吴忠高级婴儿头部静脉穿刺训练示教模型(江苏小儿综合穿刺术与叩诊检查技能训练模型) (今日更新中)

WASHINGTON, April 11 (Xinhua) -- In the first clinical trial of gene therapy for treatment of intractable pain, U.S. researchers from the University of Michigan's Department of Neurology observed that the treatment appears to be able to provide substantial pain relief.In a study published online in the Annals of Neurology and seen on Monday, the researchers showed that the novel agent NP2 is safe and well-tolerated. In addition, measures of pain in the treated patients suggested that NP2 may provide a substantial analgesic effect.NP2 is a gene transfer vector that expresses the naturally- occurring opioid peptide enkephalin. In preclinical work in animals, David Fink, chair of the Department of Neurology, and his coworkers had demonstrated that injection of NP2 into the skin reduces pain in models of pain caused by nerve damage, inflammation or cancer.In the clinical trial, 10 patients with unrelenting pain caused by cancer were injected with the gene transfer agent in the area of skin related to the location of pain."The concept underlying this therapeutic approach is that injection of NP2 into the skin results in uptake into the nervous system and the production and release of a pain-relieving chemical in a controlled site in the pain pathway," says Fink. "In the study, patients who received the low dose of vector showed little reduction in pain; patients receiving the higher doses showed a greater than 80 percent reduction in pain over the course of four weeks following treatment."Fink's laboratory has been working on the use of modified herpes simplex virus-based vectors that are taken up by sensory nerves following skin injection to develop therapies for diseases of the nervous system for more than 20 years. Patents related to this technology have been exclusively licensed by Diamyd Medical, a publicly-traded Swedish biotechnology company that sponsored the trial, and the human-grade vector NP2 was produced by Diamyd, Inc, the U.S. subsidiary of Diamyd Medical.A phase 2 trial to compare NP2 to a placebo control has already been initiated under sponsorship from Diamyd.

CAPE CANAVERAL, Florida, April 29, (Xinhua) -- NASA on Friday delayed space shuttle Endeavor's launch to no earlier than Monday afternoon due to technical problems with heaters in the shuttle's auxiliary power unit."Shuttle Endeavor's launch now no earlier than Monday at 2:33 p. m. EDT (1833 GMT)," NASA said. "Engineers need that time to troubleshoot an issue that resulted in today's launch scrub."During Friday's countdown, engineers detected a failure in one of two heater circuits associated with Auxiliary Power Unit (APU) 1. Heaters are required to keep the APUs' hydrazine from freezing on orbit.Space shuttle Endeavour sits on the launch pad at the Kennedy Space Center at Cape Canaveral, Florida,  April 28, 2011. The Endeavor is scheduled for a Friday afternoon launch.U.S. President Barack Obama, touring storm damage in Alabama on Friday, had been expected to attend the planned 3:47 p.m. (1947 GMT) launch. Obama will still visit Cape Canaveral and then travel to Miami, where he is scheduled to speak at a community college commencement.Endeavor's 14-day mission will deliver the Alpha Magnetic Spectrometer-2 (AMS) to the International Space Station. AMS, a particle physics detector, is designed to search for various types of unusual matter by measuring cosmic rays.Its experiments are designed to help researchers study the formation of the universe and search for evidence of dark matter, strange matter and antimatter. Endeavor also will fly the a platform that carries spare parts that will sustain space station operations once the shuttles are retired from service.The mission will feature four spacewalks to do maintenance work and install new components. These are the last scheduled spacewalks by shuttle crew members.Endeavor, which has been promised to the California Science Center in Los Angeles upon its return, was the replacement ship for Challenger, which was lost in a 1986 explosion as it ascended over the Atlantic that killed seven astronauts.It will be the second of NASA's three surviving shuttles to be retired. Sister ship Discovery, which will be transferred to the Smithsonian National Air and Space Museum, completed its last flight in March.Atlantis' final launch is scheduled for June 28. When the U.S. space shuttle program officially ends later this year, the Russian space program's Soyuz capsule will be the only method for transporting astronauts to and from the station.

