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Researchers published what they say is the first case of a living person diagnosed with the degenerative brain disease chronic traumatic encephalopathy or CTE.While unnamed in the study, lead author Dr. Bennet Omalu confirmed to CNN that the subject of the case was former NFL player Fred McNeill -- who died in 2015.Omalu is credited with first discovering CTE in professional football players. Until now, the only way to diagnose the disease is with a brain exam after death.The diagnosis was first made using an experimental brain scan that can trace a signature protein of CTE called tau. The authors then confirmed the diagnosis with an autopsy. The case study was published in the journal Neurosurgery this week.'It looked like just depression'Omalu first presented these findings exclusively to CNN's chief medical correspondent, Dr. Sanjay Gupta, in 2016. McNeill's wife, Tia, and his two sons, Gavin and Fred Jr., told Gupta then that they saw Fred transform from a fun loving family man at the center of their lives into a man who was dealing with symptoms of memory loss, anger and depression that tore their family apart."There are some times where the father is the stronghold in the family, or the anchor. If you lose that, everything kind of falls apart. That's kind of what happened for us. It looked like financial issues at first; it looked like marital issues, and they separated; then it looked like just depression," Gavin told Gupta.CTE is known for plaguing people with Alzheimer's like symptoms such as memory loss, rage, mood swings, and in some cases, suicidal ideation.Severity of the disease is categorized into four stages, with stage 4 being the most severe. While researchers don't know exactly why certain people develop the disease and others don't, they believe that it results from repeated blows to the head that trigger a build up of tau proteins in the brain.CTE has been called football's "concussion crisis," however experts point out that CTE can develop from any repeated head injury. According to the Boston University CTE Center, "this trauma includes both concussions that cause symptoms and subconcussive hits to the head that cause no symptoms." These subconcussive hits can include the repeated trauma the brain experiences from constant plays, hitting the turf, and tackling. Wrestlers, boxers, and military troops have also been diagnosed with the disease.Seeing CTEWhile McNeill is the first case to be confirmed with an autopsy, the experimental technology has been used on at least a dozen other former NFL players, including Pro Football Hall of Famer, Dallas Cowboy Tony Dorsett. Omalu helped develop and is invested in the diagnostic exam, which uses a radioactive "tracer" called FDDNP to bind to tau proteins in the brain. The tau proteins can then be seen on a PET scan of the brain.Critics have said the protein also can highlight another protein called amyloid, which may be indicative of Alzheimer's or other forms of dementia. But Omalu noted that in CTE, tau makes distinctive patterns in the brain. It has a "specific topographic signature," he said, and that pattern can be detected in imaging.Omalu said he and his team are currently raising money to start a phase 3 clinical trial to further test the technology and replicate what they have seen in McNeill. He anticipates that once funds are raised, it will take another two to three years for the trial and then another year, at least, for approval from the US Food and Drug Administration. When asked, how soon a commercial test could be available, Omalu predicted it could be as soon as a few years. "We are looking at less than five years," he said. 3711
President Donald Trump's former attorney and "fixer" Michael Cohen said he is "done being loyal" to his former boss and admitted that he knew what he was "doing was wrong" when he arranged payments during the 2016 election to silence women who claimed to have had affairs with Trump."I'm done with the lying," Cohen said in an interview with ABC News' George Stephanopoulos that aired Friday. "I'm done being loyal to President Trump. My first loyalty belongs to my wife, my daughter, my son and this country."Reiterating what he said in his guilty plea in August, Cohen told ABC News that Trump directed him to make the payments because Trump "was very concerned about how this would affect the election."Asked whether Trump knew it was wrong, Cohen replied, "Of course.""I knew what I was doing was wrong," Cohen said. "I stood up before the world (Wednesday) and I accepted the responsibility for my actions."Asked why he should be believed, Cohen replied, "Because the special counsel stated emphatically that the information that I gave to them is credible and helpful. There's a substantial amount of information that they possess that corroborates the fact that I am telling the truth."President Trump said in an interview with Fox News Thursday that he "never directed (Cohen) to do anything wrong.""I don't think there's anybody that believes that," Cohen told ABC News of Trump's denials. "First of all, nothing at the Trump organization was ever done unless it was run through Mr. Trump."The president's former fixer -- who once said he'd "take a bullet" for Trump -- told ABC he "gave loyalty to someone who truthfully does not deserve loyalty" and that he "should not be the only one taking responsibility for his actions.""So, (Trump's) still lying?" Stephanopoulos asked."Yes," Cohen responded.Cohen was sentenced to three years in prison Wednesday after pleading guilty to campaign finance violations, tax evasion, making a false statement to a bank, and making false statements to Congress.He had pleaded guilty in August in a Manhattan US attorney's case to two campaign-finance violations tied to payments he made or orchestrated to adult-film star Stormy Daniels and former Playboy model Karen McDougal to stay silent about alleged sexual encounters with Trump.Prosecutors have said that in executing the payments, Cohen "acted in coordination with and at the direction of" Trump, who has denied having the affairs with the two women.Cohen said Trump is a very different person than the man he used to work for."I think the pressure of the job is much more than what he thought it was going to be," Cohen said. "It's not like the Trump Organization where he would bark out orders, and people would blindly follow what he wanted done. There's a system here -- he doesn't understand the system." 2821

