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SAN DIEGO (KGTV) -- Jury duty service in San Diego County resumed Friday after a lengthy stoppage caused by the coronavirus pandemic.Courtrooms across San Diego County shut down about seven months ago amid state-mandated restrictions. Now, jurors are able to report once again, with a slew of health and safety precautions in place.Because of the virus, courts have had to change the way they operate, and some lawyers believe this will also affect the process of picking a fair jury.Many aspects of the courts have changed, from added safety precautions to transitioning to virtual court.Prior to the pandemic, there were usually 350-400 people that are summoned to serve as jurors at the Central Courthouse in downtown San Diego. Now, that number has been reduced to 18%-20% of the usual capacity to allow for proper social distancing.Just as before, jurors do have the option to delay their service based on a number of factors including financial reasons, being a caretaker, or having a physical or mental condition.Defense attorney Jan Ronis told ABC 10News, “The kinds of options that were previously available now have new options, in respect to vulnerable conditions and age groups, things of that nature … it’s a whole new world.”Ronis said he believes COVID-19 concerns could impact the jury pool that’s available, with more people opting to postpone their service.“A jury of your peers, which represents a cross-section of society, racially, ethnic, gender-wise, diversify, as far as age and demographic, these are hugely important,” said Ronis.It’s just one of the main challenges the courts will have to deal with as they’re already facing a backlog of cases.Ronis added, “Everyone’s been in limbo; people need to get things resolved, criminal and civil litigants and family courts, things of that nature. It’s really created a horrific situation for so many people.”Jurors that have been called in to report will do so next Tuesday, which is when jury trials are scheduled to begin.Court officials say of the jurors that were summoned this week, nearly 40% have either postponed their service or have been excused from jury duty. 2151
SAN DIEGO (KGTV) — It's a disease that kills nearly a half million people a year. Mostly children. But painstaking work right here in San Diego is bringing the world ever closer to ending malaria."After you've been doing it for a while you get a little bit tired," said PhD student Madeline Luth, as she works over a microscope, "You're hands get a little bit shaky."She's part of a research team at UC San Diego involved in tedious, precise work."I'm using my syringe here to separate out a single mosquito," she said, "to isolate the thorax which contains all of the malaria parasites." Malaria is a parasite spread by mosquitoes; making the insect the deadliest organism on the planet -second only to humans. Millions of people -primarily in poor parts of the world like Africa- are made sick by the parasite every year. And hundreds of thousands die."What we're trying to do is interrupt the process so the infection never takes hold in your liver.," said Dr. Elizabeth Winzeler, who heads up the research team at the UC San Diego School of Medicine. "So you never develop any symptoms of the disease".Dr. Winzeler says here team has tested more than a half million compounds against the parasite. And is now about to release hundreds of promising mixtures to researchers around the world. "They can take the recipes and the information that we've used and start their own anti-malarial drug development," says Dr. Winzeler.The open door approach with no intellectual property protections, is made possible by billions of dollars in grants from the Bill & Melinda Gates Foundation. It is also a necessity since the vast majority of those new drugs will save, are too poor to pay for medicine. The venture is purely to save lives. "We're doing this for the good of humanity, says Dr. Winzeler, "And I think everyone is on board with this idea." Even if, says PhD student Madeline Luth, some of the work is hard to explain."It's a little strange telling people I dissect mosquitoes every Wednesday morning." 2022

SAN DIEGO (KGTV) - Just ahead of this holiday week, San Diego's Cross Border Xpress (CBX) unveiled new biometric facial comparison technology. The CEO of the sky bridge that connects travelers directly to the Tijuana International Airport told ABC 10News that it will further secure and streamline travel into the United States.The U.S.-Mexico border is still closed to non-essential travel because of COVID-19. CBX CEO Jorge Goytortua said CBX is still not encouraging people to travel right now but if they do, they can take advantage of this technology.“Within seconds, the technology will recognize the passenger in a [Customs and Border Protection (CBP)] database,” said Goytortua. He told ABC 10News that the comparison process happens only at a time and place where travelers are already required by law to verify their identity by presenting travel documents. Goytortua says that when a traveler arrives at the CBP processing area, he or she will have a photo taken at the primary inspection point. A CBP officer will do a review by retrieving the traveler's passport or visa photo from government holdings. The new photo will be compared to the previously collected photo.“It's going to be a hands-free process. It's going to be a much faster process,” he told ABC 10News.He added that CBX does not have access to the photos. Only CBP officers can see them. If travelers are still concerned about privacy, he said it's not mandatory to use the technology. “You can ask the officer if you don’t want to be processed like that then you will be processed the traditional way with your document read it on the scan. A CBP officer [will] research on their system and make sure that the person that is presenting the document is the one there in front of the officer,” he stated. 1790
