呼市哪能治肛瘘(呼市长痔疮疼吗) (今日更新中)

CHICAGO — Millions of frontline healthcare workers are rolling up their sleeves for the first of a two-dose COVID-19 vaccine. First out is Pfizer’s vaccine, and now, an FDA panel has recommended Moderna’s vaccine for emergency use authorization. The available Pfizer shot requires a complex and precise procedure for it to work.Before the needle even breaks the skin, a strict protocol must be followed precisely.“We're going to put it take it from the negative 80 ultra-low storage and we're gonna defrost it to refrigerator temperatures,” explained Erin Shaughnessy, director of pharmacy at Rush University Medical Center in Chicago. “That's gonna give us five days of stability for the vaccine.”It’s like something out of Mission Impossible.“We installed additional security cameras and we have additional security protocols,” said Shaughnessy.She’s charged with ensuring the vaccine is securely handled and properly prepped before it’s injected.“We don't want to risk wasting any of the drugs,” she said. “The stuff is liquid gold right now.”That liquid gold must be stored at 80 below zero, in a secure location that only a few pharmacists have access to.“We have to take it out of the ultra-low freezer and move it to a refrigerator just to thaw for three hours.”Once thawed, it cannot be re-stored.“You can't put the medication back into the freezer,” said Shaughnessy. “Once inside, you have to use it or you're going to lose it. It's gonna have a five-day refrigerated expiration.”Pfizer’s vaccine protocol also requires the vaccine to be protected from UV light and the dilution must be gently inverted exactly 10 times. Shaken too hard, says Shaughnessy, and it could go bad.“It's very, very specific," she explained.That’s when the clock starts ticking.“Once they're thawed and reconstituted, basically diluted down to make the actual doses, then that's when we have six hours on the clock going from that dilution point into someone's arm,” said Luke Hvass, a clinical pharmacist at Rush.Each dose is recorded and logged. It’s a symphony of procedures that must come together like clockwork.“It's a lift for a lot of hospitals, a lot of organizations, but I think it's a challenge everybody is ready to rise to because everyone is so excited about getting this vaccine process started,” said Shaughnessy.The Department of Health and Human Services has expanded the scope of who can act as vaccinators. In addition to pharmacists, interns, pharmacy students and pharmacy technicians who complete 20 hours of training will be added to the vaccination workforce to help handle the massive undertaking. 2619

CAMBRIDGE, Mass. – The U.S. government will pay Moderna Inc. up to .525 billion to secure 100 million doses of the company’s COVID-19 vaccine candidate.The U.S. Department of Health and Human Services (HHS) and Department of Defense (DoD) made the announcement Tuesday.HHS says Moderna will manufacture the vaccine doses while clinical trials are still underway to expedite the traditional development timeline and get vaccines to the public as soon as possible.The Trump administration hopes to deliver the vaccines by the end of the year, so long as the U.S. Food and Drug Administration (FDA) authorizes their use.“In creating a vaccine portfolio for Operation Warp Speed, the Trump Administration is increasing the likelihood that the United States will have at least one safe, effective vaccine by 2021,” said HHS Secretary Alex Azar. “Today’s investment represents the next step in supporting this vaccine candidate all the way from early development by Moderna and the National Institutes of Health, through clinical trials, and now large-scale manufacturing, with the potential to bring hundreds of millions of safe and effective doses to the American people.”HHS says the vaccine doses will be delivered to government-designated locations across the country and the U.S. could acquire up to an additional 400 million doses of the vaccine.If viable, the vaccines would be available to the American people at no cost, according to HHS. Healthcare professionals could charge for the cost of administering the vaccine, though.The vaccine, called mRNA-1273, has been co-developed by Moderna and scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The third phase of the vaccine trial, which began July 27, is the first government-funded Phase 3 clinical trial for a COVID-19 vaccine in the nation, according to HHS.“We appreciate the confidence of the U.S. government in our mRNA vaccine platform and the continued support,” said Stéphane Bancel, Moderna’s Chief Executive Officer. “We are advancing the clinical development of mRNA-1273 with the ongoing Phase 3 study being conducted in collaboration with NIAID and BARDA. In parallel, we are scaling up our manufacturing capability with our strategic partners, Lonza, Catalent and Rovi, to address this global health emergency with a safe and effective vaccine.” 2402

