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Linkin Park did not and does not endorse Trump, nor authorize his organization to use any of our music. A cease and desist has been issued.— LINKIN PARK (@linkinpark) July 19, 2020 188
LA JOLLA, Calif. (KGTV) -- Several hundred people peacefully marched in La Jolla Friday afternoon in support of the Black Lives Matter movement and to protest systemic racism.The group gathered at La Jolla Cove and then walked to Windansea Beach as they held white carnations to signify peace.It wasn't immediately clear how long the protest would be held.The protest is one of several local demonstrations that have been held in San Diego County over the last few weeks. Nationwide, demonstrations have been held, sparked by the death of George Floyd in Minneapolis while an officer held his knee on his neck for nearly 10 minutes. 640

Last year's seasonal flu vaccine effectiveness was just 42%, the US Centers for Disease Control and Prevention estimated. Even if vaccinated, then, people had inadequate protection against the flu.This limited effectiveness was due to a mutation that occurred in the influenza A (H3N2) vaccine strain, according to a new study published Monday in the journal Proceedings of the National Academy of Sciences. This vaccine mutation resulted from an egg-based manufacturing process commonly used today.This year's flu vaccine may also be imperfect, said Scott Hensley, author of the new study and an associate professor at the University of Pennsylvania. Add to that, he said, "this could end up being a pretty bad flu season."Still, he said, "our best protection" against severe illness is getting vaccinated with the flu shot we have today.Finding answersEach year before flu season begins, a vaccine is made based on whichever virus strains are expected to circulate. The selected seed strains are distributed to vaccine manufacturers which then produce their formulations and make them available to health care professionals before the season begins.During the 2015-16 season, vaccine effectiveness was 47%, while for the previous 2014-15 season, effectiveness was just 19%, according to the CDC. While the overall effectiveness of last season's vaccine was 42%, it was only 34% effective against the H3N2 viruses that dominated the season.Vaccine effectiveness varies based on how well it matches the circulating virus strains. Sometimes, a vaccine corresponds to the predominant virus yet its effectiveness is still not what scientists would expect. Trying to understand which element of the vaccine failed is difficult.Hensley and his team began their investigation of last year's vaccine by looking at the seed strains that had been distributed to vaccine manufacturers. These seed strains had been propagated in chicken eggs, the common method used today."The sequences of these viruses are available and when we did an alignment to see what the sequence of these vaccines were compared to the viruses that were circulating, it became very obvious that there was this mutation," said Hensley.To see the effects of the mutation, the team next looked at how the immune systems of both animals and humans who'd been inoculated with an egg-based flu vaccine responded to the actual circulating viruses.The antibodies -- immune system proteins that fight invading pathogens -- elicited in both animals and humans failed to bind to and neutralize the flu viruses, Hensley and his colleagues found.While most vaccines in the United States are made in chicken eggs, a small fraction are produced in insects or mammalian cells, Hensley explained. (These are given to people with egg allergies.) He and his team compared immune responses in animals and humans who had received a cell-based vaccine -- in this case, Flublok made by Protein Sciences Corporation."And we found both animals and humans receiving that (cell-based) vaccine had superior antibody responses that could bind and neutralize these circulating H3N2 strains," said Hensley.Making a better vaccine"Most of the infrastructure to produce vaccines in the US is based on chicken eggs," said Hensley. There are good reasons for this, including the fact that egg-based propagation allows manufacturers to quickly produce large quantities of vaccine.While egg adaptations have always been a problem, beginning last year it had become a "huge problem," said Hensley. "As soon as you try to grow this virus in eggs, within a few hours, the virus will acquire this kind of mutation."This is not an easy problem to fix, he said. To produce vaccines in cells means "a very expensive process for companies to just change their overall manufacturing process," Hensley explained. "You can't really do that on the drop of a dime."Meanwhile, the same seed strains used last year are being used this year to make the current vaccine, said Hensley."This year may be especially difficult because, in addition to this egg adaptive mutation which was present last year, there's indication that the H3N2 viruses are actually evolving," said Hensley.Not only will the vaccine be a mismatch with the actual circulating viruses due to egg adaptation but the vaccine could also be a mismatch due to unexpected viral evolution.What kind of flu season is ahead?It's too early to speculate which viruses will become dominant in the United States over the course of the coming flu season, said Hensley, "but it's starting to look like it will be H3 viruses." H3 viruses are influenza A viruses."There are the A group of viruses and the B groups," said Dr. William Schaffner, an infectious disease specialist at Vanderbilt University. "The A groups are the ones that usually are responsible for large epidemics ... whereas the B flu strains usually smolder along. They always cause illness -- it can be just