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It’s a change Melaine Grein could feel in her joints even before the snow began to fall.“I can feel it in my ankle and I know the weather is going to change before it even does just because it hurts. It’s really stiff,” Grein said.Grein hurt her ankle a couple of years ago and says she’s been able to feel temperature changes in it ever since.“It’s just affected by the weather, cold, rain, everything,” she said. “I’ve told my friend before that I think it’s going to rain and then it did.”Grein isn’t the only one who says she can feel the weather change. Many people with arthritis pain say they can feel it in their joints or bones.At Englewood Primary Care in the Swedish Medical Center, Dr. Scott Joy says it isn’t an urban myth when people say they can feel the weather change.“Big changes in temperature can change blood flow through the body,” Joy said. “Any time we get a large weather system moving through the area it changes the pressure, and people who have chronic joint pain will often notice more joint pain.”A big temperature change can affect three groups of people in particular: those with heart disease, asthma or arthritis. The weather can pose serious health risks for all three groups, which is why Joy says it’s important to be prepared.For people with heart disease, it’s important to have all of your medications on hand and to take them as prescribed. Joy says it’s also a good idea to have some nitroglycerin on hand.If people experience pain in their chest or shortness of breath with the weather change, it’s important to seek medical help.“These are things that can actually lead to death and serious morbidity and mortality. It can lead to unnecessary ER visits, it can lead to long hospital stays, it can even lead to stays in the intensive care unit if you have a severe event,” Joy said.For people with asthma, along with having their chronic inhaler on hand, it’s important to keep a rescue inhaler nearby since the weather change can trigger some inflammation in the upper airways.For those with chronic joint pain, it’s important to have an anti-inflammatory on hand in case the temperature change causes pain.For everyone else, it’s important to bundle up and protect your skin.“You are at real risk for skin damage and dry skin and frostbite,” Joy said.As always, Joy says it’s also a good idea to stay hydrated as well and don’t overexert yourself.This story was originally published by 2433

“I’ve filmed in at least 40 countries; I’ve traveled to 60,” Colburn said. She’s a San Diego native, but she now lives in Istria, Croatia – a place not too far from Italy. When the global coronavirus craziness started in early March, her schedule – which is usually planned a year in advance – was changing by the day. “Things were starting to get canceled left and right," Colburn said. "I had no more projects. And then I remember waking up one morning and I had a text from my mom and it was right after the travel ban was mentioned from Europe and so it was kind of a sudden shock – wait do I come home, is everything going to get canceled – there was just so much unknown. But I didn’t want to get trapped doing nothing in an apartment in Europe where you can’t leave, you know, because this is what was happening in Italy.” So, she flew home to California and isolated herself with family. Normally at this time she’d be traveling from one country to the next filming TV shows, but like the rest of the world, Ashley has been forced to stay put and shelter-in-place. She’s now been in San Diego for 10 weeks and counting. “I’m always on the move. And so, I will say that there are always those to-do lists.” Since her travel itch hasn’t gone away, she feels like it’s her responsibility to keep people connected to the rest of the world when they can’t travel. “We just have to be creative now as travelers and come up with other ways of sharing the world with people and inspiring them to still travel one day,” Colburn said. She’s inspiring people through 1568

