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On Monday morning, Pfizer announced that so far in Phase 3 trials, its COVID-19 vaccine candidate has been 90% effective in promoting protection against the virus. And while the announcement has many Americans seeing the light at the end of the tunnel, the pandemic is still far from over.Pfizer's announcement on Monday is an encouraging sign, as it means that the company is on track to file for Emergency Use Authorization for the vaccine in the coming weeks. It also keeps the U.S. on a timeline to have at least one vaccine approved and available for distribution by the end of 2021.But Monday's announcement does not mean a vaccine is imminent. Pfizer is currently mass-manufacturing its vaccine candidate in the event it does receive Emergency Use Authorization from the FDA, and hopes to have 100 million doses of the vaccine ready to ship by year's end. But even if Pfizer is able to fulfill that ambitious order by Dec. 31, it would only be able to vaccinate about one-third of everyone in the county.Once the initial vaccine order has been completed, it will need to be rationed for those who need it most — likely health care workers, essential employees and people in high-risk populations. While it is unclear who exactly will be eligible to receive the vaccine first, the Department of Health and Human Services (HHS) says the early distribution of a COVID-19 vaccine will be "constrained tightly" and will be "highly targeted" to "achieve coverage in priority populations."Eventually, the U.S. hopes to grant emergency use authorization to several vaccine candidates — many of which are currently in production on orders from the U.S. government. HHS hopes that by the middle of next year, several vaccines will be approved and widely available. But at that point, officials will run into a second major hurdle — vaccine skepticism.Skepticism about vaccines has been on the rise in recent years, fueled in part by the spread of misinformation online. In particular, baseless conspiracies linking vaccines to autism have spread on social media, eroding public confidence in medicine. In addition, polarized politics in the U.S. have led to speculation that government leaders will approve an unsafe or ineffective vaccine for political purposes.Vaccines are only effective if enough members of the public become inoculated against a virus — if a virus has nowhere to spread, it will eventually die out. But Gallup polling released in October shows that just 50% of Americans say they would receive a COVID-19 vaccine if it had been approved by the FDA and available at no cost — far below the threshold for herd immunity, according to many health experts.The Gallup polling is consistent with AP polling from earlier this year that also only found 50% willingness to take a COVID-19 vaccine.All the while, the final push for a COVID-19 vaccine will be occurring during what members of the White House coronavirus task force warn will be the most concerning and deadly period of the pandemic. The virus is currently spreading in the U.S. faster than it has at any other point during the pandemic, just as Americans are moving social gatherings indoors where the virus is more likely to spread.To be clear, health officials' efforts to develop a safe and effective COVID-19 is a momentous and historic achievement — approving a vaccine for emergency use by the end of the year would shatter all previous records for vaccine development. But while there may be light at the end of the tunnel, it may take several months — or years — to reach the end of the pandemic. 3586

OMAHA, Neb. — Authorities in Omaha say two people died and two others are in critical condition after a home explosion and subsequent fire early Tuesday morning.Following the deadly explosion, it was discovered that the homeowner, 74-year-old Theresa Toledo, had filed a petition for a domestic abuse protection order against 27-year-old Alexander Toledo, stating her relationship as his grandmother. Theresa and her daughter, Angela Toledo, both died in the fire that broke out in the 4800 block of South 51st Street. A dog also was found dead at the scene. According to the Omaha World Herald, Alexander and another person who lived in the home suffered critical injuries.Theresa wrote in the petition, "Alex is on meth, mushrooms that I'm aware of, I haven't been able to see my grandchildren since summer because they are afraid of him as he talks to himself and says his stepfather is in his head, which is not true...he has put holes in the basement walls where he stays and you can't even walk in the basement. He has electronics in the walls & ceiling. I'm afraid he will start my house on fire."Toledo also described her grandson's alleged criminal history with narcotics. She concluded the petition by writing, "I need Alex out of my house now before he destroys my house or harms me, the drugs make him crazy."According to Omaha Fire Department Battalion Chief Scott Fitzpatrick, crews arrived on the scene at 8:15 a.m. Tuesday, with a second alarm called at 8:23 a.m. The entire block was initially evacuated before authorities determined there was no threat to other residents.The house that exploded is a complete loss and was leveled in the explosion. Some surrounding homes have extensive damage.Neighbors described the scene as horrifying and said it sounded like a bomb went off. "I heard a very loud explosion. It sounded almost like something was bombed and I flew out of the house thinking it was my house and when I got outside I could see the house was on fire and someone was running down the hill and saying to call 911," said Marianne Distefano, a neighbor. When fire rescue arrived at the scene, the house was engulfed in flames. "It was horrible. I mean it was just in flames and after that, smoke, but you could see it was bad. It looked like someone had bombed the house," Distefano said. Distefano saw one neighbor jump to action. Jeff Mell ran towards the flames when he saw what was happening. "I heard something fall, it sounded like something fell on our house, I thought it was a tree or whatever so I came out front angry and I looked down the street and saw flames coming and I automatically just started running," Mell said. He and another neighbor wrapped a man in blankets and helped him to a safer area. Fire investigators are probing the cause of the explosion. "There are so many variables to tell right now, that’s why we have to investigate and kind of piece it together to see exactly what it was that made that house explode. As you can see, the explosion was pretty big," said Fitzpatrick. The fire department said that this will be a lengthy investigation.Read related court documents filed on Monday below.This story was originally published by Alyssa Curtis, Danielle Meadows, Katrina Markel and other staff at KMTV. 3280