SAN DIEGO (KGTV) — It’s a term we’ve heard a lot during the pandemic: emergency use authorization.From ventilators to diagnostic tests to experimental drugs like remdesivir, the Food and Drug Administration has issued at least 616 emergency use authorizations, or EUAs, since the pandemic began.“That’s such a powerful term: emergency use authorization,” said President Donald Trump on Aug. 23 when announcing an EUA for convalescent plasma.Top officials at the FDA are now floating the idea of using an EUA to speed up distribution of a vaccine against COVID-19, writing that it “may be appropriate” under certain circumstances. Critics contend it would be a dangerous move.The mechanism was put into law back in 2004, and EUAs have been used in several health emergencies since, including the 2009 H1N1 pandemic.An EUA allows the FDA to temporarily authorize a drug or device for use during an emergency under certain conditions. There must be no formally approved alternatives to the product, and the available evidence must suggest the potential benefits outweigh the potential risks.“Because in some emergencies, we just cannot wait for all the evidence needed for full FDA approval,” the agency says in a video explaining the rationale for an EUA.While EUAs are relatively common for diagnostic tests and experimental drugs, there has only been one EUA issued for a vaccine. In 2005, the FDA authorized a vaccine intended to protect U.S. soldiers from an anthrax chemical attack. It was the first time the FDA ever used the EUA process. In that case, the product, Anthrax Vaccine Absorbed, had been formally licensed in 1970 as safe and effective against anthrax on the skin, but was not formally approved to counteract inhaled anthrax.In a letter to pharmaceutical companies, the FDA said it “may be appropriate” to issue an EUA for a COVID-19 vaccine “once studies have demonstrated the safety and effectiveness” of the product, but before other steps in the traditional submission process, like detailed information on how the vaccine was made and tested.“It is extremely rigorous,” Dr. Christian Ramers of Family Health Centers of San Diego said of the typical FDA approval process. “People have to submit thousands of pages of documents. They have to open their books, essentially, and show all of the detail on how these things have been tested.”An EUA could allow for the release of a vaccine before the election, something President Trump has suggested but other members of his administration have said is unlikely.The prospect of an EUA for a vaccine alarms consumer advocates like Dr. Sidney Wolfe of Public Citizen, who sent a letter to the agency urging it to avoid the expedited process.“The amount of information on how effective it is, the amount of information on how safe it is is less than would be required for full approval,” Wolfe said. “And full approval could arguably come in three or four months.”Wolfe thinks an EUA could backfire.“The loss of confidence by people will contribute to a much decreased willingness to be vaccinated,” he said, citing a survey during the 2009 H1N1 pandemic that showed people were reluctant to volunteer for inoculation if the vaccine only had emergency authorization.Critics say there’s already shaky public confidence after reports of political pressure from the president in the EUAs for convalescent plasma and for hydroxychloroquine.In the latter case, the FDA revoked the EUA for the anti-malaria drug June 15 after more studies showed it wasn’t effective and could have serious side effects.Dr. Ramers at Family Health Centers of San Diego says there is a big ethical difference between authorizing an experimental drug with limited data and authorizing a vaccine.Fundamentally, doctors give drugs to patients who are already sick, and they're more willing to try something untested in a last-ditch effort. “In somebody who has been through two or three or four rounds of [chemotherapy] and nothing has worked, the risks and benefits are tilted in a different way,” he said.“But a vaccine is a really special situation because we’re giving it to healthy people. We’re giving it to the general population before they become ill. So historically, the safety threshold for a vaccine has been way, way, way higher,” Ramers added. 4302
SAN DIEGO (KGTV) - Like Pfizer, Moderna, AstraZeneca, and many others, INOVIO Pharmaceuticals has also raced to develop a COVID-19 vaccine this year.“We’ve been working really hard to move our vaccine through the stages of clinical testing. Some things have taken a little bit longer than we hoped. I think that’s kind of always the case when you’re trying to go at great light speed,” said Dr. Kate Broderick, INOVIO Pharmaceuticals Senior VP of Research & Development based in San Diego.Broderick said with funding from the U.S. Department of Defense, the biotech company started its Phase 2 clinical trial evaluating its DNA vaccine candidate, INO-4800.The first U.S. participants received a dose of the experimental vaccine earlier this month. Approximately 400 adults in the U.S. are expected to be enrolled in the trial by the end of the month.“We hope that in the early part of 2021, we’ll be going into a really large Phase 3 trial where we’re asking the question does our vaccine protect against the disease itself,” she said.Broderick said the company hopes to enroll about 6,000 participants initially in its Phase 3 trial once they get the green light to begin.A press release from the company last week stated that “The Phase 3 segment of the INNOVATE remains on partial clinical hold until INOVIO satisfactorily resolves the FDA’s remaining questions related to the CELLECTRA 2000 device that will be used to deliver INO-4800 into the cells of the skin.”Earlier data released from Pfizer and Moderna’s studies showing high vaccine efficacy was positive news for INOVIO.“We feel that we’re in a really good place. There’s eight billion people on the planet, and we’re certainly going to need quite a few different types of vaccines to ensure everybody is protected,” she said. “The Moderna and Pfizer vaccines are RNA vaccines; ours is DNA vaccine”Broderick said one significant benefit of INOVIO’S DNA vaccine candidate is it doesn’t have to be stored in low-temperature freezers, making it easier to ship out worldwide if approved.“In fact, we can keep it at room temperature, sitting on a desk somewhere for a year with no impact,” she said.INOVIO is projecting to have 100 million doses of its vaccine ready in 2021.“With these vaccines being approved, there is definitely an end in sight, but don’t let your guard down too fast,” she said. “Unfortunately, until everyone in the country gets vaccinated, we will still have to adhere to those kinds of annoying things, wearing masks, socially distancing. I know it’s frustrating, especially before the holidays, but just keep yourself safe and the people you love safe.” 2648
来源:资阳报