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Former UN Secretary-General and Nobel Peace Prize winner Kofi Annan has died at age 80, his foundation confirmed Saturday.Annan, who was born in Ghana in 1938, served as the seventh UN Secretary-General, from 1997 to 2006, and was the first to rise from within the ranks of the United Nations staff.He had also been a member, since 2007, of The Elders, a humanitarian group of a dozen leaders and activists of worldwide stature formed by Nelson Mandela. In 2013, Annan became its chairman.The Kofi Annan Foundation confirmed his death with "immense sadness" in a statement posted on Twitter.Annan passed away peacefully Saturday morning after a short illness, with his wife Nane and their three children by his side during his final days, the statement said. 766

Former Trump campaign chairman Paul Manafort sought a plea deal before his trial in Washington, DC, federal court next month, but talks stalled over issues raised by special counsel Robert Mueller, The Wall Street Journal reported Monday, citing people familiar with the matter.Manafort was found guilty last Tuesday in a separate trial in Virginia federal court on eight counts of financial crimes, including tax fraud, bank fraud and hiding foreign bank accounts. He faces a second set of criminal charges next month in Washington of failure to register his foreign lobbying and money laundering conspiracy.The talks between the defense and prosecutors occurred last week as the Virginia jury was deliberating, people familiar with the matter told the Journal. The newspaper said it was unclear what issues Mueller raised or what terms for a potential plea might have been proposed.Representatives for Manafort and Mueller declined to comment to the Journal.The second trial is scheduled to begin on September 17 and is also related to Manafort's political consulting work in Ukraine. Mueller's office has almost three times as many exhibits?it wants to show a jury as it did in the Virginia case, indicating how expansive Mueller's investigation of Manafort has been. 1298

For the first time in more than a decade, a new treatment to improve brain function for Alzheimer’s disease has been submitted to the Food and Drug Administration (FDA) for review.This was after the drug trial was stopped and then a second look revealed some promising results.The Waterhouse family has seen the impact of Alzheimer’s firsthand.Gina and Steve Waterhouse have been a team most of their lives. They’ve been married for 43 years and ran several businesses together. Then in 2016, things started to change. Gina didn’t notice anything but employees at the family's businesses did.“I wasn't remembering some of the stuff I was supposed to be doing,” said Gina.Gina was diagnosed with early Alzheimer's disease that year.“They said, 'well you can come back in a year. We will check and see how you're doing, or we have a drug trial if you're interested,'” said Gina.Gina and Steve spent the next two and a half years at the Mayo Clinic, where Gina eventually got high doses of the drug aducanumab.Steve started to notice Gina was remembering more things and reported it back to doctors.“He just smiled and said, 'let me tell you what we're seeing. We're seeing cognitive improvement. And it’s the first time in my career.' These doctors said in their career that we've ever seen it,” said Steve.“He was so excited,” said Gina.Then in 2019, the drug trial suddenly ended. Gina says she felt like she’s gone downhill a little since it did.Rebecca Edelmeyer, PhD, with the Alzheimer’s Association, says the trial stopped early based on a futility analysis.“It was a statistical analysis that was done by the Biogen team, predicting that the trial would not actually be successful,” said Edelmeyer.Edelmeyer says then upon a second look at the trial data, they found that those people on the highest dose of the drug were seeing improvement in their brain function. She called it a very important moment for the Alzheimer’s research community.Now, the government will determine whether or not the drug is safe and effective enough to use.Steve mentioned there were some possible side effects like bleeding of the brain, but Gina did not experience any.Meanwhile, Gina can no longer take the drug. She and Steve have decided to retire.“We just decided tomorrow has to come today and we're having a great time. We're loving life,” said Gina.You can learn more about aducanumab here. 2394

Former first lady Michelle Obama discusses her dislike of President Donald Trump — as well as personal details of her life before and during her time in the White House — in her highly anticipated memoir, "Becoming," The Washington Post reported Thursday.Obama says she would "never forgive" Trump for the rumors he spread questioning the legitimacy of President Barack Obama's American birth certificate, which she said threatened her family's safety."The whole [birther] thing was crazy and mean-spirited, of course, its underlying bigotry and xenophobia hardly concealed. But it was also dangerous, deliberately meant to stir up the wingnuts and kooks," she writes, according to the Post, which obtained an early copy of the book. It will be released next Tuesday."What if someone with an unstable mind loaded a gun and drove to Washington? What if that person went looking for our girls?," she adds. "Donald Trump, with his loud and reckless innuendos, was putting my family's safety at risk. And for this I'd never forgive him." 1041

For the first time in its history, Sports Illustrated will feature a transgender model in its annual Swimsuit Edition.Sports Illustrated said Friday that 23-year-old Brazilian model Valentina Sampaio would be featured in the magazine, which is slated for a July 21 release.In an open letter published on Sports Illustrated's website, Sampaio said she was "excited and honored" to be a part of the upcoming issue."Being trans usually means facing closed doors to peoples’ hearts and minds," she wrote. "We face snickers, insults, fearful reactions and physical violations just for existing. Our options for growing up in a loving and accepting family, having a fruitful experience at school or finding dignified work are unimaginably limited and challenging.""I recognize that I am one of the fortunate ones, and my intention is to honor that as best I can."According to NBC, the Swimsuit Edition is just the latest barrier Sampaio has smashed as a transgender model. Last year, she was hired as the first openly trans Victoria's Secret model, and she was the first openly trans model to appear on the cover of any Vogue magazine."Valentina has been on our radar for some time now and when we finally met face-to-face it became apparent that besides her obvious beauty, she is an impassioned activist, a true pioneer for the LGBT+ community and just simply embodies the well-rounded woman we are proud to have represent SI Swimsuit across our platforms," Sports Illustrated said in a statement to NBC.In 2019, Sports Illustrated featured a Muslim model, Halima Aden, in the Swimsuit Edition. Aden sported a hijab and a burkini in her photo shoot. 1653

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