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WASHINGTON, Oct. 3 (Xinhua) -- The Rockefeller University confirmed Monday its Canadian-born cell biologist Ralph Steinman died three days before being awarded the Nobel Prize on Monday as the Nobel committee was unaware of his death at the time."Steinman passed away on September 30," the New York university said in a statement."He was diagnosed with pancreatic cancer four years ago, and his life was extended using a dendritic-cell based immunotherapy of his own design."The Nobel committee was unaware of Steinman's death when announcing this year's winners and it was unclear whether the prize would be rescinded because Nobel statutes don't allow posthumous award."The Rockefeller University is delighted that the Nobel Foundation has recognized Ralph Steinman for his seminal discoveries concerning the body's immune responses," says Rockefeller University President Marc Tessier-Lavigne."But the news is bittersweet, as we also learned this morning from Ralph's family that he passed a few days ago after a long battle with cancer. Our thoughts are with Ralph's wife, children and family.""We are all so touched that our father's many years of hard work are being recognized with a Nobel Prize," says Steinman's daughter Alexis. "He devoted his life to his work and his family, and he would be truly honored.""Ralph's research has laid the foundation for numerous discoveries in the critically important field of immunology, and it has led to innovative new approaches in how we treat cancer, infectious diseases and disorders of the immune system," Tessier-Lavigne says.Steinman, who discovered the immune system's sentinel dendritic cells, is this year's recipient of the Nobel Prize in Physiology or Medicine. He shares half the prize with Bruce Beutler and Jules Hoffmann.
BEIJING, Nov. 22 (Xinhuanet) -- Women aged 40 to 49 are not recommended for routine mammography screening for breast cancer, said the new guidelines issued by the Canadian Task Force on Preventive Health Care in media reports Tuesday.The new guidelines are purposed to direct doctors on using mammography, MRI scans, clinical breast exams and breast self-exams. In principle, they pointed out, there is no need for women to take clinical breast exams and breast self examination if there are no signals for breast cancer.Below are the main points from the guidelines which need special attention from women with reasonable doubt on the matter:Women aged 40-49 who have lower risk for cancer should not take routine mammography because of the higher risk for overdiagnosis, overtreatment and false-positives;Women aged 50 to 69 years and aged 70 to 74 years should go for routine screening every two to three years;And there should be no routine clinical breast exams by doctors and no breast self-exams to screen for breast cancer.Dr. Marcello Tonelli, Chair of the Task Force and Associate Professor at the University of Alberta, remarked: "The main effect of screening is to produce patients with breast cancer from among healthy women who would have remained free of breast disease for the rest of their lives had they not undergone screening.""The best method we have to reduce the risk of breast cancer is to stop the screening program," he added, "This could reduce the risk by one-third in the screened age group, as the level of overdiagnosis in countries with organized screening programs is about 50 percent."
WASHINGTON, Nov. 25 (Xinhua) -- In the United States, the AIDS epidemic has plateaued, but it is still at "unacceptable high" level, a U.S. expert said ahead of the World AIDS Day."The situation is stable in the United States, stable in an unacceptable high level for at least 10 years and has not gone down. It's still a serious problem," Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), told Xinhua in an exclusive interview.According to Fauci, there are about 1.1 million people infected with HIV in the U.S., of which about 20 percent do not know they are infected. Those are the ones that more likely will infect other people. Since the world's first AIDS case was reported 30 years ago, the U.S. has seen close to 600,000 AIDS-related death. And among the 65,000 new infections each year in the U.S, about 50 percent are African Americans. In the United States, about 12 percent of the population is African American."Our new approach to prevention is to try and get access at community level, to people at most risk, to seek out to voluntarily test, to link them to care, and to automatically get them treatment," said Fauci. "When you get someone on treatment, it is extremely unlikely that they will infect their sexual partner."Fauci thought the international community's battle against the HIV/AIDS has gotten better over the last 30 years.Early on, when the disease was inaccurately thought to be a disease of developed world. There was a denial in many countries in Asia, in Southern Africa, South America and Caribbean, that this will turn out to be an extraordinary problem in those countries. As the years went by, it was clear that it was not a disease of gay men in the United States and the developed world. It was a disease mostly in the developing world when 90 percent of new infections occur in low- and middle-income countries and 67 percent of the cases are in Southern Africa."The response of the global community first was denial and not full appreciation of the potential impact of the pandemic. As the years have gone by, the response has been better and better," said Fauci, an immunologist that has made substantial contributions to research in the areas of AIDS and other immunodeficiencies, both as a scientist and as the head of NIAID.The advance in the arena of therapy with drugs has been " spectacular" and "very impressive", he said.In the early 1980 before there were any drugs, the median survival period of people in the United States who was infected with HIV, was about six to eight months. "Today in 2010, if someone was newly infected with HIV and he's 20-25 years old, and you put them on therapy, you can predict mathematically that they will live additional 50 years," said Fauci.Over the last couple of years, there has been "significant but slow" advances with vaccines against HIV. For example, there was a trial that was conducted in Thailand in which there was a modest degree of efficacy, about 31 percent of protection."That's not enough to have a vaccine available for widespread use but give us some important clues into what next generation of vaccines would be," said Fauci.As to the "three zeros" target adopted by the United Nations this year, Fauci said that it's "aspirational but not gonna be easy.""It is good to set very high goals for the future. I don't think that we realistically are gonna get to zero new infections, zero new discrimination, zero (AIDS-related) death in the next few years," said Fauci. "I think it will take several years to get there. I believe that if more countries and the international community are engaged to play a role in trying to stop HIV, to prevent and treat and care for HIV-infected individuals, that we will automatically achieve that objective."
BEIJING, Jan. 8 (Xinhua) -- China started the Spring Festival peak travel season Sunday, with tens of millions of passengers, mainly migrant workers and college students, on the move in the world's largest seasonal migration.The Spring Festival, or Chinese Lunar New Year, fall on Jan. 23 this year. It is the most important traditional Chinese festival for family reunions.A total of 3.16 billion passenger trips are expected during the 40-day peak travel season, or Chunyun (Spring transportation) in Chinese, up 9.1 percent from a year earlier, according to the National Development and Reform Commission.
WASHINGTON, Nov. 22 (Xinhua) -- Long-term coffee consumption may be associated with a reduced risk for endometrial cancer, according to a study published online Tuesday in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.Edward Giovannucci, professor of nutrition and epidemiology at the Harvard School of Public Health, said that coffee is emerging as a protective agent in cancers that are linked to obesity, estrogen and insulin."Coffee has already been shown to be protective against diabetes due to its effect on insulin," said Giovannucci, a senior researcher on the study. "So we hypothesized that we'd see a reduction in some cancers as well."The researchers observed cumulative coffee intake in relation to endometrial cancer in 67,470 women who enrolled in the Nurses' Health Study. During the course of 26 years of follow-up, researchers documented 672 cases of endometrial cancer.Drinking more than four cups of coffee per day was linked with a 25 percent reduced risk for endometrial cancer. Drinking between two and three cups per day was linked with a seven percent reduced risk.A similar link was seen in decaffeinated coffee, where drinking more than two cups per day was linked with a 22 percent reduced risk for endometrial cancer.Giovannucci said that he hopes this study will lead to further inquiries about the effect of coffee on cancer because in this and similar studies, coffee intake is self-selected and not randomized.