as severe as the A strains -- but they don't produce large outbreaks."Though last year's vaccine was mostly ineffective in thwarting the flu, it still prevented nearly 30% of hospitalizations that might have resulted, according to CDC calculations. For older adults, that rate was even higher, at 37%. Plus, the vaccine reduced outpatient visits by 42% last season.The CDC advises everyone 6 months and older to get a flu shot, as only injectable flu vaccines are recommended. More than 130 million doses of flu vaccine have been distributed so far this year and flu activity is still low across the nation.It's still early days, but experts believe we may be facing a tough season, and not only because of vaccine concerns.The reason?Australia had a tough flu season this year, with a total of 215,280 laboratory-confirmed cases and 504 flu-associated deaths reported to its National Notifiable Diseases Surveillance System as of October 13, government data show. According to a surveillance system report, adults over the age of 80 and children between 5 and 9 years old have been most affected."In general, we get in our season what the Southern Hemisphere got in the season immediately preceding us," Dr. Anthony Fauci, director of the United States' National Institute of Allergy and Infectious Diseases, said in an interview last month.An "intelligent guess," therefore, is that the Northern Hemisphere, like the Southern Hemisphere, will likely battle more cases of the viral infection, he said, though "with influenza, it is never 100%.""If H3N2 viruses dominate the US flu season again this year, vaccine effectiveness will likely be moderate to low again," said Hensley.Still, he said, everyone should get their annual flu shot."The other components of the vaccine, like H1N1 and influenza B, will likely provide excellent protection," said Hensley. "The vaccine will also likely prevent severe disease and death caused by H3N2 viruses, even though this component of the vaccine is mismatched." 6969
LAKEWOOD, Ohio - Lizzie Ackerman loves to read."We found that it's really valuable and rewarding to learn about people that are different than us,” said Ackerman.When Ackerman thought about how she would get involved with the Black Lives Matter Movement, she knew just what to do."Sharing books about people who are different than we felt like a really good way to educate ourselves and our community just about the world around us,” she said.This Lakewood resident is starting her very own little free diverse library.It will work similarly to all the little free libraries we’ve seen across Northeast Ohio, except this one will only carry books from Black authors, feature Black people or educate folks on how to be anti-racist. It will also feature topics specific to the LGBTQ+ community, people with disabilities, and cultural, religious, and ethnic minorities."Reading about people and experiences and lifestyles and cultures that are different than your own just helps cultivate empathy and respect and compassion and understanding,” said Ackerman.Ackerman is joining a national movement started by a New York City school counselor."In the wake of George Floyd’s murder, I really thought it would be important to use libraries as an outlet and as a vessel to get important stories heard and read by others within the community,” said Sarah Kamya.Kamya started what she calls the 'Little Free Diverse Libraries Project.’She's collected thousands of books and shipped them to people in all 50 states wanting to start little diverse libraries of their own."Once you put a book in, you don’t know where it goes so I just imagine the little Black or brown child picking up a book and seeing themselves represented or the white parent who is educating themselves, learning more about cultures and learning more how to walk alongside others and people that don’t look like them,” said Kamya.Ackerman plans to launch her library in the middle of the month but she needs some help, so she’s started a Go Fund Me page."Normally little free libraries are stocked by people in the community and just whatever book they’re done with, but because we have a specific topic, we’d like to make sure that we always have books on hand that are relevant,” said Ackerman.Ackerman says this is an opportunity to amplify all Black people through the pages of these books.“It's really important that everyone see themselves reflected and celebrated in literature,” she said.This story was first reported by Amanda VanAllen at WEWS in Cleveland, Ohio. 2541
Liliana Gallegos says she could not breathe and had chest pains when she was infected with the novel coronavirus.“Back then, even myself, I wasn’t masking up,” Liliana Gallegos said. “I was like, ‘it’s not that serious. It was like a cold or flu.’”It was far from a cold or flu. Gallegos was diagnosed with COVID-19 in April, and she wasn’t the only one in her household. Her 63-year-old father and her children also got infected. Later, her fiancé got sick.“He passed it on, and all his co-workers caught COVID. It just spread, and we were not cautious about that at that time,” said Gallegos.Gallegos recovered 17 days later. The experience gave her a new perspective.“I think it’s so important to take the precautions they are telling us. Six feet apart, sanitize, wear your mask,” she said.More than 1,000 hospitals in the U.S. are teaming up to encourage everyone to stay safe.The Every Mask Up (#EveryMaskUp) campaign provides vital health resources and has developed messages on a variety of digital platforms to get the word out.Medical experts say wearing a mask is the best chance of slowing the COVID-19 pandemic.Right now, more than 13 million Americans are infected, and more than 250,000 have died. 1220
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