created when magnetic field lines reorganize, said JPL.The new model suggests the field lines are broken up into self- contained structures disconnected from the solar magnetic field, according to JPL."The sun's magnetic field extends all the way to the edge of the solar system," said astronomer Merav Opher of Boston University. "Because the sun spins, its magnetic field becomes twisted and wrinkled, a bit like a ballerina's skirt. Far, far away from the sun, where the Voyagers are, the folds of the skirt bunch up."Like Earth, our sun has a magnetic field with a north pole and a south pole. The field lines are stretched outward by the solar wind, a stream of charged particles emanating from the star that interacts with material expelled from others in our corner of the Milky Way galaxy.Understanding the structure of the sun's magnetic field will allow scientists to explain how galactic cosmic rays enter our solar system and help define how the star interacts with the rest of the galaxy.The Voyager spacecraft, more than nine billion miles (14 billion kilometers) away from Earth, are traveling in a boundary region. In that area, the solar wind and magnetic field are affected by material expelled from other stars in our corner of the Milky Way galaxy.Launched in 1977, the Voyager twin spacecraft have been on a 33- year journey. They are en route to reach the edge of interstellar space. JPL built the spacecraft and continues to operate them.