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The United Kingdom says it will be the first to conduct COVID-19 vaccine human challenge trials.It's different than other vaccine studies. People will be deliberately infected with the virus, which speeds up the research process.Pending approval, the process will start in January at a London hospital. It will require about 90 healthy young adults between the ages of 18 and 30.The group 1 Day Sooner has recruited from all over the world, including 3,000 Britons.“If the vaccine works, then ideally, people don't get infected and if people do, then they will be closely monitored and treated, but because these are young and healthy people taking part in the trial, I think, researchers feel comfortable doing so because the risks of death are on par with something like kidney donation for people who are young and healthy,” said Abie Rohrig with 1 Day Sooner.Before researchers test the vaccine, they'll do a characterization study. That's where volunteers are infected by getting a vaccine to determine the right amount of virus to give during the trial.Because of the risk, 1 Day Sooner is advocating for the entire process to be made public.Results could come in May. Even though that's likely after other COVID-19 vaccines are licensed, it's still important because we need billions of doses and because of the unique data human challenge trials provide.“Researchers can understand how the virus works in the human body. They can understand the biological markers of immunity. In fact, much of our understanding of other types of coronaviruses come from challenge studies that were conducted in the 1960s in Britain,” said Rohrig.Human challenge volunteers are paid and monitored for at least a year after. 1722

The school shooting was over in seconds. But it could have dragged on longer and proven deadlier were it not for the rapid response of a school resource officer.When a 17-year-old gunman walked into Maryland's Great Mills High School on Tuesday, the swift action of the school's sole resource officer, Blaine Gaskill, was instrumental in bringing the incident to a quick end.Gaskill's response was hailed as an example of exactly what a resource officer is supposed to do in such a circumstance, particularly when contrasted to the actions of the security officer in last month's shooting in Parkland, Florida. (In the incident at Marjory Stoneman Douglas High School on February 14, the armed school resource deputy waited outside the school building as the shooter gunned down students inside.)"He responded exactly how we train our personnel to respond," St. Mary's County Sheriff Tim Cameron told reporters.Engaging the shooterAs soon as the gunfire began, Gaskill rushed to the scene. He fired a round at the shooter, who also fired a round at the same time, Cameron said.It's not yet clear whether the shooter, Austin Wyatt Rollins, was felled by the officer's bullet or killed himself."DFC [Deputy First Class] Gaskill fired at the shooter ... almost simultaneously as the shooter fired," Cameron said. "This is something we train, practice and in reality, hope would never come to fruition. This is our worst nightmare."Gov. Larry Hogan called Gaskill "a very capable school resource officer who also happened to be a SWAT team member.""This is a tough guy who apparently closed in very quickly and took the right kind of action," he said. "And while I think it's still tragic, he may have saved other people's lives."Over in secondsThe incident began in a school hallway at 7:55 a.m., just before classes started. Authorities say Austin, armed with a handgun, shot a female student, with whom he had a prior relationship, and another male student.Gaskill responded to the scene in less than a minute, the sheriff said.Cameron said the entire incident took less than a minute, possibly seconds.The 16-year-old female student is in critical condition with life-threatening injuries, and the 14-year-old male student who was shot is in stable condition.Gaskill was unharmed."He's doing well and we're going to do everything to support and promote him and his well-being," Cameron said.Playing to a narrativeGaskill's actions were praised, rightly, across social media. But some -- most notably, the NRA -- held him up as an example of the "good guy with a gun" theory. The theory goes, that bad guys will always find a way to circumvent whatever gun laws are in place. And "to stop a bad guy with a gun," as NRA head Wayne Lapierre?said, "it takes a good guy with a gun.""This [Great Mills High School] armed school resource officer, you're not hearing anyone in #MSM talk about it because it disrupts their narrative," NRA spokeswoman Dana Loesch said in one of several tweets Tuesday. (MSM is short for mainstream media.)So far, this year, there have already been 17 school shootings where someone was hurt or killed.In the Parkland shooting, school resource deputy Scot Peterson never entered the building after taking a position outside. He resigned after he was suspended without pay for his inaction."Had our resource officer taken action immediately, the result of the Stoneman Douglas Valentine's Day Massacre would have been different," Parkland student Kai Koerber told CNN."We might not have had to walk over the bodies of our classmates, once lovely and wonderful people, as we were led away from murderous tragedy."Speaking to reporters, Dr. James Scott Smith, the superintendent of St. Mary's County's public schools, put the senselessness of it all in perspective."It looks as though the SRO [school resource officer] did exactly what the SRO is trained to do, and yet we still have a tragic loss of life," he said. "We still have somebody in critical condition. And we have students at the school and staff at the school impacted." 4086

The Tulsa Athletic, a semi-pro soccer team in Oklahoma, announced on Wednesday that they will no longer play 'The Star-Spangled Banner' before home matches.Team officials said they want to ensure an inclusive environment for athletes, supporters, and the community. 273

The release of three US nationals currently detained in North Korea is "imminent," according to an official with knowledge of the ongoing negotiations.The official told CNN the North Koreans made the decision to free the Americans two months ago, and that North Korea's Foreign Minister Ri Yong Ho had proposed their release during his visit to Sweden in March.US officials insisted at the time that their release "must not be related or used to loosen the main issue of denuclearization," the source said. 519

The road to the White House clearly goes through the state of Michigan as both Joe Biden and Donald Trump have been actively campaigning in the state.Michigan has been a state hard-hit economically in recent years as the once thriving auto industry Nationally, the number of auto jobs has declined amid the pandemic. The auto industry has lost nearly 100,000 jobs this year.At the start of the century, there were more than 1.3 million US auto jobs. When Barack Obama took office, that number had dropped by 50%. During his tenure, the auto industry regained a portion of those jobs lost.But any gains from a revamped trade agreement had yet to be realized in the auto industry based on Bureau of Labor Statistics figures. On Thursday, Joe Biden said in an interview with CNN’s Jake Tapper the new USMCA agreement that replaced NAFTA is an upgrade, but failed to give President Donald Trump for securing the agreement."But look what the overall trade policy has done even with NAFTA. We now have this gigantic deficit in trade with Mexico. Not because NAFTA wasn't made better, because overall trade policy and how he deals with it made everything worse," Biden said.Biden was asked whether Trump should be given credit for the USMCA. Biden said the Obama White House was unable to renegotiate NAFTA because of Congress. For the first two years of the Obama administration, both the House and Senate were held by Democrats.“Because we had a Republican Congress that wouldn't go along with us renegotiating,” Biden told Tapper.In 2008, both Biden and Obama campaigned on changing the US trade agreement between Mexico and Canada. The USMCA, which became effective this year, was amended by Congress, but ultimately won bipartisan support from leaders of both party.The interview with Tapper was taped in Michigan and aired hours before Trump held a campaign rally in the state.On Monday, Trump said, “Biden supported NAFTA. He supported China’s entry into the World Trade Organization. Two disasters. The most disastrous trade deals in history, both of them. I can’t tell you which was worse; they were both terrible.” 2125