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Holidays will look different this year for many Americans, with dinners outside, social distancing, or passing on family gatherings altogether. But several companies developing rapid at-home COVID-19 tests are hopeful that won't be the case next year. The goal is to make inexpensive, easy-to-use COVID tests that can deliver results in minutes, just like a pregnancy test. "For people to feel comfortable to associate with friends or family, there needs to be a testing methodology ideally that can be performed at home," said Tony Lemmo, CEO of the manufacturing company BioDot.The company's technology is being used by over 70 manufacturers worldwide making COVID-19 antigen, antibody, and PCR tests. Their automated platforms dispense nanoliter/picoliter amounts of reagent onto the tests accurately and fast.Lemmo says just one of their systems can support the production of roughly 100 million COVID-19 tests per year, helping to make high-volume production possible.“We knew we were going to be called on by customers to manufacture more equipment to provide them the ability to manufacture more tests," said Lemmo. To meet customer demand, BioDot increased staffing and built a new facility, compressing production time from months to weeks. The FDA recently authorized the first rapid at-home test that can deliver results in 30 minutes, eliminating the need for a lab to test the sample. But the molecular single-use test will only be available to patients with a doctor's prescription who are suspected of being infected with COVID-19.Companies developing tests hope the FDA will soon authorize another at-home testing tool: the rapid antigen test.These inexpensive tests provide results within minutes, and companies developing them say millions could be sold without a doctor's referral.“From what we’re hearing, it’s really just a matter of possibly months before there’s at least sufficient data to be able to support an at-home use of a test like an antigen test," said Lemmo.Lemmo says if authorized by the FDA, manufacturers could make millions of these tests in a matter of months. But antigen tests are less accurate, and the FDA wants to ensure they'll be simple enough for people to use at home. There are also concerns over how the data will be reported to health authorities. “I think any at-home testing or massive rollout of a test into the communities needs to be done very carefully and with a lot of education around it," said Clinical Lab Director Melissa Miller. Dr. Miller is a professor of pathology and laboratory medicine at the University of North Carolina Chapel Hill and Medical Director for the Clinical Microbiology Lab for the Medical Center.She worries the inaccuracies of these tests could eventually lead the public to lose trust in all testing. “Even at 98 percent specificity, which is very, very high. That means you’re going to have a false positive two out of every 100. If you started testing a hundred million people, this is millions of people who have a false-positive test," said Dr. Miller. She says this could lead to healthy people isolating and missing work or school unnecessarily, and false-negative results could give people a false sense of security. “These rapid antigen tests were pushed out to skilled nursing facilities; this is a very high-risk patient population. This is actually where you want a very accurate test," said Dr. Miller. She says it’s unclear how well antigen tests detect the virus in asymptomatic patients but agrees more data is needed to figure that out.“It might make more sense for K-12 schools, or even college settings, where there’s less risk for a poor outcome if you have a false positive or a false negative," said Dr. Miller. But with a growing demand for convenient at-home testing, manufacturers are hopeful that in the months ahead, the FDA will soon open the door to new solutions. 3889

Google is releasing an updated version of its high-end Pixel phone packed with new camera tricks, a Chrome OS tablet and its first smart-screen device with Google Assistant.Put another way: Google is taking on the iPhone, the Surface Pro and the Echo Show.The company announced on Tuesday the new Pixel 3, Pixel Slate and Google Home Hub. All three are additions to its "Made for Google" lineup and were announced at a press event in New York City.The trio represent the latest update from Google's two-and-a-half-year-old hardware division, which is finally building a single, cohesive Google device brand."We've realized that if we wanted to push the envelope on innovation, we really needed to have a focused hardware effort," Rick Osterloh, Google's SVP of hardware, told CNN Business during an early look at the new products. "That meant combining the very best of Google's technology — our AI, our software and all of the hardware that we're building — to create a great user experience."The launch of a device with an always-on microphone and a camera comes at a critical time for the company. On Monday, Google acknowledged a previously undisclosed vulnerability that had to potential to expose Google+ accounts, but no evidence of a breach was found. 1267

