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2025-05-26 09:15:28
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  巢湖足解剖模型   

CORONADO, Calif. (KGTV) -- The Hotel del Coronado is suspending hotel operations amid the coronavirus outbreak, the Coronado Times reports. According to the times, the temporary suspension will go into effect Thursday, March 26. The hotel told the Times that security will be on-site around the clock to ensure the protection of the historic site. Harold Rapoza, Jr., general manager of Hotel del Coronado & Beach Village at The Del, said in a statement: "This difficult decision is reflective of the current business environment and not a result of illness or confirmed cases at the hotel."RELATED STORIES: California COVID-19 Tracker: 392 positive casesSan Diego COVID-19 Tracker: County reports second deathWe're Open: List your business in our databaseThe Hotel del first opened in 1888 as an "architectural masterpiece."The closure marks the first time the hotel has shut its doors in its 132-year history, according to the Coronado Times.Rapoza said the company was in the process of supporting employees through the transition and notifying guests. Guests with reservations were asked to contact Hilton Reservations and Customer Care, Rapoza said.Construction projects at the hotel would continue "to the extent permitted" by Gov. Gavin Newsom's statewide stay-at-home order along with thehealth and safety policies of the hotel's general contractor, Rapoza said.The announcement comes as 277 San Diego County residents tested positive for COVID-19 as of Wednesday afternoon. So far, two San Diegans have died due to the virus. City News Service contributed to this report 1592

  巢湖足解剖模型   

Costco says they are no longer selling their half-sheet cakes at U.S. clubs.In a statement to E.W. Scripps, the company said they have no immediate plans to bring them back."We are focusing on our smaller 10" white and 10" chocolate cakes that seem to be resonating with our members," the company said in the statement.According to Bloomberg, free samples returned to 30 stores across 16 states. The samples are packaged and kept behind a plexiglass shield, Bloomberg reported. 485

  巢湖足解剖模型   

Could the no-calorie sweetener you rely on to replace sugar in your diet actually cause weight gain instead of the weight loss you were expecting?The answer may be yes, according to a new study."Artificial sweeteners are not risk-free," said Brian Hoffmann, assistant professor in the Department of Biomedical Engineering at the Medical College of Wisconsin and Marquette University, and a lead author of the study. "They are a very controversial topic when it comes to health and nutrition ... but they're so prevalent in society that I think we owe it to ourselves to try and figure out what's actually going on."Hoffmann presented his new research Sunday at the annual?Experimental Biology meeting in San Diego. Relying on rats and human cell cultures, his team identified a number of pathways linking artificial sweeteners with metabolic changes at the genetic level that could lead to diabetes and obesity. Specifically, the researchers found that three weeks of exposure to aspartame and acesulfame potassium -- two artificial sweeteners frequently combined in products such as Equal -- altered the expression of certain genes responsible for lipid metabolism in the cells of both rats and humans."Aspartame had some significant changes, and one of those was an increase in lipids in the bloodstream and a decrease in a biomolecule that is involved in clearing (lipids) from the bloodstream. And we saw the exact same thing with the acesulfame potassium," Hoffmann said."We then took those particular sweeteners and put them on endothelial cells -- the cells that line the blood vessels and would be exposed to them in the body -- and we detected a marked dysfunction, suggesting why sweeteners and diet soda have been linked to potential cardiovascular problems," he added.What was perhaps most surprising, according to Hoffmann, was that these metabolic changes did not occur in the presence of natural sugars such as glucose and fructose. This suggests that artificial sweeteners could contribute to metabolic disorders such as diabetes and obesity by an entirely different mechanism than natural sugars, he said.Artificial sweeteners appear to contribute to metabolic disorders by altering the activity of certain genes responsible for the breakdown of macromolecules such as fats and proteins, Hoffmann said. This is different from normal sugars, which contribute to cardiovascular disease through insulin resistance and by damaging the cells lining the body's blood vessels."People are generally consuming non-nutritive sweeteners believing they are a 'healthy choice,' but this may not be true," said research scientist Meghan Azad of the University of Manitoba in Winnipeg, who was not involved in the new study."This is especially important given the widespread and increasing consumption of artificial sweeteners in the general population and the increasing use of artificial sweeteners in our food supply," said Azad, who has authored a paper that reviewed a number of studies on the potential downside of artificial sweeteners on weight and health.According to Azad, over 40% of adult Americans consume no-cal sweeteners on a daily basis, and studies that measure the sweeteners in blood and urine show that many people who report not using artificial sweeteners are unknowingly consuming them.It's the latest assault in the ongoing debate over artificial sweeteners and their impact on health -- a debate that began when one of our most popular foods, sugar, turned sour in terms of health. 3527

