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The troubles facing Toys R Us aren't just about competition from Amazon and Walmart. A lackluster summer at the box office might be hurting the entire toy industry, which depends on hit movies to drive sales of licensed toys. 230
The researchers analyzed 139 bacterial samples from two Melbourne hospitals collected over 19 years ending in 2015. They studied how well each sample survived when exposed to diluted isopropyl alcohol.The isolates gathered after 2009 were, on average, more tolerant to the alcohol compared with bacteria taken from before 2004, the researchers discovered. Conducting mice experiments and further analysis, they also saw that alcohol-tolerant bacterial samples harbored several genetic mutations involved in metabolism, which made them better equipped to live in the gut.Although the results suggest that microbes can adapt to alcohols and other ingredients found in disinfectants, this conclusion cannot be drawn until more research is done, the researchers warn."There are two things we are working on," said Tim Stinear, a co-author of the study and professor at the University of Melbourne. "One is understanding exactly how the bacteria are becoming more tolerant. ... The second is what's going on in other parts of the world, and we are working with colleagues around the world to address that."One-third of all enterococcal infections in Australian hospitals are caused by E. faecium, according to Stinear and his co-authors. Of these, 90% were ampicillin-resistant strains, and half of those were resistant to vancomycin, another common antibiotic. Even when doctors try a higher-grade antibiotic to treat such illnesses, the outcome may be further drug resistance -- and a longer-lasting infection for the patient.Study co-author Paul Johnson, an infectious diseases professor and director of research at Austin Health in Melbourne, said that when it comes to preventing certain outbreaks, including vancomycin-resistant enterococci, hospitals might need to use more than standard precautions such as hand hygiene."We might need to specifically add additional control measures," he said. Such measures could include using an additional bacteria-killing agent, such as chlorhexidine, to sanitize hands in some medical care settings.True perhaps in hospitals, but the same might not apply to the world at large. 2118

The worry on Team Trump is negative headlines coming at a time that is already pressure-packed. Democrats could capture the House. A wave of administration personnel turnover is about to unfold. And there are year-end pressures as Congress returns with big post-election spending issues and the President heads overseas.Just the name "Mueller" makes the President angry, a Trump insider said in a weekend exchange. If the election goes poorly for the White House, this source suggested the President will be on edge, anyway. And if the investigations then roar back into the news, "I'm worried about a volcano." 611
The train had been inoperable due to weather conditions and downed trees, McMahan told CNN in an email. "UP crews worked overnight to clear the tracks."Passenger Emilie Wyrick told CNN the train moved about a half-mile Tuesday morning before stopping again.And Amtrak said it expects more delays as the formerly Los Angeles-bound train heads back north.Record-setting snowfallWhile they were stalled all those hours, passengers could see nearby Oregon Highway 58, closed due to snow and ice. The town of Oakridge has no electricity due to the weather, passenger Rebekah Dodson said.The National Weather Service had predicted Sunday that up to 2 feet could fall in the area. By Tuesday morning, at least a foot had accumulated, the weather service said. Oakridge averages 1.1 inches in February.Eugene, home to the University of Oregon about 45 miles northwest, had a record-setting 9.5 inches Monday, the weather service said.Amtrak spokesman Marc Magliari told CNN that none of the 183 passengers and dozen crew members were injured, but that after the accident "conditions further deteriorated with numerous track blockages from snow and fallen trees.""Due to worsening conditions, area road closures and no viable way to safely transport passengers or crews via alternate transportation, Train 11 stopped in Oakridge, Oregon," he said. "We are actively working with Union Pacific to clear the right of way and get passengers off the train."The train had power and enough food on board, for which passengers will not be charged, Amtrak said on Twitter on Monday.'A giant kumbaya party'With the help of heat, power and (so far) food, passengers said the mood on board has been surprisingly upbeat."It's just been like a giant kumbaya party," Dodson told CNN early Tuesday. "Strangers are playing cards. A teenager played his ukulele to kids to get them to sleep. Ladies who have never met before were dancing in aisles."Still, she said, the "hardship" has been stressful as passengers cannot go anywhere. The train is surrounded by feet of snow. Some Los Angeles-bound college students have "panicked" because their professors won't accept their excuse for missing class, Dodson said.Dodson said Tuesday morning that passengers had been told breakfast would be the last meal available.Dodson was trying to return home to Klamath Falls after a teaching conference in Portland.She said the passengers include families with children and a few dozen college students -- including about 20 students from Japan. Crew members had been "professional and nice" throughout.Passenger Carly Bigby told CNN affiliate 2605
The recommended sentence for the Solana Beach resident is nine months of prison time, a year of supervised release, a ,000 fine and restitution. 147
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