President Donald Trump’s push to reopen schools is being complicated by a split within his ranks over how to do it. Some advisers are advocating for a massive federal expenditure to make campuses safe. This comes Congress is compiling the next COVID-19 relief bill. Senate Majority Leader Mitch McConnell said Monday schooling will be a priority in the coming package. Senate Democrats have proposed a 0 billion education stabilization plan. But the Republican leader has not said how much Congress is willing to spend. He's wary of high-dollar spending that will run into resistance from GOP senators. Vice President Mike Pence assured governors on a private call that talks are underway for “additional” education funds from Congress, and he repeated that at a higher education event in Louisiana Tuesday afternoon. 828
President Donald Trump was asked on Wednesday if he would commit to leaving office peacefully in January if he loses to Joe Biden in November.Trump’s response:“We're going to have to see what happens, you know I have been complaining very strongly about the ballots. And the ballots are a disaster,” Trump said.When pressed to elaborate, Trump added, "We want to get rid of the ballots, we'll have a very peaceful -- there won't be a transfer, frankly, there will be a continuation."Last week, Joe Biden said during a CNN town hall that he would accept the outcome once the full results are counted.“I mean, he never think -- can anybody any of you or history majors out there think of any president who said early on, ‘I'm not sure I'm going to accept the results of the election. It depends,’” Biden said. “I mean what's happened to us in this case, it's not who we are. This is not what America is. No presidents ever said anything like that.Trump has expressed doubt in mail-in voting during the 2020 election cycle, claiming that mail-in voting is prone to fraud. But many states, some of which are led by Republicans, are ramping up mail-in voting efforts. Proponents of mail-in voting say that it is a safer alternative than in-person voting given the coronavirus pandemic.Meanwhile earlier this month, US Attorney General William Barr said that voting by mail is “playing with fire.”“We're a very closely divided country here,” Barr told CNN’s Wolf Blitzer. “And if people have to have confidence in the results of the election and the legitimacy of the government and people trying to change the rules to this, to this methodology, which as a matter of logic is very open to fraud and coercion, is reckless and dangerous. And the people are playing with fire."While there is scant evidence of widespread voting fraud in past elections, there are questions on the US Postal Service’s ability to return ballots in time to be tabulated.In Florida, Volusia County Elections said more than 1,000 ballots that should have been counted for last month’s primary did not arrive on time. There were 1,281 ballots postmarked the day before Election Day, but election officials received them too late to be counted.Yesterday, the FBI issued a warning that cybercriminals and foreign governments were working to sow distrust in the upcoming election process.According to the FBI, “Foreign actors and cybercriminals could create new websites, change existing websites, and create or share corresponding social media content to spread false information in an attempt to discredit the electoral process and undermine confidence in U.S. democratic institutions.”Beyond attempts to influence the vote, the FBI says these actors are attempting to sow distrust in the electoral system. The FBI in particular warns that cybercriminals could take advantage of the likelihood several states will need additional time to count ballots due to increased mail-in voting and social distancing protocols. While a delay in results does not indicate any wrongdoing, the FBI warns that foreign actors could attempt to spread misinformation to cause distrust in the system while votes are being tallied. 3187
PUNTA GORDA, Fla. -- A Charlotte County deputy was forced to use his firearm to defend himself from charging dogs during a call Thursday morning.According to the Charlotte County Sheriff's Office, the deputy responded to a call from a resident who was afraid to exit his truck due to three loose and aggressive pit bulls in his yard.The deputy arrived to observe the dogs, described as approximately 100 pounds each, leaving the man's yard and chasing chickens in the next yard.As the deputy was speaking to the resident, the dogs returned and began to charge the men, forcing the resident back into his truck and chasing the deputy around it.The deputy fired his weapon at two of the dogs before they retreated down the road.Animal Control arrived and took the dogs into custody, giving the injured dogs treatment.They are investigating any possible citations for the owners. 889
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