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The month of March for Diana Berrent was one she could’ve done without. The 46-year-old woman was one of the first people in New York State to catch COVID-19.To this day, she's still living with residual symptoms six months later.“COVID is supposed to go away like the flu, and it’s not necessarily going away after two weeks,” she explained.In an effort to help find treatments and develop a vaccine, Berrent has been donating plasma as often as she can. It's in her antibodies, where the key to fighting this virus may lie.Dr. Wesley Self, a researcher at Vanderbilt University Medical Center, has spent the last few months trying to figure out what antibodies are telling us about COVID-19 and how to fight it.“Understanding how the immune system responds to the virus will help development of the vaccines,” Dr. Self said.Dr. Self and his colleagues spent the last few months studying 3,000 people. All of them were healthcare workers who had tested positive for COVID-19. They found that a majority of people who had the most severe cases started out with the most antibodies. But the study also found after 60 days, almost everyone who had coronavirus lost all antibodies.That could be bad news when it comes to our bodies' ability to fight off the virus a second time.“The antibodies are one piece of the immune system. It’s possible they’ll ramp up again quickly and prevent reinfection,” Dr. Self added.All of this also means researchers now need to get blood samples from people fairly quickly after they're infected before antibodies disappear.“We need to be thoughtful about vaccines and treatments that are specific for this virus,” he said. 1662

The Indianapolis 500 will be held without fans in attendance on Aug. 23 due to escalating concerns over the coronavirus pandemic in Marion County, the Indianapolis Motor Speedway announced Tuesday.It will mark the first time in the 109-year history of the Indy 500 that it will be run in front of empty stands at the 2.5-mile oval track.“As dedicated as we were to running the race this year with 25 percent attendance at our large outdoor facility, even with meaningful and careful precautions implemented by the city and state, the COVID-19 trends in Marion County and Indiana have worsened," a news release from IMS said.First held in 1911, the Indianapolis 500 is the largest single-day sporting event in the world with approximately 350,000 people annually packing the track's grandstands and infield to watch "The Greatest Spectacle in Racing." Running the race without fans prevents the seventh cancellation in Indy 500 history. The race was not held in 1917-18 during World War I, and from 1942-45 during World War II.In late March, IMS leaders rescheduled the race from May 24 to Aug. 23. Officials said on June 26 that Indy 500 attendance would be limited to no more than 50%.That number was further decreased on July 22 when plans were scaled back to host the race at 25% capacity. Face coverings would be required, and the Speedway released an 88-page health and safety plan that provided guidelines and protocols for how the race would be run in 2020.Even at 25% capacity, the race would have been the largest event held in the United States since the beginning of the coronavirus pandemic.IndyCar and IMS owner Roger Penske previously said he wouldn't run the race without fans, but the realities of the pandemic prevailed.“We need to be safe and smart about this,” Penske told the Associated Press. “Obviously we want full attendance, but we don’t want to jeopardize the health and safety of our fans and the community. We also don’t want to jeopardize the ability to hold a successful race.”In a news release, IMS said in the weeks since the June 26 announcement of 50% capacity, the number of COVID-19 cases in Marion County has tripled while the positivity rate has doubled."We said from the beginning of the pandemic we would put the health and safety of our community first, and while hosting spectators at limited capacity with our robust plan in place was appropriate in late June, it is not the right path forward based on the current environment," the release said.How fans will be impactedThe announcement of no fans on race day also means all on-track activity during the month of August, including practice and qualifications, will be closed to the public. The first practice will take place on Aug. 12.Fans who still have tickets to the 2020 Indy 500 will be credited for the 2021 race and retain their seniority and originally assigned seats.Additionally, as announced in July, the race will be broadcast live on TV in Central Indiana for the first time since 2016.State and city leaders react to Speedway's decisionIndiana Gov. Eric Holcomb issued a statement following the announcement thanking Penske and IMS leadership and encouraging Hoosiers to do what they can to prevent the spread of COVID-19. 3239

The holiday shopping season got off to a hot start on Friday as consumers flooded into stores and logged onto e-commerce sites in search of deals.Real-time figures from Mastercard show that overall sales are poised to hit billion on Black Friday alone. That's up about 9% from the day after Thanksgiving last year.Mastercard projects that overall holiday sales from November 1 through Christmas Eve should grow by 5% this year."We've gotten off to a very good start," said Steve Sadove, Mastercard senior advisor. "Both online and in-store sales are both tracking very well."More and more Black Friday shoppers are turning online to score discounts and deals.Adobe, which tracks online sales, reported that online purchases were up nearly 28% in the early hours of Friday morning.Very cold weather in the Northeast might be helping online sales growth on Friday, Mastercard's Sadove said.Electronics are a hot sellers. Adobe reported that the Nintendo Switch is the most popular item online, and Sadove said the new line of digital assistants and smart home products are attracting buyers.The strong holiday sales are being fueled in part by a healthy economy, which features low unemployment and some gains in average income. High levels of consumer confidence also help.In addition, the calendar is favorable for a strong holiday shopping season. Thanksgiving came earlier this year, and Christmas falls on a Tuesday. That schedule is expected to result in Sunday December 23 sales that match Black Friday sales figures.Without Toys "R" Us, which went out of business this past year, many retailers are looking for a toy boost.Sadove refers to as a "land grab" of retailers trying to up their toy offerings as a way to attract shoppers.Beyond the leaders - Walmart, Target and Amazon - Best Buy is also making a major push to sell toys. And grocer Kroger's is offering toys using the old Toys "R" Us Geoffrey the giraffe mascot with its "Geoffrey's Toy Box." 1972

The original cast of "Hamilton" is reuniting Friday for a virtual fundraiser for Democratic presidential nominee Joe Biden.Cast members will include creator Lin-Manuel Miranda and Daveed Diggs, Renée Elise Goldsberry, Jonathan Groff, and Leslie Odom, Jr. as part of a special "grassroots fundraiser" for the Biden Victory Fund.The cast will participate in a Q&A that will be moderated by director Thomas Kail. Cast members will then entertain with a performance afterward.The fundraiser begins at 9 p.m. ET, and any donation is accepted to join the event. 567

The Pittsburgh Steelers have placed four more players on the COVID-19 list, including quarterback Ben Roethlisberger. According to the Associated Press, a player is added to the reserve/COVID-19 list if they have tested positive for the virus or have been in close contact with someone who has it.The move comes a day after tight end Vance McDonald went on the list after testing positive following a 24-19 win at Dallas that pushed the Steelers to 8-0. Running back Jaylen Samuels, offensive lineman Jerald Hawkins, and linebacker Vince Williams joined Roethlisberger on the list Tuesday.According to ESPN, the players are considered high-risk contacts, so they must isolate for five days after their last contact with McDonald, and they can't be at the team's practice facility during those five days.The team will test the players throughout the week before they are deemed eligible to play against the Cincinnati Bengals on Sunday, ESPN reported.According to ESPN, Roethlisberger has been seen not wearing a mask when talking to McDonald while on the sidelines. The teammates also have lockers close to each other. Roethlisberger has not tested positive, ESPN reported.For the first time in the team’s history, the Steelers are 8-0. 1244

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