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WASHINGTON, Oct. 3 (Xinhua) -- Researchers at St. Michael's Hospital in Canada have discovered a new function for an enzyme that may protect against organ injury and death from anemia, according to a study appearing Monday in the U.S. journal of the Proceeding of the National Academy of Sciences.Researchers found that when people have anemia, neuronal nitric oxide synthase (nNOS) -- an enzyme in nerve cells that produces nitric oxide, an important signaling molecule in the body -- increases the body's ability to respond, adapt to low oxygen levels and makes the body more efficient in delivering oxygen to tissues. They also found that levels of nNOS in the brain increased in anemic mice, and that the mice without this enzyme die earlier, and with higher hemoglobin levels."Identifying this mechanism may lead to new therapies and approaches to improving outcomes for anemic patients," said Dr. Greg Hare, a researcher at the Li Ka Shing Knowledge Institute of the hospital and one of the lead investigators of the study.Anemia occurs when blood has a lower than normal number of red blood cells or hemoglobin -- an iron-rich protein that carries oxygen from the lungs and heart to the rest of the body. Cells need oxygen to survive and to produce energy for all bodily functions. The condition has many different causes including infection (malaria, HIV, parasites), nutritional deficiencies (iron, folate, B12), genetic mutations, pregnancy, trauma and surgical blood loss."This research will help us identify when an anemic patient is at greatest risk for injury and death when undergoing surgery," said Hare. "Research is underway to test these findings in humans."
BEIJING, Nov. 11 (Xinhua) -- Senior leader Zhou Yongkang on Friday urged Chinese judiciary and police officers to "creatively" handle cases in a bid to achieve a balance between law enforcement and social sensitivity.Zhou, secretary of the Communist Party of China Central Commission for Political and Legislative Affairs, made the remarks at a meeting with Zhan Hongli, a veteran female judge of a juvenile court in southern Fujian province.Zhou urged judiciary workers and police to learn from Zhan, who has not received a single complaint of misjudging in nearly 500 criminal cases involving 1,140 juveniles.In her 27 years of work in courts, she cared for the juveniles like a mother and creatively worked out a feasible judgment method for handling cases of young offenders, said Zhou, who is also a member of the Standing Committee of the Political Bureau of the CPC Central Committee.Zhan addressed saving the juveniles with education and persuasion as well as helping them go back to school and reintegrate into society, an approach which had positive benefits and won favorable comments from the young offenders' families and the public, Zhou said.Zhou also urged judiciary and police officers to enhance the quality of law enforcement and case handling by adhering to principles of fairness and transparency, so as to better settle conflicts among the people.
BEIJING, Nov. 5 (Xinhua) -- China's top political advisor Jia Qinglin's official goodwill visit to Greece, the Netherlands and Germany has deepened the friendship, promoted cooperation and enhanced understanding between China and the three nations, a Chinese official says.The visit was important in further deepening the friendship and mutual trust, promoting pragmatic cooperation and pushing forward the healthy development of relations between China and Europe, said Wang Shenghong, vice secretary general of the National Committee of the Chinese People's Political Consultative Conference (CPPCC).Jia, chairman of the CPPCC National Committee, had in-depth exchanges of views and reached broad consensus with government and parliament leaders of the three countries on issues related to bilateral ties and international and regional issues of common interest, said Wang, who accompanied Jia on the tour from Oct. 23 to Nov. 4.Jia Qinglin (R), chairman of the National Committee of the Chinese People's Political Consultative Conference, meets with Greek President Karolos Papoulias in Athens, Greece, on Oct. 24, 2011.During his visits, Jia also witnessed the signing of 15 inter-governmental agreements and commercial contracts, had extensive contact with people from different walks of life and visited some big-name companies.STRENGTHEN POLITICAL MUTUAL TRUST AND BUILD UP BILATERAL TIESDuring meetings and talks with leaders of the three countries, Jia expressed China's readiness to maintain the high-level exchanges of visits, build up political mutual trust, advance pragmatic cooperation, promote people-to-people and cultural exchanges and strengthen coordination in international affairs, Wang said.Jia said China is ready to work with the three nations to further advance bilateral ties and China-European Union (EU) relations.Greece's government and parliament leaders thanked China for its precious support at a time when Greece is being badly hurt by the financial crisis. Dutch leaders expressed their willingness to strengthen dialogue and cooperation with China in their joint response to the Europe debt crisis and other challenges. And German leaders praised China's positive role in overcoming the effects of the international financial crisis and stabilizing the world economy, Wang said.
WASHINGTON, Nov. 18 (Xinhua) -- The U.S. Food and Drug Administration (FDA) on Friday approved Erwinaze to treat patients with acute lymphoblastic leukemia (ALL), who have developed an allergy to E. coli derived asparaginase and pegapargase chemotherapy drugs used to treat ALL.Acute lymphoblastic leukemia is a type of cancer in which the bone marrow makes too many lymphocytes, a type of white blood cell. White blood cells help the body fight infection and are formed in the bone marrow.Erwinaze is injected directly into the muscle three times a week and works by breaking down one of the body's protein building blocks (the amino acid, asparagine) that is present in the blood, and is necessary for the growth of all cells. Leukemia cells cannot produce this protein building block. When a patient is treated with Erwinaze the leukemia cells die. Normal human cells are able to make enough asparagine for their own needs through biosynthesis and will not be affected by treatment with Erwinaze."The approval of Erwinaze underscores the FDA's commitment to the approval of drugs for conditions with limited patient populations with unmet medical needs using novel trial endpoints," said Richard Pazdur, director of the Office of Hematology and Oncology Products in the FDA's Center for Drug Evaluation and Research.Side effects associated with Erwinaze treatment include serious allergic reactions, inflammation of the pancreas, high blood levels of liver enzymes, blood clotting, bleeding, nausea, vomiting and high blood sugar.
BEIJING, Jan. 14 (Xinhua) -- A Spring Festival gala was held at the Great Hall of the People Saturday to entertain the country's military officers, soldiers and civilians.Representatives of officers and soldiers in the military units and armed police forces in Beijing as well as some Beijing residents attended the gala.President Hu Jintao and other top Chinese leaders including Wu Bangguo, Jia Qinglin, Li Changchun, Xi Jinping, Li Keqiang, He Guoqiang and Zhou Yongkang were also present at the gala.Hu expressed greetings to the audience and extended his good wishes for them, ahead of the traditional Spring Festival, or the Chinese Lunar New Year, which falls on Jan. 23 this year.