OCEANSIDE, Calif. (KGTV) - An Oceanside family is grieving the loss of a 18-year-old honors student discovered dead from an overdose linked to fentanyl.For big sister, Jill, and dad, Duncan, it's hard to think of life without Brianna Moore."It's hard to talk about. She's my little sister," said a tearful Jill."We miss her so much. She had a bright future ... She was always so motivated," said Duncan.By the age of 14, Briana had run two marathons. She excelled at soccer and the violin. The honors student was accepted into a scholarship program at Stanford this summer but had to withdraw due to mental health issues, including depression.Amid the recent protests aimed at racial injustice, Brianna was called to action."She was inspired by the movement. She wanted her voice to be heard," said Jill.Her participation took her to Los Angeles."She started off with a good crowd that wanted to help people, and over time, she just met the wrong people," said Jill.Brianna was due back home Aug. 11 for orientation at Cal State San Marcos, but she never made it home.Inside a park in Echo Park, Los Angeles, a memorial marks the area where on Aug. 9, Brianna's body was discovered in a tent. The family says they were told by the medical examiner's office that Brianna died from an overdose: cocaine secretly laced with fentanyl.Earlier this month, law enforcement officials issued a warning about a large local spike in deaths linked to the synthetic opioid fentanyl. Experts say amid the COVID-19 pandemic, people may turn to substance abuse to deal with stress. Brianna's family suspects she recently began experimenting with drugs. They hope by sharing her story, they can help others."Just takes one time, one slip-up. You never know what you’re getting, and you ever know what you’re getting into ... It really hurts the people around you," said Jill.A GoFundMe campaign has been set up to help the family with expenses. Loved ones are hoping to donate part of the proceeds to efforts aimed at mental health issues. 2030

OCEANSIDE, Calif. (KGTV) -- The mother of one of the 15 Marines injured in a fiery training accident at Camp Pendleton said she panicked when she learned her son was one of the wounded.RELATED: Officials: 15 Marines injured in Camp Pendleton training accident“It made my heart hurt to see him for sure, you know, with his face all burnet and knowing how bad burns hurt,” said J.R. Koontz, mother of Marine Samuel Koontz.Fifteen members of Charlie Company with the 1st Battalion, 1st Marine 3rd Amphibious Assault Battalion were hurt when the AAV they were in exploded during a training exercise on land.RELATED: Report indicates Camp Pendleton fire caused by gas lineA photo posted to social media shows an AAV in a ditch engulfed in flames.“He’s burnt on his face, and his ear and his hand. And he’s got a few abrasions here and there,” J.R. Koontz said of her son, who was released from the hospital. “He seems to be healing pretty well."J.R. Koontz said she flew to San Diego the morning after the accident and visited her son at UCSD Medical Center in Hillcrest.“It was really comforting because there was like eight Marines there in uniform. They stood there all night. They never leave him alone,” she said.Samuel Koontz posted on Facebook he has second and third-degree burns to his face but won’t have permanent scars.He wrote the vehicle, also called a Track, “Exploded and the track caught fire, me and my squad exited out multiple ways some being injured more than others. Me and some of my squad mates got out and went back to pull the rest of our brothers out that couldn’t do it for themselves for various reasons.”He also asks people to pray for the Marines still hospitalized and some badly injured.“it’s just kind of a traumatic thing I think when you go through something like that,” J.R. Koontz said. “I believe they put all the guys that were hurt in the accident in the wounded warrior battalion so that gives them time to go over what happened."The Marine Corps is not paying the flights and hotel stays for the families visiting the injured Marines. The Newport Beach 1st Marines 1st Battalion Foundation is picking up those bills to help the families.“They paid for our hotel when we were up there and our flight to get back,” she said on the phone from her home in Washington state. “That was really unexpected and really, really nice.”If you would like to donate, the Foundation asks you do so on their website.  2486

OCEANSIDE, Calif. (CNS) - Police identified a 43-year-old man armed with a machete who allegedly stabbed a police dog and broke a patrol vehicle's window in Oceanside.About 5 p.m. Tuesday, an officer was inside a vehicle, stopped at a traffic light on College Boulevard and Plaza Drive, when he saw the suspect, Noomane Trabelsi, across the street yelling at him, according to Oceanside Police Department Public Information Officer Tom Bussey.The suspect allegedly approached the vehicle swinging a machete and broke the driver's side window, Bussey said.The officer suffered minor injuries and called for assistance. A perimeter was established, and the suspect was seen near the Mossy Nissan dealership, at 3535 College Blvd., and officers tried to make contact with him, according to Bussey.Trabelsi went into a nearby ravine, prompting officers to deploy a police dog, according to Bussey.Trabelsi allegedly stabbed the dog, named Chico, in his head and then stabbed himself multiple times in his stomach, Bussey said. Chico was taken to a veterinarian and is expected to recover, according to Bussey.Officers, assisted by a San Diego County Sheriff's Department helicopter, searched for Trabelsi for two hours in tough terrain, according to Bussey.Trabelsi was located, arrested and taken to Scripps La Jolla to be treated for the self-inflicted injuries, Bussey said. 1381

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