LOS ANGELES, April 3 (Xinhua) -- People with lower levels of vitamin D are more likely to have stiffer arteries and an inability of blood vessels to relax, U.S. researchers have found.This finding also applies to people who are in general good health, according to researchers from the Emory University School of Medicine.The researchers presented their findings on Sunday at the annual American College of Cardiology meeting in New Orleans.Impaired vascular health in correlation with lower vitamin D levels contributes to high blood pressure and the risk of cardiovascular disease, the researchers say.The study involved 554 participants, with the average age of 47 and generally healthy.The average level of 25-hydroxyvitamin D (a stable form of the vitamin reflecting diet as well as production in the skin) in participants' blood was 31.8 nanograms per milliliter. In this group, 14 percent had 25-hydroxyvitamin D levels considered deficient, or less than 20 nanograms per milliliter, and 33 percent had levels considered insufficient, less than 30 nanograms per milliliter.The researchers monitored the ability of participants' blood vessels to relax by inflating and then removing a blood pressure cuff on their arms. To allow blood to flow back into the arm, blood vessels must relax and enlarge -- a change that can be measured by ultrasound. The researchers also made other measurements of smaller blood vessels and examined the resistance to blood flow imposed by the arteries.

BEIJING, Feb. 16 (Xinhua) -- China's police forces have formed a nationwide computerized network to share information about fugitives, fingerprints, stolen vehicles and other crimes.Sources with the Ministry of Public Security said Wednesday that almost all police officers throughout the country have access to the network, including those in border checkpoints and exit-entry administrations.The network can verify the identification cards of Chinese citizens and help the police with anti-terrorism and anti-drug operations, a statement released by the ministry said.The Public Security Ministry is working with other government agencies such as the ministries of national security and foreign affairs, the central bank and civil aviation administration to share information from the network.

WASHINGTON, April 19 (Xinhua) -- The U.S. National Aeronautics and Space Administration (NASA) on Tuesday set April 29 as the launch date for Endeavour's final voyage.The date was announced Tuesday at the conclusion of a flight readiness review at Kennedy Space Center. During the meeting, senior NASA and contractor managers assessed the risks associated with the mission and determined the shuttle and station's equipment, support systems and personnel are ready.Liftoff time is 3:47 p.m. EDT (1947 GMT). It will be the 134th shuttle mission overall, the 25th for Endeavour and the 36th shuttle mission to the International Space Station.Endeavour will deliver to the station a 2-billion-dollar, multinational particle detector known as the Alpha Magnetic Spectrometer.Space shuttle Endeavour sits on launch pad 39A with the crew aboard minutes before mission managers scrubbed the launch again at Cape Canaveral, Florida, July 13, 2009.The spectrometer, also designated AMS-02, is a particle physics experiment module that is to be mounted on the station. It is designed to search for various types of unusual matter by measuring cosmic rays. Its experiments will help researchers study the formation of the Universe and search for evidence of dark matter and antimatter.Endeavour's two-week mission was led by Commander Mark Kelly. Other crew include Pilot Greg Johnson, NASA Mission Specialists Michael Fincke, Andrew Feustel and Greg Chamitoff and European Space Agency Mission Specialist Roberto Vittori. Astronauts are planning to step out on four spacewalks to do maintenance work and install new components.NASA's 30-year-old shuttle program is ending this year due to high operating costs. The Obama administration wants to spur private companies to get into the space taxi business, freeing NASA to focus on deep space exploration and new technology development.Shuttle Atlantis is set for its final journey into space at the end of June. Its return to earth will mark the official end of the U.S. space shuttle program. After that, the Russian space program' s Soyuz capsule will be the only method for transporting astronauts to and from the station.

来源：资阳报