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BEIJING, Oct. 11 (Xinhuanet) -- An experimental drug that can remove amyloid plaques from the brains of Alzheimer's patients is being developed by Swiss Roche Holding AG in a small early-stage study, according to a report published in the Archives of Neurology on Monday.Researchers suspect the build-up of such plaques may be a cause of the memory robbing disease, although that theory has yet to be definitively proved. Gantenerumab, a biotech drug designed to bind to amyloid plaques in the brain and remove them, is being targeted at the early stages of Alzheimer's with the hope it can slow progression of the disease while patients are still able to function.The Phase I study of 16 Alzheimer's patients tested gantenerumab at two doses against a placebo over six months of treatment.The Roche drug led to a dose-dependent reduction of brain amyloid, while amyloid load increased in patients receiving a placebo, the report said.The next step will be to investigate whether removal of brain amyloid translates into clinical benefit for patients at doses of the experimental drug that are well tolerated and safe, the report said.Much larger trials and further study will be needed to fully understand how gantenerumab works and whether it can stave off Alzheimer's, said the report.Roche is approaching the disease far earlier because amyloid accumulates for 15 years before dementi.

WASHINGTON, Nov. 10 (Xinhua) -- The U.S. Food and Drug Administration (FDA) has sent warning letters to more than 1,200 retailers, the majority of which respond to violations relating to selling tobacco to minors, as part of its ongoing effort to reduce tobacco use among children, the agency announced Thursday in a statement.The FDA said that while most retail establishments have been found to be in compliance with the law, some retailers are still selling cigarettes and smokeless tobacco to minors. Warning letters may be followed by civil money penalties if retailers continue to violate the law."It should worry every parent that 20 percent of U.S. high school students smoke cigarettes," said FDA Commissioner Margaret Hamburg in a statement. "President Obama and the FDA are committed to preventing children from smoking. For many young people, that first cigarette or use of smokeless tobacco will lead to a lifetime of addiction, and for many, serious disease. More than 80 percent of adult smokers begin smoking before 18 years of age. Retailers are vital partners in the FDA's efforts to prevent tobacco use among kids."Obama signed the Family Smoking Prevention and Tobacco Control Act that gives the FDA authority to regulate tobacco products to prevent use by minors and reduce the impact on public health. One of the law's provisions permits the FDA to contract with states and territories to conduct compliance check inspections of tobacco retailers. In 2011, the FDA awarded compliance contracts totaling more than 24 million U.S. dollars to 38 states.The FDA also began inspecting U.S. tobacco product manufacturers in October 2011. This is the first time tobacco product manufacturing facilities have ever been inspected by a federal public health agency.

BEIJING, Dec. 27 (Xinhua) -- The People's Bank of China (PBOC), China's central bank, announced Tuesday that it is banning local regions, institutions or individuals from setting up gold exchanges apart from the existing Shanghai Gold Exchange and Shanghai Futures Exchange.The country also bans the establishment of any gold trading platforms in other exchanges, a statement on the PBOC website said.The statement said the country has ordered a cease to the building of any new gold exchanges or trading platforms. Those which have opened for business must cease operations.The ban came amid bigger risks in gold trading after some local regions, institutions and individuals grew enthusiastic in setting up gold exchanges and trading platforms in recent years as gold prices soared, which led to a surge of illegal practices due to inadequate management, the statement said.It added the central bank will work with the Shanghai Gold Exchange and Shanghai Futures Exchange to boost the healthy development of the country's gold trading market.

CANNES, France, Nov. 3 (Xinhua) -- Chinese President Hu Jintao met here Wednesday his French counterpart Nicolas Sarkozy on bilateral ties and other issues of common concern, including the Group of 20 summit scheduled for Thursday and Friday.Hu pointed out that since the global economic recovery is now burdened by quite a few instable and uncertain factors, the international community has great expectations of the G20 Summit in Cannes."The Chinese side actively supports the French side to host the summit," Hu said, emphasizing that the G20 should continue to uphold the spirit of cooperation and send a clear and definite signal of securing growth and promoting stability to the international community through this summit.Hu expressed the hope that all relevant parties should jointly endeavor to make the Cannes summit a conference of solidarity and win-win cooperation.Sarkozy expressed his appreciation of the effort China has made to prepare for the G20 summit. He said the French side was ready to strengthen coordination and cooperation with the Chinese side and work with all other parties to push for positive results at the summit.Hu said Europe is the largest economy in the world, and there will be no global economic recovery without a recovery of the European economy.He pointed out that the package deal that the European Union (EU) struck lately demonstrates its will and determination to resolve Europe's debt problem. He hoped that the implementation of the package deal would help overcome the difficulties facing Europe and be conducive to the recovery and growth of the European economy."It is mainly up to Europe to resolve the European debt problem," Hu said."We believe that Europe has all the wisdom and capability to resolve the debt problem," he added.Sarkozy said Europe is committed to resolving the debt crisis by making its own effort and strengthening cooperation with the international community. Hu said China wants to see Europe prosper.Noting that it was the third time for him to meet Sarkozy so far this year, Hu said the two sides had a frank and in-depth exchange of views on bilateral links, world economic situation, G20 affairs and major international issues and reached many important consensuses.The development of China-France relations has maintained good momentum recently. President Hu paid a state visit to France in November last year and met Sarkozy in March and August this year when the French president visited China.Hu said China places importance on developing its relations with France and the EU. He also thanked Sarkozy for France's meticulous preparation for the G20 summit and its hospitality to global leaders.France values China's role and appreciates its focus on major international issues, Sarkozy said, adding that his country is willing to maintain close communication and consultation with China.

WASHINGTON, Nov. 14 (Xinhua) -- Nearly a fifth of all Americans 12 years or older have hearing loss so severe that it may make communication difficult, according to a new study led by Johns Hopkins University researchers and published Monday in the Archives of Internal Medicine.The findings, thought to be the first nationally representative estimate of hearing loss, suggest that many more people than previously thought are affected by this condition.Study leader Frank Lin, an assistant professor, and his colleagues used data from the National Health and Nutritional Examination Surveys (NHANES), a research program that has periodically gathered health data from thousands of Americans since 1971. The researchers analyzed data from all participants age 12 and over whose hearing was tested during NHANES examinations from 2001 to 2008. Unlike previous estimates, NHANES includes men and women of all races and ages, from cities scattered across the country, so it's thought to statistically mimic the population of the Untied States.Using the World Health Organization's definition for hearing loss (not being able to hear sounds of 25 decibels or less in the speech frequencies), the researchers found that overall, about 30 million Americans, or 12.7 percent of the population, had hearing loss in both ears. That number jumps to about 48 million, or 20.3 percent, for people who have hearing loss in at least one ear. These numbers far surpass previous estimates of 21 to 29 million.Hearing loss prevalence nearly doubled with every age decade, with women and blacks being significantly less likely to have hearing loss at any age. Lin and his colleagues aren't sure why these groups appear to be protected. However, he notes that the female hormone estrogen, as well as the melanin pigment in darker skin, could have a protective effect on the inner ear.

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