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BEIJING, May 10 (Xinhuanet) -- Autism spectrum disorder may be under diagnosed and under reported worldwide and rigorous screening is needed for accurate estimates, said researchers in Monday's American Journal of Psychiatry.Researchers from the Yale Child Study Center, George Washington University and other leading institutions screened every child aged 7 to 12 in Ilsan district of the city of Goyang, a community of 488,590 in South Korea, and found more than two-thirds of ASD cases in the mainstream school population unrecognized and untreated.They estimated the prevalence of ASD in South Korea to be 2.64 percent, or approximately 1 in 38 children.The figure is more than twice the rate usually reported in the developed world. Even that rate, about 1 percent, has been climbing rapidly in recent years — from 0.6 percent in the United States in 2007, for example.“From the get-go we had the feeling that we would find a higher prevalence than other studies because we were looking at an understudied population: children in regular schools,” said the lead researcher, Dr. Young-Shin Kim, a child psychiatrist and epidemiologist at the Yale Child Study Center.By contrast, other research groups measure autism prevalence by examining and verifying records of existing cases kept by health care and special education agencies, but leaving out many children whose parents and schools have never sought a diagnosis.Kim said the researchers concluded autism prevalence estimates worldwide may increase if rigorous screening and comprehensive population studies are used to produce prevalence estimates.But it is suggested the findings did not mean that the actual numbers of children with autism were rising, simply that the study was more comprehensive than previous ones.

BEIJING, Feb. 6 (Xinhua) -- Chinese Vice Premier Hui Liangyu on Sunday urged local authorities to intensify efforts to prevent forest fires.The senior Chinese official also ordered the country's forest fire prevention departments to come up with emergency response measures to be implemented as soon as fires break out.Hui warned that the country faced severe challenges from forest fires as the drought in the north continued and there was less rain than normal in the south in February.A total of 168 forest fires were recorded from Feb. 2 to Feb. 6, according to monitoring stations from the country's forest fire management authority.On Saturday, a forest blaze killed six people and left another three injured in east China's Zhejiang Province. Local officials said fireworks were the likely cause of the tragedy.
WUHAN, Feb. 8 (Xinhua) -- Ten people were comfirmed dead and nine others injured when a farmer's tricycle rolled over into an 8-meter deep gully at about 2:30 p.m. Monday at a village in Lichuan City, Hubei province.Eight passengers were found dead on the spot. The eleven wounded were hastened to the hospital. But two of them died on the way.Sources with the Lichuan government said the farmer's vehicle carried the passengers illegally. The rescue operation continued until midnight. The actual cause for accident was still under investigation.
WELLINGTON, May 24 (Xinhua) -- New Zealand researchers have found a way to stop the growth of certain cancer tumors by " silencing" a group of PAX genes, members of a small family of genes that play important roles in embryonic development, but also allow cancer cells to grow and divide in adult tissue.In an article published in UK medical journal Oncogene, Otago University Professor Michael Eccles and colleagues revealed how they used the PAX8 gene to kill cancer cells.After detecting high levels of PAX8 protein in the majority of kidney, ovarian and thyroid cancers they studied, the researchers used molecular techniques to silence the PAX8 gene in several cancer cell lines."We found that these PAX8-depleted cancer cells ceased growing and dividing. The cells were essentially stopped in their tracks through the failure of multiple mechanisms and pathways crucial to their cell division cycle. They then entered into a state called senescence in which they no longer divided, and after that they ultimately died," Eccles said in a statement from the university Tuesday.The findings suggested that PAX8 could be a good target for the development of new cancer therapies, he said."Any resulting drugs would be a long way down the road, but in the meantime this research helps confirm that a focus on PAX genes may prove to be a fruitful line of attack against a number of cancers," he said.The research was supported by grants from the Health Research Council of New Zealand. It formed the main piece of work carried out by Otago doctoral graduate Caiyun (Grace) Li, now a postdoctoral fellow at Stanford University. Study co-authors also included Professor Antony Braithwaite and master's student Jen Nyman.In 2003, research led by Eccles discovered that proteins from one or more of the nine PAX genes were present in many common cancers. They found that "silencing" the gene expression of PAX2 in ovarian and bladder cancer cells, and of PAX3 in melanoma, led to the rapid death of the cells.
来源:资阳报