Hold off on that funeral dirge for Macy's. The department store isn't dead yet.Macy's topped Wall Street's profit forecasts Tuesday and provided a healthy outlook for this year.The results strongly suggest there is still room for traditional stores in the mall in a world increasingly dominated by the likes of Amazon and Walmart.Macy's chairman and CEO Jeff Gennette said the company was "encouraged" by improvement at the company's brick-and-mortar stores and continued growth in online sales.Gennette said digital revenue posted a double-digit percentage increase for the 34th quarter in a row, a run of more than eight years.And the company is still investing heavily in its Bluemercury chain of specialty beauty stores and the discount outlet Backstage. Macy's said it opened 36 Bluemercury stores and 30 Backstage stores last year, even as it closed 16 Macy's stores.Gennette added during a conference call with analysts that Macy's plans to open 100 more Backstage locations this year, including in malls.Macy's is also selling real estate to shore up its balance sheet. The company said it raised 1 million last year and .3 billion over the past three years by getting rid of some stores, warehouses and parking garages.Macy's is also working with real estate company Brookfield Asset Management on other transactions.Macy's said Tuesday it is selling several floors in its State Street store in Chicago to a real estate fund backed by Brookfield for million. Brookfield plans to convert the floors into office space.All this is good news for Macy's. But one analyst said Macy's needs to do more before its turnaround qualifies as a true Miracle on 34th Street."There is a long tail of shops that look dated, are in sub-optimal locations, and where the customer experience is poor. Macy's must remedy this if it is to transform the business," Neil Saunders, managing director of GlobalData Retail, said in a report.Nonetheless, the real estate transactions and improved sales outlook are two reasons Wall Street has fallen in love with Macy's again.The stock surged nearly 12% in early trading before pulling back a bit. Macy's has soared more than 45% in the past six months.Department store chains Kohl's, Nordstrom and JCPenney — which will all report results later this week — rallied as well Tuesday. Another chain, Dillard's, rose 12% too after it also posted strong quarterly results.Investors are clearly betting that Macy's wasn't the only traditional retailer that had a happy holiday season. 2527

Having an adequate supply of personal protective equipment could have saved the state of California hundreds of millions of dollars and stopped roughly 18,000 essential workers from getting the coronavirus, according to a new study from the University of California Berkeley.Researchers at the school looked at the cost of PPE and the early costs and infection rates of coronavirus in California. They conclude with a recommendation that the state stockpile PPE for a future pandemic.The team’s first data point is based on supply and demand; purchasing PPE when it is not high in demand, then saving it for when it's needed. According to the study, the cost of purchasing the same amount of PPE when there was not a global demand would be 17 percent of what the projected cost is now during the pandemic.“Maintaining the stockpile would be cheaper than real-time purchases even if it was not needed for another 35 years, and even if we were fortunate enough to not need the stockpile for longer than that, it would be a highly financially prudent form of insurance,” the researchers stated.Between mid-March and mid-July, roughly 250,000 healthcare workers in California filed for unemployment benefits because there was not sufficient PPE for them to go to work.For each week those healthcare workers could not report to work, it cost the state million in unemployment benefits. The researchers conclude millions could be saved by having the personal protective equipment available.Looking at rates of infection and studies from Europe showing transmission rates at hospitals, Berkeley researches believe almost 18,000 coronavirus cases among essential workers could have been prevented with an adequate supply of PPE.“If those worker cases had been avoided, an estimated 3,030 secondary cases among household members could have also been avoided, thus totaling at least 20,860 cases that could have been averted,” the study states.A separate survey conducted in June and July asked California’s skilled nursing facility staff about equipment; more than 20 percent reported still having inadequate supplies of PPE, and 80 percent said they were very or extremely concerned about workplace infection.The Berkeley study also appears to give support to California Senate Bill 275 as amended in July 2020, that “would require the state to create a PPE stockpile sufficient to protect healthcare and other essential workers for at least 90-days of a future pandemic or health emergency.” 2496

Given the continued customer demand we expect over the coming months, we’ll be bringing on an additional 300,000 full-service shoppers to support cities nationwide. As more people look for immediate, flexible earnings opportunities during this time, we hope that Instacart can be an additional source of income for those looking to earn while also delivering for the communities in which they live. 406