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SAN DIEGO (CNS) - A COVID-19 vaccine trial sponsored by drugmaker Johnson & Johnson is slated to get underway soon in San Diego, and will include an estimated 2,000 participants at UC San Diego Health, it was announced Thursday.Up to 60,000 participants will be recruited from 10 different countries around the world as the San Diego portion of the trial, dubbed ENSEMBLE, gets underway Oct. 7, according to UCSD.The efficacy, safety and immunogenicity of the drug Ad.26-COV2.S will be tested via a randomized, double-blind, placebo-controlled study, in which half of the participants receive a single-dose injection of the vaccine and the other half receive a placebo. All participants -- who must be 18 years of age or older and in reasonably good health -- will be monitored for signs of infection and COVID-19 over the next two years, according to UCSD.Researchers are particularly interested in recruiting participants at increased risk of SARS-CoV-2 infection due to where they live, their age or personal circumstances, such as working in essential jobs like first responders, health care, maintenance, construction, grocery stores or assisted living facilities.The San Diego trial will also emphasize participation from the region's underserved communities, as communities of color have shown higher rates of COVID-19-related hospitalization and/or death.UCSD cited data from the county showing measurably higher infection rates in the South Bay, including in Chula Vista, Imperial Beach and National City.Susan Little, professor of medicine at UC San Diego School of Medicine and principal investigator of the UC San Diego trial, said, "Many communities of color are experiencing higher rates of hospitalization related to COVID-19 than are observed in white, non-Hispanic people. It is important that these communities are represented in COVID-19 vaccine clinical trials so that we understand if the vaccine will work well within these groups."For more information about participating in the trial at UC San Diego, go to www.covidvaccinesd.com or call 619-742-0433. 2087

SAN DIEGO (AP) -- AJ Pollock hit a pinch, go-ahead double in the seventh inning and added a solo homer, and Dustin May struck out a career-high eight to help the Los Angeles Dodgers beat the San Diego Padres 5-2.Mookie Betts entered the game in right field in the eighth inning after missing a 5-4 loss in the series opener due to a finger injury.May improved to 1-0 by getting his first career win against San Diego. He made his MLB debut against the Padres on Aug. 2, 2019.He held San Diego to three hits and two runs in six innings, with one walk.The Padres took an early 2-0 lead thanks to Jake Cronenworth's first MLB home run and an RBI double by Fernando Tatis Jr.However, Friar errors and two-out rallies led to five unanswered Dodger runs.Kenley Jansen finished off the Padres in the ninth to pick up his third save of the season. 847

SAN DIEGO — The County Office of Education is taking its annual job fair entirely online, with already more than 800 registered job seekers. The job fair, which is regularly held at Liberty Station, will instead feature virtual lobbies and virtual tables. Dr. Sheiveh Jones, who organized the fair for the office of education, said more than 25 school districts and charter schools are participating. She said there may not be as many openings as in prior years because of temporary budget uncertainty, but that could change by the end of the summer. "When a position does open, the district may invite you to apply or they may just recognize your name when they look at the applications," she said. Jones said the districts are hiring for both academic and non-academic positions. She added there is always demand for bilingual, special education, STEM and substitute teachers. She said her best advice is to check out the posted jobs online ahead of time at Edjoin, so jobseekers can be better prepared to meet hiring managers, or even apply before the fair. The event begins at 3 p.m. Tuesday and lasts for three hours. 1131

Sadly, my lovely client lost his brave fight against Oesophageal cancer last week. A fantastic man with a love of baking that saw him get to the finals of GBBO, write a wonderful book, Bake It Great and do so much more. Always in our thoughts.https://t.co/S61Zgm3Vms— Anne Kibel (@AKAManagement) November 3, 2020 325

SAN DIEGO (CNS) - A class-action lawsuit has been filed against Legoland and its parent company for allegedly not providing refunds after the Carlsbad theme park was closed to the public due to the COVID-19 pandemic.The suit was filed Monday in San Diego federal court on behalf of Los Angeles County resident Joyce Case against Merlin Entertainments Limited, which operates Legoland, Tussauds Hollywood, Tussauds San Francisco, the San Francisco Dungeon and Legoland Florida.The suit alleges Case purchased tickets to Legoland for a March 21 trip and ended up "one of the many consumers stuck with tickets to a canceled event who has been unable to obtain a refund," according to the complaint.Legoland representatives could not immediately be reached for comment.RELATED:San Diego Zoo hopes to reopen in 'coming weeks' under new limitsSan Diego cleared to reopen zoos, gyms, bars and wineries, day campsSan Diego theme parks aim for July 1 reopeningThe suit seeks refunds for all customers who paid for tickets, memberships and vacation packages that have since been canceled due to COVID- 19, and damages to compensate customers "for the loss of use of their money during a time when cash is at a premium for the many families targeted by Defendants that are struggling to get by."The complaint states that the terms and conditions of agreements to purchase tickets to Legoland and other Merlin Entertainments Parks hold that if events are canceled, refunds must be paid."Closing of these venues, and cancellation of these events, should have meant that ticketholders were promptly refunded their money -- money that in many cases was very much needed for other purposes," the complaint states. "But that did not happen for customers, who bought tickets, memberships, and vacation packages for Defendants' attractions. Instead, Defendants failed to honor and perform their duties, responsibilities, and obligations under their uniform standardized agreements with their customers, thereby breaching their contracts, but nonetheless pocketed their customers' money and converted it for their own use."A similar class-action lawsuit was filed against SeaWorld last month in San Diego federal court. In that suit, SeaWorld is accused of continuing to charge monthly membership fees to customers during the park's closure. 2329