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UPDATE (8:59:59 PM PT): The government shutdown is now in effect with no agreement reached.UPDATE (7:30 PM ET):A partial government shutdown will happen at midnight as the House of Representatives has adjourned for the evening.EARLIER STORY:With Washington just hours away from a partial government shutdown, lawmakers and President Donald Trump still have not yet reached a deal to stave off a shutdown.An effort to broker an agreement that would prevent a shuttering of key federal agencies appears to be underway, however. Republican Tennessee Republican Sen. Bob Corker said on the Senate floor late in the day Friday that an "understanding has been reached" that the Senate will not take any further votes related to the funding issue "until a global agreement has been reached between the President" and congressional leaders.It is not yet clear whether that effort will succeed in stopping a partial shutdown or exactly what it might involve.Corker made his remarks just after the Senate approved a motion to proceed to consideration of a House-passed spending bill that includes an additional billion for the President's border wall, and which has been widely considered dead on arrival in the upper chamber.Vice President Mike Pence, budget director Mick Mulvaney and Trump's son-in-law, Jared Kushner, were on Capitol Hill on Friday afternoon meeting with senators, including Senate Minority Leader Chuck Schumer, a New York Democrat, about finding a solution.RELATED: Government shutdown: Who will get furloughed if a spending bill is not signed?The President has repeatedly said he is unwilling to accept anything less than billion for his long-promised border wall. But the billion border wall bill's failure in the Senate shows the votes aren't there on the Hill to meet the President's demand.Funding for roughly a quarter of the federal government expires at midnight, including appropriations for the Department of Homeland Security, the Department of Justice, the Department of Housing and Urban Development and other parts of the government.Trump predicts shutdown after meeting with Republican senators Trump predicted there likely will be a government shutdown Friday night and put the onus on Democrats -- a reversal from his position just a week ago, when he said he would "take the mantle" and not blame the opposing party."The chances are probably very good" that there is a shutdown, Trump said to reporters Friday afternoon while at a White House bill signing on bipartisan legislation overhauling the nation's sentencing laws."It's really the Democrat shutdown, because we've done our thing," Trump continued. "Now it's up to the Democrats as to whether we have a shutdown tonight. I hope we don't, but we're totally prepared for a very long shutdown."Just a week ago, the President -- sitting in the Oval Office with House Minority Leader Nancy Pelosi and Senate Minority Leader Chuck Schumer -- said he would be "proud" to shut down the government over border security."I will take the mantle," Trump said last week. "I will be the one to shut it down. I'm not going to blame you for it."Earlier Friday, 3151

U.S. Senate candidate Roy Moore published an open letter to Sean Hannity on Wednesday night pushing back against allegations of sexual abuse that have placed his campaign at the center of a national firestorm and prompted prominent members of the Republican Party to call on Moore to withdraw from the race.In the letter, which came one night after Hannity said he would give Moore 24 hours to explain inconsistencies in how he has addressed the allegations before calling on him to step aside in the race, Moore suggested he was the victim of a political hit job."I am suffering the same treatment other Republicans have had to endure," Moore wrote Hannity.Moore faces accusations from multiple women that he pursued sexual relationships with them -- and in two cases engaged in sexual assault -- while they were between 14 and 18 years old and he was in his mid-30s.Moore denied dating underage girls, but only specifically addressed allegations from two of the women. He said "at the direction of counsel" he "cannot comment further."Moore said in his letter to Hannity that he was "in the process of investigating" what he characterized as "false allegations."On his program Tuesday night, Hannity demanded an explanation for a signature in a yearbook that appeared to have come from Moore. Despite Beverly Young Nelson -- one of the woman who accused him of sexual misconduct -- producing an old yearbook she said bore his signature, the embattled Senate candidate claimed he did not even know her."My signature on the order of dismissal in the divorce case was annotated with the letters 'D.A.,' representing the initials of my court assistant," Moore wrote Hannity. "Curiously the supposed yearbook inscription is also followed by the same initials—'D.A.' But at that time I was Deputy District Attorney, not district attorney."Moore added that he believed the "initials as well as the date under the signature block and the printed name of the restaurant are written in a style inconsistent with the rest of the yearbook inscription."The support of Hannity and other conservative heavyweights is crucial for Moore as he faces intense controversy. Thus far, Moore has responded to the allegations against him largely by dismissing them as supposed "fake news." If Hannity were to turn on him, it would signal to Republican voters in Alabama that there is merit to the allegations and that the reports in the media are not a political smear job as Moore has framed it.Hannity responded to Moore's letter at the end of his Wednesday night program and said that the allegations against Moore "are beyond disturbing and serious."But Hannity declined to drop his support for Moore, suggesting additional time and information is needed to render a decision. He ended his television show saying the decision ultimately lies with the people of Alabama and should not be decided by him or other conservative or Republican leaders."I am very confident that when everything comes out, they will make the best decision for their state," he said.  3054