  

COCKEYSVILLE, Md. — A Maryland man is facing more than two dozen criminal charges after stealing a dump truck while drunk and on drugs, fleeing from police, and killing a man during the chase.The incident reportedly began about 2 p.m. Monday when Baltimore City Police contacted Maryland State Police about a stolen dump truck headed northbound on I-83.Troopers eventually located the truck, owned by a roofing company, unoccupied in a Walmart parking lot in Cockeysville, Maryland. Police say they set up surveillance to see who had stolen the tuck. A man, later identified as 26-year-old Zackery Haeger, was later seen getting into the truck, at which time police attempted to stop the vehicle, but he refused. Haeger then proceeded to drive towards troopers who were outside of their vehicles, causing them to have to jump out of the way. Driving erratically at a high rate of speed, he continued to flee, leading troopers on a chase that spanned from York Road through Padonia and Cranbrook Road. He was driving down the median lane on York Road when he hit another car at Padonia Road, causing disabling damage to the car. During the pursuit, the stolen Ford F550 dump truck crossed a double yellow line again and collided with another car, an oncoming Nissan at Rossbrooke Circle. Haeger then bailed out of the car and ran away, where he was captured by troopers.Officials say Haeger was taken to Sinai Hospitals for minor injuries where he gave officers a fake name, but a fingerprint check identified the man as Haeger. Records indicate he does not have a drivers license and is now facing a slew of charges including:  1680

  

CUSICK, Wa. – The pandemic is making learning tough on students across the country, but for one Native American school that relies on in-person learning, COVID-19 is threatening the core of its program.It’s a language born in the mountains of northeastern Washington. The language, a special dialect called Salish, is the native language of the Kalispel Indian tribe.“We live in the land along the rivers, we hunt we fish, that’s our way,” said JR Bluff, the language director of the Kalispel Tribe.A crucial piece of living the Kalispel way is speaking the Salish language. “Being connected to the ground, being connected to the world, our environment, the people, being connected to our ancestors, the language can do that. It gives you that identity,” said Bluff.It's an identity that was about to be lost forever. “We have four elders that have the language, they’re it, and so we have to move,” said Bluff.So, each day, JR Bluff works to keep his heritage alive. “We believe we are backed into the corner. We believe we don’t have tomorrow, it has to happen today,” said Bluff.Several years ago, Bluff started an immersion school to pass that language down to the next generation. All of the lessons are in Salish.Students who opt into the daily program come to the Salish school after a few hours at the public school across the street.The immersion school not only meets common core education standards, it gives both students and teachers a deep connection to their roots.“The language is healing. It filled a void I didn’t know I had,” said Jessie Isadore, the Language Program Coordinator. “When the kids have a strong foundation and know who they are and where they come from, they’ll be more successful.”Just when JR and his team saw their language growing strong through the students, the pandemic threatened to take it all away.“Our strength is relationships,” said Bluff. “You need to be in the seat with me.”“If the kids aren’t in the classroom, they’re home doing online learning, it’s not the same as being in the classroom. We lose time and we lose language,” said Isadore.To make sure that doesn’t happen, the school’s teachers are now creating Salish lessons online, something they’ve never done before.“We have not done zoom with our students yet, so that’s going to be a new process this year,” said Isadore.“We’re going to figure it out, and we have to figure it out. If I have to record, and we have to drop off a disc everyday, I’ll do it,” said Bluff.It’ll take the extra effort in a place where WiFi is not reliable and instruction is best done in person.“Our language, it’s a sacred breath, you’re not just hearing a word, you are with me and you’re hearing my breath, that’s the strength of our language,” said Bluff.While the future of this classroom is left uncertain, the future of this culture is something JR knows he will protect for his entire life.“Our language has had so many bumps in its thousand-year history, this is just another bump. It’s real in that it affects our community, affects our students, affects our parents, but I know it will pass,” said Bluff. 3111

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