Canada is the latest country to approve a COVID-19 vaccine candidate made by Pfizer and BioNTech, according to ABC News and the Washington Post.On Monday, Prime Minister Justin Trudeau announced that the vaccine would arrive in Canada next week and that doses would be distributed at that time.The FDA is expected to meet tomorrow to discuss granting Emergency Use Authorization to the Pfizer vaccine. Approval is expected, and Americans may begin receiving doses as soon as next week.The drug has already been administered to some patients in the United Kingdom, who approved the vaccine for emergency use last week. On Wednesday, officials announced that two people with extensive histories with allergies had suffered "adverse effects" from the injections, but both patients are expected to be OK. Officials in the U.K. are now advising patients with similar histories of extreme allergic reactions to not get vaccinated for the time being.Initial efficacy studies showed the Pfizer vaccine to be 95% effective in preventing COVID-19, without serious side effects.A vaccine candidate made by Moderna is also on the precipice of receiving widespread approval from several major western countries. 1206

BURBANK, Calif. (AP) — Traffic was backed up for miles for thousands of drivers Friday night on a busy Los Angeles-area freeway after a chase that lasted well over an hour and saw the driver repeatedly back into police cruisers.At one point after backing into a cruiser, the man gestured from his window with what appeared to be a knife.The man drove onto Interstate 5 in Burbank the wrong way, eventually passed a police barrier and rammed into several cars before stopping.Police evacuated drivers from their cars while they had their guns trained on the car. The driver eventually got out. It appeared that officers used a stun gun on him, prompting him to get back into the car.A standoff pursued and eventually ended after the man got out of the car, laid down for a while and tried to run away. He was arrested. 825

CAMP PENDLETON, Calif., (KGTV)-- Thousands of US Marines stormed a makeshift town today as part of the largest amphibious exercise in Camp Pendleton's history. With their guns drawn and light on their feet, the Marines at Camp Pendleton have one objective: secure the Red Beach Combat Town. The town is a collection of makeshift structures off Las Pulgas Road just west of Interstate 5.The scenario was this: The soldiers are fighting the enemy from a near-pier threat. The Marines got battle-ready at sea, aboard the USS Somerset and USS Macon Island, thanks to their special partnership with the US Navy. "We spend a lot of time on ship, a lot of time coordinating with the sailors themselves inside the welded deck inside the ship," Amphibious Assault [AAV] Section Leader, Sgt. Kenneth Larkin said. "Being able to rely on each other for the safety of our vehicles and our members, it's phenomenal."From ship to shore, the men and women arrive on their AAV. They creep onto shore at seven mph, then book it on land. The crew drops off the infantry, ant the combat simulation begins. This scenario kicks off this year's Steel Knight Exercise. With 13,000 Marines and sailors participating, it is the largest iteration of the Steel Knight Exercise at Camp Pendleton."The Marine Corps prides itself on being amphibious, so this is one of those exercises where the division gets involved. The entire division of Camp Pendleton," Infantry Platoon Sgt. Ethan Rhoades said. "It basically hones our skills to actually go from ship to shore and to seize an objective likely would in a real-time conflict."For two weeks straight, the men and women will repeat the aerial and amphibious exercises. Tough training in the elements will prepare them for real-life scenarios. "Just know that America's sons and daughters are working hard in the First Marine Division to prepare to win this nation's battles," 1st Marine Division Spokesperson, Lt. Cameron Edinburgh said. "This what we're trained to do. And get it done no matter what happens," Sgt. Rhoades said. 2061

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