URBANA-CHAMPAIGN, Ill. – As colleges and universities are tasked with safely beginning classes, researchers at one school are ramping up testing. But they're putting away the nasal swab in exchange for a test they say can be scaled to perform thousands of tests a day with turnaround in just hours.College junior Alliyah Rumbolt-Lemond is already back on campus and regularly testing for COVID-19.“I know if you have in-person classes, you're going to be on campus, you have to get tested twice a week,” she says.The college junior is one of the more than 51,000 students at the University of Illinois at Urbana-Champaign returning to school during the pandemic, posing a logistical challenge for administrators.“It was very daunting,” said U of I chemistry professor Marty Burke.He was part of the team of university researchers who developed a two-step saliva-based COVID-19 test to tackle the problem.“We called this our ‘target, test and tell’ initiative, overall collectively described as a ‘Shield.’”The Shield Initiative needed to be scalable, and unlike the four-step nasopharyngeal swab tests, not vulnerable to supply chain bottlenecks.“It's a very powerful concept that if we can get to that fast, frequent testing, we really could get control of the situation,” said Burke.A quick stop on route to class or work, integrated with local health care agencies, students receive results on an app within hours, not days.“It takes about five to ten minutes to submit your saliva sample and then the results are typically back on your phone within three to six hours,” said Burke.The university’s veterinary school diagnostic lab has been converted into a full-scale human COVID-19 testing facility. It’s capable of processing some 10 to 20,0000 saliva tests per day.“I want to hang out with friends and do it the right way, like following CDC guidelines,” said Alliyah. “But I feel more comfortable saying ‘hey when's the last time you got tested?’”A total of 20 testing sites with 40 stations are set up across campus. Users can even get exposure notifications if they’ve been in contact with someone who tests positive.“If someone tests positive then same day that person is isolated,” said Burke. “Which we think is critical for ultimately the efficacy of the testing program.”They’ve published a pre-print paper on their COVID-19 saliva test, which is undergoing peer review and are seeking FDA approval.For students like Alliyah, it’s one-stop piece of mind.“It makes you feel like I'm safer on campus because even though we only have to get tested twice a week you can get tested every day the testing site is open if you wanted to.” 2653

UPDATE: Suspect Brandon Alexander is in custody, and the Xavier Alexander and his mother are safe, Upland police say. They were found in Claremont, California, just west of Upland.SAN DIEGO (KGTV) - A 15-month-old child is missing, and police are looking for the child's father in connection with the abduction.The California Highway Patrol issued an Amber Alert Saturday night for a 2017 grey Jeep Renegade, California license plate 8DQT883.Authorities believe 31-year-old Brandon Alexander, may have kidnapped his son, 15-month-old Xavier Alexander. The pair were last seen at 5:45 a.m. Saturday in Upland, California, which is in San Bernardino County. Brandon Alexander is considered to be armed and dangerous.Brandon Alexander may have also taken the child's mother, according to Upland Police. Police say she is a white female in her early thirties. She has a restraining order against him, police said.Brandon Alexander is described as 5' 10" and 240 pounds with brown hair and blue eyes. Xavier Alexander is 2' 6" and weighs 30 pounds, also with brown hair and blue eyes. The Amber Alert was issued in Kern, Inyo, San Bernardino, Los Angeles, Ventura, Orange, Riverside, Imperial and San Diego counties.Anybody who sees the vehicle or Brandon and Xavier Alexander are asked to call 9-1-1.10News is monitoring this breaking situation. 1369

Vice President Joe Biden told reporters this week during a campaign stop in Pennsylvania that he would take a potential coronavirus vaccine even if it costs him the election.Biden’s comments come as questions are arising over the timing of a coronavirus vaccine as President Donald Trump continues to hint that a vaccine could be ready before Election Day – a claim many top health experts say is highly unlikely."We're going to have a vaccine very soon... maybe even before a very special date, you know what date I'm talking about,” Trump said on Monday.Biden in Pennsylvania expressed concern that Trump is undermining trust in the public health system. But conceded he too is ready for a vaccine.“One of the problems is the way he's playing with policy,” Biden said. “He says so many things that aren't true, I'm worried if we do have really good vaccine, people will be reluctant to take it. So he's undermining public confidence, but pray God, we have it. If I could get a vaccine tomorrow, I'd do it. If it cost me the election, I'd do it. We need a vaccine. We need it now."Although several vaccine candidates are in Phase 3 studies, leading public health experts suggest a vaccine would most likely be approved around the end of the year or early in 2021.In late August, the CDC told states to begin to prepare distributing a vaccine by Nov. 1. But Surgeon General Jerome Adams said that just because states will be ready to help distribute a vaccine on Nov. 1 does not mean a vaccine will be ready by then."We've always said that we're hopeful for a vaccine by the end of this year or the beginning of next year,” Adams told Good Morning America."We want to make sure states are available to distribute it," he added.Dr. Anthony Fauci, in an interview with NBC News last week, agreed that he believes a “safe and effective” vaccine could be ready by the end of the year."I believe that by the time we get to the end of this calendar year, that we will feel comfortable that we do have a safe and effective vaccine," he told NBC News. 2051

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