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SAN DIEGO (KGTV) — The National Institutes of Health highlighted research Tuesday out of UC San Diego that could unlock a new way to treat COVID-19.The research reveals new insight into how the coronavirus hijacks cells, and how doctors might be able to set traps or decoys to combat the virus. The findings were published in the journal Cell last month.“It does open up another avenue for a potential treatment,” said UC San Diego distinguished professor Dr. Jeffrey Esko. “It’s not a cure. It would be something that would tamp down infection potentially.”Since January, scientists around the world have understood that SARS-Co-V2, the official name of the new coronavirus, enters cells by latching onto a specific receptor on the cell’s surface, called ACE2.The UCSD team, led by Dr. Esko and visiting scholar Dr. Thomas Clausen, discovered that this entry mechanism is actually a two-step process, and the virus must also attach to a long chain of sugars called heparan sulfate.“We’ve shown this is fundamental to the infectious mechanism, so it needs to be part of every study from now on,” said Clausen.All cells are coated with a complex layer of sugars, or carbohydrates, called glycans. Heparan sulfate is one type of glycan that is known to play a key role in the infection process in several viruses, including herpes and other coronaviruses.It’s a complicated process to picture so the researchers offer an analogy: imagine a bird, soaring over trees, hunting a worm on the forest floor. The bird is the coronavirus and the trees are the thick layer of glycans that coat the surface of the cell.To reach the worm, which in this case is the receptor ACE2, the bird must navigate its way through the trees, specifically through heparan sulfate.The UCSD found that by removing the heparan sulfate trees with an enzyme, they were able to prevent the virus from infecting cells. In laboratory testing, they also found a second technique worked to foil the virus: introducing more trees as bait.The team found that heparin, an FDA-approved drug that is similar in structure to heparan sulfate, successfully acted as decoy. Heparin is a widely used drug designed to treat blood clots. Since blood clots and strokes are common complications with COVID-19, many doctors already administer heparin to patients.The UCSD team demonstrated that the two approaches can block infection in lab-grown cells about 80 to 90 percent of the time.“Certainly in the laboratory you can demonstrate that it works, but to deploy it and use it as a therapeutic has not been demonstrated,” Esko said.The NIH noted that more studies are planned to explore whether heparin, heparan sulfate, or drugs that target heparan sulfate might yield a viable COVID-19 treatment.Dr. Esko said he’s already been in talks with companies that plan to use their study as a rationale for a clinical trial.“It is very humbling when you realize we’re working on a pandemic right now, and maybe what we’ve done can contribute to a treatment for the disease,” he said. 3038

SAN DIEGO (KGTV) -- The National Weather Service is warning beachgoers ahead of the July 4 holiday about elevated surf and strong rip currents. A beach hazards statement will remain in effect until Friday at 3 a.m. According to the National Weather Service, waves will reach three to six feet accompanied by dangerous rip currents. “Remember to swim near a lifeguard if going out in the ocean,” said 10News meteorologist Megan Parry. RELATED: Check your Fourth of July forecastTidal overflow is also possible is areas prone to flooding, such as low-lying areas. “Tidal overflow will be possible in low lying areas during high tide between 9pm and midnight each night - keep that in mind when setting up to watch any fireworks shows during the day as the high tide moves in it may push you back by the night,” Parry added. Swells are expected to build again Friday through Sunday from Hurricane Barbara. 911

SAN DIEGO (KGTV) - Summer vacation. A time for kids to cut loose and enjoy weeks of freedom. And as studies have shown, to forget chunks of what they learned the year before. Even shorter breaks can erase some lessons.A special program at San Diego Unified is helping keep kids stay sharp and excited about learning all year round, even during breaks. It's about making learning a fun, family affair.In a classroom at Rosa Parks Elementary School in City Heights, 7-year-old students Melody and Isabella are getting some one-on-one attention with their lessons. The teachers in this case are Melody's grandmother and Isabella's mom."Everyday they have to read. Everyday they have homework to do," said Anna Gonzalez. She and Maria Theresa Jaume are among a growing number of parents and guardians getting more involved with their kid's education through the "Family Engagement Department" at San Diego Unified."So, I now know how to ask her questions," says Gonzalez, "How to engage her with the reading and things like that.""It solidifies the bond right," says Family Engagement Program manager Pamela King, "It shows kids that education is important." King says the program was established in 2016, inviting families to become partners in their kid's education with tips on how to do it."You're reading a fiction book. You're learning about the characters but what are characters thinking? What's motivating the character? So, going a little deeper."Organizers say it's about connecting with a child's curious nature. Making reading as fun as playtime, or as close as possible.You can find out more about the family engagement program here. 1651

