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For the first time in more than a decade, a new treatment to improve brain function for Alzheimer’s disease has been submitted to the Food and Drug Administration (FDA) for review.This was after the drug trial was stopped and then a second look revealed some promising results.The Waterhouse family has seen the impact of Alzheimer’s firsthand.Gina and Steve Waterhouse have been a team most of their lives. They’ve been married for 43 years and ran several businesses together. Then in 2016, things started to change. Gina didn’t notice anything but employees at the family's businesses did.“I wasn't remembering some of the stuff I was supposed to be doing,” said Gina.Gina was diagnosed with early Alzheimer's disease that year.“They said, 'well you can come back in a year. We will check and see how you're doing, or we have a drug trial if you're interested,'” said Gina.Gina and Steve spent the next two and a half years at the Mayo Clinic, where Gina eventually got high doses of the drug aducanumab.Steve started to notice Gina was remembering more things and reported it back to doctors.“He just smiled and said, 'let me tell you what we're seeing. We're seeing cognitive improvement. And it’s the first time in my career.' These doctors said in their career that we've ever seen it,” said Steve.“He was so excited,” said Gina.Then in 2019, the drug trial suddenly ended. Gina says she felt like she’s gone downhill a little since it did.Rebecca Edelmeyer, PhD, with the Alzheimer’s Association, says the trial stopped early based on a futility analysis.“It was a statistical analysis that was done by the Biogen team, predicting that the trial would not actually be successful,” said Edelmeyer.Edelmeyer says then upon a second look at the trial data, they found that those people on the highest dose of the drug were seeing improvement in their brain function. She called it a very important moment for the Alzheimer’s research community.Now, the government will determine whether or not the drug is safe and effective enough to use.Steve mentioned there were some possible side effects like bleeding of the brain, but Gina did not experience any.Meanwhile, Gina can no longer take the drug. She and Steve have decided to retire.“We just decided tomorrow has to come today and we're having a great time. We're loving life,” said Gina.You can learn more about aducanumab here. 2394
First lady Melania Trump's spokeswoman went after rapper T.I. Tuesday, whose most recent music video features a Trump lookalike dancing without clothes in a fake Oval Office."Like it or not, she is the first lady and this is the White House," Stephanie Grisham, Trump's communications director, told CNN in a statement. "It's disrespectful and disgusting to portray her this way simply because of politics. These kinds of vulgar attacks only further the divisiveness and bias in our country -- it needs to stop." 520
FRANKLIN TOWNSHIP, Ohio (WCPO) -- A firefighter in Franklin Township, Ohio who posted a racial slur on his Facebook page saying he'd save a dog over a black person has resigned, according to The Journal-News.Tyler Roysdon submitted his resignation late Monday night, township officials told the newspaper, after his racially charged comment got him suspended on Sept. 12.Roysdon’s since-deleted Facebook post has made national news. He purportedly stated that, given the choice, he would save a dog before a black person -- posting “one dog is worth a million” and then using the N-word.Before his resignation, Middletown NAACP chapter president Dora Bronston called for Roysdon to be fired, saying a firefighter's job is "to be there for every person that calls on your help.""This person is 20 years old - apparently not mature enough to be a firefighter," Bronston said. "We trust those people with our lives to protect us, to keep us safe our families safe, and we don't want them to put us in harm's way."Without authority to fire Roysdon, Township Fire Chief Steve Bishop had placed Roysdon on indefinite suspension pending a disciplinary hearing. Township trustees had scheduled a disciplinary hearing for Roysdon for Sept. 27. 1297
Former NFL running back Kareem Hunt was accused of kicking a man at a nightclub in Kansas City, Missouri, in January 2018.The incident is the latest to come to light allegedly involving Hunt since video surfaced Friday showing him physically assaulting a woman in February. Three incidents of violence involving Hunt have been documented this year.No charges were filed in any of the cases. The Kansas City Chiefs released Hunt on Friday after TMZ posted the video. Hunt asked for forgiveness Sunday in an ESPN interview and admitted to lying to the Chiefs about the incident."I'm asking for forgiveness and I definitely believe I deserve forgiveness," Hunt told ESPN. "Everything is really happening fast right now, and I just want everybody to forgive me."Here is what we know about three incidents in which Hunt's name came up in 2018. 846
FILE - Dean Dillon accepts the Icon Award at the BMI Country Awards in Nashville, Tenn. on Nov. 5, 2013. Dillon, along with Hank Williams, Jr., and Marty Stuart, will be inducted into the Country Music Hall of Fame. (AP Photo/Mark Humphrey) 250