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发布时间: 2025-05-25 23:12:54北京青年报社官方账号
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WELLINGTON, May 24 (Xinhua) -- New Zealand researchers have found a way to stop the growth of certain cancer tumors by " silencing" a group of PAX genes, members of a small family of genes that play important roles in embryonic development, but also allow cancer cells to grow and divide in adult tissue.In an article published in UK medical journal Oncogene, Otago University Professor Michael Eccles and colleagues revealed how they used the PAX8 gene to kill cancer cells.After detecting high levels of PAX8 protein in the majority of kidney, ovarian and thyroid cancers they studied, the researchers used molecular techniques to silence the PAX8 gene in several cancer cell lines."We found that these PAX8-depleted cancer cells ceased growing and dividing. The cells were essentially stopped in their tracks through the failure of multiple mechanisms and pathways crucial to their cell division cycle. They then entered into a state called senescence in which they no longer divided, and after that they ultimately died," Eccles said in a statement from the university Tuesday.The findings suggested that PAX8 could be a good target for the development of new cancer therapies, he said."Any resulting drugs would be a long way down the road, but in the meantime this research helps confirm that a focus on PAX genes may prove to be a fruitful line of attack against a number of cancers," he said.The research was supported by grants from the Health Research Council of New Zealand. It formed the main piece of work carried out by Otago doctoral graduate Caiyun (Grace) Li, now a postdoctoral fellow at Stanford University. Study co-authors also included Professor Antony Braithwaite and master's student Jen Nyman.In 2003, research led by Eccles discovered that proteins from one or more of the nine PAX genes were present in many common cancers. They found that "silencing" the gene expression of PAX2 in ovarian and bladder cancer cells, and of PAX3 in melanoma, led to the rapid death of the cells.

  温州新生儿头颅模型   

BEIJING, Feb. 9 (Xinhua) -- China has introduced new stimulus policies to boost the development of the software and integrated circuit (IC) industries.Software firms will continue to enjoy preferential value-added tax policies, according to a circular posted on the central government's website, www.gov.cn on Wednesday. The circular was dated Jan. 28.The new policies also granted tax cuts to manufacturers of integrated circuit. Enterprises of IC products whose product line is less than 0.8 micron (including 0.8 micron) wide will be exempted from corporate income taxes on the first and the second year after reaching profitability, according to the statement.Taxes will also be halved for such companies from the third to fifth year after reaching profitability.Makers of IC products that have a product line that is less than 0.25 micron wide or have invested more than 8 billion yuan (1.21 billion U.S. dollars) in production will pay reduced income taxes.For companies that have operated for more than 15 years, corporate income taxes will be exempted from the first year to the fifth after reaching profitability.Between the sixth and the tenth year, the firms will pay half of the taxes, the statement said.The government also encouraged consolidation in the software and IC industries and will provide financial support to technological research and development.

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BEIJING, Feb. 1 (Xinhua) -- Two Air China passenger planes carrying 457 Chinese citizens stranded in Egypt are due to arrive in Beijing early morning on Wednesday.The planes took off from the Cairo International Airport respectively at 11:16 and 15:32 local time (0916 and 1332 GMT) on Tuesday.The Civil Aviation Administration of China (CAAC), the nation's aviation authority, said Tuesday it was doing its best to organize flights to Egypt to bring home Chinese tourists stranded in the North African nation.China has arranged six flights to fly stranded Chinese nationals home, the CAAC said in a statement posted on its website.

  

SAN FRANCISCO, May 3 (Xinhua) -- Apple Inc. announced on Tuesday that it has updated its iMac all-in-one desktop, adding Intel's next generation quad-core processors, Thunderbolt data ports and a new HD camera.Starting at 1,199 U.S. dollars, the new iMac is up to 70 percent faster and its new graphics deliver up to three times the performance of the previous generation, Apple said in a statement.The new iMac features quad-core Intel Core i5 processors with an upgrade option to Core i7 processors.The 21.5-inch model has a single Thunderbolt port while the 27- inch has two, in addition to four USB 2.0 inputs and a FireWire 800 port.Thunderbolt, which debuted with Apple's updated MacBook Pro notebooks in February, is also an Intel design bringing together high-speed data transfer and high-definition display onto a single cable. It can transfer a full-length HD movie in less than 30 seconds with a speed of 10 gigabits per second, which is twice the speed of USB 3.0, 12 times faster than FireWire 800 and up to 20 times faster than USB 2.0.The new iMac also includes a built-in FaceTime HD camera, which supports high-definition video calls, Apple said.

  

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