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WASHINGTON, April 25 (Xinhua) -- A class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University of Michigan Comprehensive Cancer Center finds.Working in cell lines from colorectal cancer patients, researchers found that the class of drugs called PARP inhibitors worked against tumors with mutations in the MRE11 gene.About 15 percent of all colorectal cancers have what's called microsatellite instability, a type of error in the DNA. About 82 percent of those tumors have the MRE11 gene mutation."This is a potential broader application for PARP inhibitors, beyond breast and ovarian cancer. This is a class of drug that's already shown safety in early clinical trials and now might benefit some colorectal cancer patients as well," says lead study author Eduardo Vilar-Sanchez, a hematology/oncology fellow at the university, in a statement.The study, which was published Monday in Cancer Research, also found that PARP inhibitors are even more effective when both copies of MRE11 were mutated. Each person carries two copies of each gene, which means mutations can occur in either one or both copies. The researchers suggest that PARP inhibitors could be targeted specifically to colorectal cancer patients who have two copies of the mutated gene.Researchers are planning a phase I clinical trial to look at using PARP inhibitors in colorectal cancer patients with two mutated copies of MRE11. Future trials are being considered using PARP inhibitors to prevent colorectal cancer and other cancers in people with Lynch syndrome whose tumors have this mutation.Microsatellite instability is also seen in prostate cancer and endometrial cancer, suggesting potential for PARP inhibitors to play a role in additional types of cancer as well, Vilar-Sanchez says, adding that more research is needed in these areas.

SAN FRANCISCO, May 26 (Xinhua) -- Internet advertising revenues in the United States surged to 7.3 billion U.S. dollars in the first quarter of 2011, the highest first-quarter revenue level on record for the industry, said a new report released on Thursday.The numbers also represented a 23-percent increase over the same period a year earlier, the Interactive Advertising Bureau ( IAB) and PricewaterhouseCoopers said in the report."The consistent and considerable year-over-year growth we're seeing demonstrates that digital media is an increasingly popular destination for ad dollars, and for good reason," Randall Rothenberg, chief executive officer of the IAB, said in a statement."As Americans spend more time online for information and entertainment purposes, digital advertising and marketing has emerged as one of the most effective tools businesses have to attract and retain customers," he added."These numbers indicate that the interactive advertising field hasn't simply bounced back since the recession; it's growing with dynamic energy," noted David Silverman, a partner at PricewaterhouseCoopers.IAB, a trade association for interactive marketing, comprised more than 500 media and technology companies who are responsible for selling 86 percent of online advertising in the United States.

BEIJING, Feb. 26 (Xinhua) -- Zhu Guangya, who contributed to the development of China's first atom and hydrogen bombs, died Saturday at age 87.Zhu was a senior academician at the Chinese Academy of Sciences and the Chinese Academy of Engineering. He served as vice chairman of the National Committee of the Chinese People's Political Consultative Conference, China's top political advisory body, between 1994 and 2003.Born in central China's Yichang city, Zhu obtained a PhD in nuclear physics from the University of Michigan in 1950. That year he returned to China. He joined the Communist Party of China in 1956.

BEIJING, May 24 (Xinhuanet) -- Facebook founder Mark Zuckerberg welcomed more kids to join in the social network site, according to International Business Times reports on Monday.He made this comment in the NewSchools Summit in California.Zuckerberg said Facebood can help young kids to learn from each other and acquire more knowledge about using the internet."That will be a fight we take on at some point," Zuckerberg said, "My philosophy is that for education you need to start at a really, really young age." At the moment, Facebook officially does not allow the children younger than 13 to sign up, since the Children's Online Privacy Protection Act (COPPA) forbids children under 13 from joining an online service which collects user information data.However it recently revealed that 7.5 million Facebook users were younger than that, accoding to a study released last week by Consumer Reports.Some experts suggested Facebook may not be in any position to provide that education in its current form. "The lessons of digital citizenship have to start young, but I don't feel that Facebook is the venue to have those lessons occur. A lot of missteps happen on that site without a lot of coaching." said Dr. Gwenn O'Keeffe, an expert on young children's education.

BEIJING, March 10 (Xinhuanet) -- Cigarette displays in shops will be banned and tobacco companies may also be forced to make their products in plain wrappers in an attempt to stop people from smoking, announced the UK government Thursday.The prominent displays and attractive packaging of tobacco have long provided shopkeepers with stable income, keeping addicts hooked and quitters tempted.However, the government's move that will begin as early as spring next year will keep cigarettes hidden away and make it just a tad more difficult for smokers to find their fix."Nearly all adult smokers started smoking before they turned 18 and every year, over 300,000 children under 16 try smoking," said Chief Medical Officer Sally Davies."Smoking is undeniably one of the biggest and most stubborn challenges in public health. Over eight million people in England still smoke and it causes more than 80,000 deaths each year," Health Secretary Andrew Lansley said in his statement on the new law.Now, this move has drawn predictable responses from both sides of the tobacco wars, with health groups cheering and retailers grumbling.The British Medical Association said it was "very pleased" with the announcement, citing research which it said showed that a display ban would play "a key role in discouraging children from smoking and also help smokers quit."On the other hand, industry groups and independent retailers complained it would burden them with the cost of refitting their stores and reduce their already narrow profit margins.And according to media interviews, many people kept skeptical about the real impact the move would have, especially on young smokers.

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