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A standoff between police and an armed suspect that resulted in one officer's death and the wounding of another remains underway Saturday afternoon in Pomona, California, near Los Angeles, more than 15 hours after it began.The suspect is barricaded inside an apartment home after fatally shooting an officer and wounding a second one, according to the Los Angeles County Sheriff's Department."It is with a heavy heart that I must report that one officer did not survive," Pomona police Chief Michael Olivieri tweeted early Saturday morning. "The second officer is in stable condition."  599

A stampede of Central American migrants rushed to the tracks Saturday when the first whistle of the train rang out.After a few days in Mexico City, it was time to continue their journey north to the US border. About 500 migrants traveling in a caravan climbed onto the freight train just outside the Mexican city of Tultitlán. 334

A team at the University of Kentucky is researching a possible treatment for COVID-19 and key helpers are three alpacas; Big Boy, Blue Eyes and Emperor.“It’s a powerful technology that we have at UK (University of Kentucky) and it’s something that hopefully we can develop some therapeutics with,” said Wally Whiteheart, a professor in the Department of Molecular & Cellular Biochemistry.Alpacas, along with llamas and camels, make a special kind of antibody called a nanobody. Nanobodies can be useful in cancer research and for other diseases. Researchers, led by Whiteheart and fellow professor Lou Hersh, are working with a nearby ranch to see what impact alpacas could have on COVID-19.“We, in a sense vaccinate them, and this case with viral proteins, and we make nanobodies to those viral proteins,” explained Whiteheart. “We can then go and purify and identify the nanobodies that bind to the virus and then test them to see if they can inhibit viral infection.”Making the nanobodies is just the first step. The team will see which, if any, can block virus infection and those candidates could move on to clinical trials.There’s still a lot of research and testing to go, and also still a lot of hope.“The cool thing which we’re exploring now is the fact that you might be able to use them as a nasal spray and this actually gets them to the place where the virus is affecting lung tissue,” said Whiteheart.This isn’t the first time the trio of alpacas has helped medical research. Big Boy, Blue Eyes and Emperor have contributed to the university’s nanobody research for more than three years. In that time, they have helped researchers generate more than 50 nanobodies to target proteins involved in a variety of human diseases including cancer, diabetes and neurological disorders.This story was originally reported by Alex Valverde on LEX18.com. 1869

A train carrying dozens of Republican members of Congress, including House Speaker Paul Ryan, to their legislative retreat in West Virginia hit a truck on January 31, 2017 leaving one person dead.Wednesday the National Transportation Safety Board released a preliminary investigation into the crash.They said around 11:15 a.m., a 2018 Freightliner truck equipped with a McNeilus Truck & Manufacturing refuse body was traveling southbound on Lanetown Road in Albemarle County near Crozet, Virginia.The refuse truck, operated by Time Disposal LLC, had a 30-year-old driver and two passengers as it drove towards a highway–railroad grade crossing, later identified. The crossing is active and includes advance warning signs and pavement markings on its approach, the National Transportation Safety Board said. The crossing is also equipped with crossbuck signs, warning lights, bells and gates.As the truck neared the highway a westbound Congressional Special Amtrak train was approaching the highway–railroad grade crossing.The NTSB said the train’s lead locomotive was equipped with a forward-facing track image camera. Data that was taken from the camera showed that as the crossing came into view, the gates were down and the truck was on the grade crossing. Witnesses to the crash reported that the refuse truck entered the crossing after the gates were down.The train’s recorder showed the Amtrak train was traveling about 61 mph when the engineer applied emergency braking. The train struck the left rear of the refuse truck, causing the truck to rotate counterclockwise and then collide with a railroad signal next to the tracks. The refuse body separated from the truck, and the truck’s two passengers were ejected, according to the NTSB.As a result of the crash, one passenger in the truck died. The other truck passenger had serious injuries and the driver of the truck had minor injuries. Three Amtrak crewmembers and three train passengers sustained minor injuries, the NTSB said.NTSB investigators and Albemarle County Police Department officials and the Federal Bureau of Investigation documented the crash scene and the characteristics of the crossing, the train and the refuse truck. The track and operational characteristics of the crossing signals were also examined and documented.The crash remains under investigation.  2354

A small town in Canada's Saskatchewan province mourned Saturday after a bus carrying a junior hockey team collided with a tractor-trailer, leaving 15 people dead and at least 14 injured."This is a dark moment for our city, our community, our province," Humboldt Mayor Rob Muench said Saturday afternoon at a news conference. "There is no playbook on what to do in cases like this."Members of the Humboldt Broncos hockey team were headed to the town of Nipawin for a playoff game Friday night when the crash happened north of Tisdale, the Royal Canadian Mounted Police said. 581