-- and its wider implications for human mental health treatment -- was found in their poop, per new findings published in Behavioural Brain Research.Rats are better drivers when they're mentally stimulatedKelly Lambert, study author and head of the University of Richmond's Lambert Behavioral Neuroscience Laboratory, trained two groups of young rats: One bunch raised in an "enriched environment" with toys, ladders, balls and pieces of wood designed to spark mental stimulation, and another reared in a standard, unexciting lab cage.The rats learned to enter a custom "rat-operated vehicle," or ROV, adorably constructed from a one-gallon plastic container turned on its side.Once inside, the rat racers would stand on an aluminum plate and press on a copper bar that would trigger the wheels' motor. They'd hold down on the bar until they propelled their tiny car to the end of their enclosure, where they collected their reward: Froot Loops.When it came time to drive, the rats who played with ladders, balls and toys were more adept at operating and steering the ROV, thanks to the neuroplasticity (their brains' ability to change over time) triggered by their environment. Their unstimulated cage counterparts effectively "failed their driving test," Lambert said.Hormones found in their feces showed improved emotional resilienceIn sifting through their fecal matter, Lambert found both groups of rats trained to drive secreted higher levels of corticosterone and DHEA, hormones that control stress responses.Corticosterone is a hormone animals could secrete in high-stakes scenarios like running from a wild animal or defending themselves from predators, but it can also be expressed in lower-risk tasks like doing taxes or worrying about a loved one (though rats likely aren't advanced enough to form a government, let alone impose taxes on fellow rats).DHEA acts as a sort of "buffer," Lambert said, when corticosterone becomes toxic -- that is, when it can't be turned off in a reasonable amount of time, creating prolonged stress.It's evidence that mastering a complex task, like driving a car, bolstered the rats' emotional resilience."It is likely that driving gives the rats a sense of control over their environment," she said. "In humans, we would say that it enhances a sense of agency or self-efficacy."What have rats got to do with human health?The brains of humans and rats share nearly all of the same areas and neurochemicals -- they're just smaller in rodents. And though humans are certainly more complex than rats, Lambert said there are "universal truths" in how both species' brains interact within their environment to maintain optimal mental health.So these results have implications for human health, too (and no, they don't mean rats will drive alongside people in tiny lanes on highways). Emotional resilience is one of the first lines of defense against mental illnesses like depression, she said, and learning what behaviors build that up could clue physicians in on how to treat those illnesses in humans.It's a concept Lambert refers to as "behaviorceuticals," activities that release hormones that can ward off prolonged stress brought on by corticosterone."Anything that reduces stress can build resilience against the onset of mental illness," she said.The activity can be something as simple as knitting, or in rats' case, learning to drive a car. Just engaging hands, paws and brains of varying sizes can enhance a participant's sense of control. 3489

on Friday afternoon, leaving customers without access to online accounts or support.The bank said on Twitter it was experiencing technical issues with its online services.“We are working as quickly as possible to restore service for our affected customers, and we apologize for the inconvenience," the bank wrote Friday afternoon.It is unclear when the network will be back online. A Fifth Third spokesperson did not immediately respond to a request for comment. 464

While the most likely scenario shows decreased activity, there is still a chance of another major earthquake striking in the next seven days.“According to our forecast, over the [next week,] there is a 4 percent chance of one or more aftershocks that are larger than magnitude 6.4,” the USGS said. “It is likely that there will be smaller earthquakes over the [next week,] with 40 to 230 magnitude-3 or higher aftershocks. Magnitude 3 and above are large enough to be felt near the epicenter. The number of aftershocks will drop off over time, but a large aftershock can increase the numbers again, temporarily.”The uncertainty in the ground below their feet has thousands of Puerto Ricans sleeping outside.“We don’t know if there is going to be any other quake big enough to do additional damage or bigger than what we’ve seen so far,” said Jochen Braunmiller, a seismologist and research faculty member at the University of South Florida.“I was a little surprised about the actual location of those earthquakes because they are not happening right at the plate boundary between the North American and the Caribbean plate,” Braunmiller said. “They are happening close to the island and above the plate boundary.”Braunmiller said the quakes are hitting in a deformed zone near the upper crust. If the location of the earthquake changes, it could be catastrophic for the island.“The worst-case scenario for Puerto Rico would be a subduction zone earthquake on the order of magnitude 7.5 or 8,” Braunmiller said. “I don’t think from historical data earthquakes have been much bigger than that. It would take out a lot of infrastructure for Puerto Rico for quite a while.”The USGS is continually updating their forecast 1720