SAN DIEGO (KGTV) - Tempers flared at a meeting of the Community Review Board On Police Practices Tuesday night. Dozens spoke out against the San Diego Police Department’s chokehold policy. Members of the Racial Justice Coalition wants to ban the practice, saying it’s excessive force and potentially deadly.  San Diego’s new police Chief David Nisleit called the comments at the meeting “passionate.” He said he heard them loud and clear but had questions about the doing away with the chokehold as some law enforcement agencies around the country have done.“Anytime you take a use of force tactic away from an officer, they generally have to go a higher level,” Nisleit said. “So my concern on that, and why I’m hitting pause to take a hard look at this, is I want to make sure that if we continue or discontinue, it's for the very right reasons. I want to look at the LAPD and the Chicago Police Department and their information on what has happened prior to and more importantly, what has happened afterward to see if more higher level of force had to be used.”The chokehold is expected to come to the review board again at their May meeting. 1163

SAN DIEGO (KGTV) — The "Capital of Craft" made its name known at the Great American Beer Festival in Colorado this weekend.San Diego breweries took home 17 medals from the massive festival, which features blind-taste testing of nearly 9,500 beers from almost 2,300 breweries. Since the first festival in 1982, San Diego breweries have grabbed 233 medals.At this year's event, local breweries claimed eight gold, four silver, and five bronze medals at the annual brew competition. Here's where you can try the award-winning ales:GoldAleSmith Brewing Co.: Private Stock Ale (Old Ale or Strong Ale)Breakwater Brewing Co.: Rye Dawn (Rye Beer)Pizza Port – Bressi Ranch: Chronic Amber Ale (Ordinary or Special Bitter)Pizza Port – Solana Beach: SeaSide Stout (Classic Irish-Style Dry Stout)Second Chance Beer Co.: Tabula Rasa (Robust Porter)SouthNorte Beer Co.: Sea Se?or! Mex Lager (American-Style Cream Ale)The Lost Abbey: A Creator’s Calling (Aged Beer)Two Roots Brewing Co.: Enough Said N/A (Non-Alcoholic or Alcohol Free Beer)SilverCoronado Brewing Co.: Freebooter Barleywine (Barley Wine-Style Ale)SouthNorte Beer Co.: Agavemente (Specialty Beer)Stone Brewing World Bistro & Gardens – Liberty Station: Stone Liberty Station Cimmerian Portal (American-Style Stout)Thunderhawk Alements: Bowie Knife (American-Style Black Ale)Saint Archer Brewing Company: Citra Pilsner (Contemporary American Style Pilsner)BronzeChula Vista Brewery: Browner Than Ivan (American-Style Brown Ale)Coronado Brewing Co. – Production Facility: Weekend Vibes IPA (American-Style India Pale Ale)Kilowatt Brewing: OB Bubble Dubbel (Belgian-Style Dubbel)Resident Brewing Co.: Industrial Gris (Belgian- and French-Style Ale)Rip Current Brewing: Rescue Buoy Imperial Stout (Imperial Stout)"The San Diego Brewers Guild is extremely proud of San Diego’s consistently strong showing at GABF," said Kris Anacleto, Vice President of San Diego Brewers Guild. "“It is because of our craft beer community’s pioneering spirit and innovation that San Diego’s craft beer legacy continues to thrive in today’s hyper-competitive national landscape."The accolades help reaffirm San Diego's reputation for craft beer. In 2018, the local craft beer industry accounted for .2 billion in economic impact on the region.San Diegans will surely have the chance to enjoy some of the award-winning brews and more soon enough during San Diego Beer Week, taking place Nov. 1 - 10. 2437