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The Tulsa Health Department will contact any individual or setting deemed at risk for exposure for all confirmed positive COVID-19 cases among Tulsa County residents. The virus spreads primarily through respiratory droplets among individuals within close personal contact (within 6’) for a prolonged period of time (ten minutes or longer). Anyone with concerns about their risk of exposure can contact the Tulsa Health Department at 918-582-9355.The Tulsa Health Department respects those exercising their right for peaceful assembly. Crowds and large gatherings can be a conduit for the transmission of COVID-19, which is spreading in our community. All residents are encouraged to exercise their right to gather and protest safely, which includes wearing a cloth face covering to protect those around you, use hand sanitizer when soap and water are not readily available, practice social distancing, and avoid touching your face. We want to encourage residents to use their voice, but do so safely.Today, we reported an additional 34 cases and three deaths in our community, bringing the cumulative total to 1,057 and 57 respectively. 1144
The U.S. regulators who will decide the fate of COVID-19 vaccines are taking an unusual step: Asking outside scientists if their standards are high enough.The Food and Drug Administration may have to decide by year’s end whether to allow use of the first vaccines against the virus. Thursday, a federal advisory committee pulls back the curtain on that decision process, debating whether the guidelines FDA has set for vaccine developers are rigorous enough.“We will not cut corners, and we will only use science and data to make that determination,” FDA Commissioner Stephen Hahn pledged at a meeting of the Milken Institute Wednesday.Exactly how much data his agency needs to be sure a vaccine is safe and effective is a key question for the advisers. An even bigger one: If the FDA allows emergency use of a vaccine before final testing is finished, will that destroy chances of ever learning just how well that shot -- and maybe competitors still being studied -- really work?“We can’t lose sight of the fact that it is in our societal interest to see these trials to completion,” said Dr. Luciana Borio, a former FDA acting chief scientist who will be watching the advisers’ debate.Plus, multiple vaccines are being studied -- shots made with different technologies that each have pros and cons.“The first vaccine is not necessarily the best vaccine,” cautioned Dr. M. Miles Braun, a former FDA scientist now with Georgetown University School of Medicine. If the trials aren’t allowed to finish, it may be difficult or impossible to ever know for sure.It’s a critical moment in FDA’s 114-year history. The government has spent billions to race a vaccine through a research process that usually takes years, and FDA faces unprecedented pressure from the Trump administration, fueling public skepticism that politics could overrule science.Interest is so high, FDA is airing the meeting on YouTube. Here are some key issues the committee will discuss:HOW MUCH EVIDENCE IS NEEDED?FDA is requiring manufacturers to do studies of at least 30,000 people to prove if a vaccine protects and how safe it is. Those studies must include adequate numbers of people at highest risk from COVID-19 -- older adults, minorities and anyone with underlying health problems.FDA has made clear that any vaccine must be at least 50% effective. And while the studies are designed to run for two years, companies may get enough evidence the shots are protective -- in at least some people -- to stop the trials early and seek what’s called an “emergency use authorization” for wider vaccinations.Despite White House objections, the FDA told vaccine makers earlier this month not to seek that speedier review until they’ve tracked at least half their trial participants for two months. With other vaccines, that’s about the amount of time when major side effects crop up.That’s not long enough, said the head of the non-profit ECRI Institute, which reviews medical technology for hospitals and insurers. In comments submitted to the advisory committee, ECRI’s Dr. Marcus Schabacker said FDA should require six months of follow-up.“Doing any less would simply risk too much, and the consequences may be severe,” he wrote. “A weak vaccine that loses public trust could poison the well for epidemic control for many years.”WOULD EMERGENCY USE DERAIL FULL ANSWERS ABOUT VACCINES?Normally when a study ends because of evidence that a vaccine is working, the participants who got dummy shots are offered the real thing.But if FDA allows emergency use of a COVID-19 vaccine, that’s not the same as having full proof the shot works, Borio cautioned.And if the participants in the placebo group are immediately offered the real shot, researchers may not be able to get answers about all the high-risk groups in the study — or tell how long the vaccine’s protection lasts, a process expected to take many more months.But Pfizer Inc., which with Germany’s BioNTech is developing one of the leading candidates, told FDA that if it’s granted emergency use authorization, it “would have an ethical obligation” to alert study participants who got a placebo and allow them vaccine access. The company wants FDA to look into “other scientifically and statistically sound methods” to determine long-term safety and effectiveness.Pfizer’s stance is likely to face pushback. The Infectious Diseases Society of America states that FDA’s panelists “should insist” that vaccine developers “present a compelling case” for how they will complete their trials if FDA grants early authorization of their vaccine.Clearing a vaccine based on premature or faulty data “could cause more harm” by “further eroding public confidence in all vaccines,” the group said.It’s an unprecedented dilemma. The FDA has previously allowed emergency use of only one vaccine, a decades-old shot that in 2005 was authorized to prevent anthrax poisoning.This time around, multiple COVID-19 vaccines are in the pipeline. Pfizer competitor Johnson & Johnson cautioned that early FDA clearance of one vaccine could “jeopardize integrity” of other ongoing trials if patients decide to drop out to seek the first cleared shot instead.The company asked regulators to explain what options are available to ensure completion of all ongoing COVID-19 vaccine trials.WHAT ABOUT LONG-TERM SAFETY MONITORING?Even a study of 30,000 people cannot spot a side effect that only strikes 1 in 100,000. So the government is planning extra scrutiny of every COVID-19 vaccine to hit the market.At first there will be limited doses given to just certain high-risk people -- and those early recipients are to get text messages daily for the first week after vaccination, and then weekly out to six weeks, asking how they’re feeling.FDA also will be checking databases of electronic health records and insurance claims, looking for any red flags.“There’s a kind of tracking that has to take place here on a massive basis that hasn’t taken place before,” said Dr. Jesse Goodman of Georgetown University, a former director of the FDA’s vaccine and biologics center.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 6274

The sky is lovely, dark and deep. But these golfers in Hawaii have rounds to go before they sleep.Stunning photos taken at Hawaii's Big Island on Tuesday show golfers coolly hitting the links even as a monstrous ash plume looms behind them.The eruption of the Kilauea volcano has already destroyed houses, caused evacuations and threatened to wreak havoc on Hawaii's tourism industry. On Tuesday, a plume of ash from the volcano rose 12,000 feet into the air, dropping ash on sections of the island.The US Geological Survey issued a red alert on Tuesday warning of an imminent major eruption.But clearly, not everyone was so worried. 646
The world is in the midst of a pandemic. While it's important to stay informed, and up-to-date on the latest COVID-19-related news, it's also OK to take mental breaks.Video games are among the best forms of entertainment to help provide an escape. Here are nine titles to help ease your stress.Animal Crossing: New Horizons(Nintendo Switch) KGUN's review 362
The Singapore Tourism Board is partnering with two cruise lines to provide cruises that won't visit any ports.The agency announced the pleasure cruises would operate at a 50% capacity, round-trip with no stops, and only open to Singapore residents."To provide assurance for safe cruising, the Singapore Tourism Board (STB) is developing a mandatory CruiseSafe certification program, which sets out stringent hygiene and safety measures throughout the passenger journey – from prior to boarding, to after disembarkation," the agency said in a press release.Before the ships can set sail, they must follow strict protocols to ensure everyone's safety, including passengers taking a mandatory COVID-19 test before boarding, providing 100% fresh air throughout the ship, and frequent cleaning.The Genting Cruise Lines' World Dream will begin sailing Nov. 6, and Royal Caribbean International's Quantum of the Seas will begin sailing in December, the agency said. 966
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