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TIANJIN, April 16 (Xinhua) -- As China tries to establish a universal medicare umbrella, its first move to offer treatment to all the hemophilia patients in the country is to know their population and where they are.China's national hemophilia information management center registered 7,980 cases nationwide since its establishment last year in a bid to provide reference for making national treatment policies and medicine production quota, said the center officials Saturday.Yang Renchi with the center and the Chinese Academy of Medical Sciences, said that the patient information database will help the government make hemophilia-related medical and social welfare policies, optimize resources and guide the manufacturing of drugs such as coagulation factor VIII.The information center, created by the Ministry of Health, is located in the Blood Diseases Hospital of the Chinese Academy of Medical Sciences in the port city Tianjin in north China.Hemophilia is a rare genetic bleeding disorder that prevents the blood from clotting properly, resulting in easy bruising and prolonged bleeding from trauma. Lack of treatment can lead to permanent disabilities or even death.China is estimated to have roughly 100,000 hemophilia patients."Be inspired; get involved in Treatment for All" is the theme for the 22nd World Hemophilia Day, which falls on Sunday, April 17."A necessary precondition for 'Treatment for All' is to know the clinical information and location of each case," said Yang, "and this is exactly what the information system does."In addition, China plans to establish hospital-based provincial hemophilia management centers within five years across the country to register and monitor patients and standardize disease diagnosis and treatment under the information system.SHORTAGE OF DRUGSBlood-derived coagulation factor VIII and recombinant coagulation factor VIII are two effective drugs which are vital for hemophiliacs. However, the drugs are expensive and produced in limited quantities, a difficulty which hundreds of thousands of hemophiliacs in China have to confront.According to Yang, the minimum dose of coagulation factor VIII for prevention of bleeding episodes is two international units (IU) per kg of weight a day. A 50-kg hemophilia patient needs at least 36,500 IU of factor VIII every year to prevent bleeding."Each IU of blood-derived coagulation factor VIII costs about 3 yuan(0.46 U.S. dollars) and the annual cost is almost 120,000 yuan. The recombinant one is almost twice the price," said Yang.Only four drug firms are qualified to manufacture blood-derived coagulation factor VIII in China. The national output in 2010 was 400,000 vials (200 IU per vial) which means 80 million IU for the entire country.Wu Runhui, a hematology specialist with the Beijing Children's Hospital, said that the minimum dose is only for the prevention of bleeding episodes which are required to keep the patient alive. For the hemophiliac to live a regular lifestyle, 3,000 IU per kilo a year is needed, which would cost half a million yuan a year."Even in the most developed countries, a hemophiliac cannot survive without supportive medical policies and social welfare system," said Wu.
WASHINGTON, April 3 (Xinhua) -- In the largest study of its kind, researchers from a consortium led by the University of Pennsylvania School of Medicine, the University of Miami, and the Boston University School of Medicine, identified four new genes linked to Alzheimer's disease. The findings appeared Sunday in the current issue of Nature Genetics.Each gene individually adds to the risk of having this common form of dementia later in life. These new genes offer a portal into what causes Alzheimer's disease and is a major advance in the field.The study, conducted by the Alzheimer's Disease Genetics Consortium, reports genetic analysis of more than 11,000 people with Alzheimer's disease and a nearly equal number of elderly people who have no symptoms of dementia. Three other consortia contributed confirming data from additional people, bringing the total number of people analyzed to over 54,000. The consortium also contributed to the identification of a fifth gene reported by other groups of investigators from the United States, the United Kingdom, France, and other European countries.The study is the result of a large collaborative effort with investigators from 44 universities and research institutions in the United States, led by Gerard Schellenberg at University of Pennsylvania."This is the culmination of years of work on Alzheimer's disease by a large number of scientists, yet it is just the beginning in defining how genes influence memory and intellectual function as we age. We are all tremendously excited by our progress so far, but much remains to be done, both in understanding the genetics and in defining how these genes influence the disease process," Schellenberg said.Until recently, only four genes associated with late-onset Alzheimer's have been confirmed, with the gene for apolipoprotein E-e4, APOE-e4, having the largest effect on risk. The Nature Genetics studies add another four -- MS4A, CD2AP, CD33, and EPHA1 -- and contribute to identifying and confirming two other genes, BIN1 and ABCA7, thereby doubling the number of genes known to contribute Alzheimer's disease.

SAN FRANCISCO, May 3 (Xinhua) -- Apple Inc. announced on Tuesday that it has updated its iMac all-in-one desktop, adding Intel's next generation quad-core processors, Thunderbolt data ports and a new HD camera.Starting at 1,199 U.S. dollars, the new iMac is up to 70 percent faster and its new graphics deliver up to three times the performance of the previous generation, Apple said in a statement.The new iMac features quad-core Intel Core i5 processors with an upgrade option to Core i7 processors.The 21.5-inch model has a single Thunderbolt port while the 27- inch has two, in addition to four USB 2.0 inputs and a FireWire 800 port.Thunderbolt, which debuted with Apple's updated MacBook Pro notebooks in February, is also an Intel design bringing together high-speed data transfer and high-definition display onto a single cable. It can transfer a full-length HD movie in less than 30 seconds with a speed of 10 gigabits per second, which is twice the speed of USB 3.0, 12 times faster than FireWire 800 and up to 20 times faster than USB 2.0.The new iMac also includes a built-in FaceTime HD camera, which supports high-definition video calls, Apple said.
LOS ANGELES, May 6 (Xinhua) -- Limiting prolonged bottle use in children may be an effective way to help prevent obesity, a new study suggests.For the study, researchers from the Center for Obesity Research and Education at Temple University (CORETU) and the Ohio State University College of Public Health analyzed data from 6,750 children to estimate the association between bottle use at 24 months of age and the risk of obesity at 5.5 years of age, according to the Science Daily on Friday.Of the children studied, 22 percent were prolonged bottle users, meaning that at two years of age they used a bottle as their primary drink container and/or were put to bed with a calorie- containing bottle.The findings showed that nearly 23 percent of the prolonged bottle users were obese by the time they were 5.5 years old."Children who were still using a bottle at 24 months were approximately 30 percent more likely to be obese at 5.5 years, even after accounting for other factors such as the mother's weight, the child's birth weight, and feeding practices during infancy," said Dr. Robert Whitaker at CORETU, lead author of the study.Drinking from a bottle beyond infancy may contribute to obesity by encouraging the child to consume too many calories, the researchers noted."A 24-month-old girl of average weight and height who is put to bed with an eight-ounce bottle of whole milk would receive approximately 12 percent of her daily caloric needs from that bottle," explained co-author Rachel Gooze.Gooze noted that weaning children from the bottle by the time they are one year of age is unlikely to cause harm and may prevent obesity. The authors suggested that pediatricians and other health professionals work with parents to find acceptable solutions for stopping bottle use at the child's first birthday.The findings adds new evidence to the theory that obesity prevention should begin before children enter school, the researchers said.
SAN FRANCISCO, March 23 (Xinhua) -- Yahoo Inc. on Wednesday introduced a new feature to its search engine, which the company said can deliver answers and direct access to websites before users complete their query or hit the search button.The new feature, called Search Direct, predicts search results as fast as a person types and presents those results dynamically, Yahoo said."With today's launch, direct answers -- not the search results page -- is the primary focus. We are redefining the search process and prominently displaying direct answers where search decisions are being made," Shashi Seth, Yahoo's senior vice president of search and marketplaces, said in a statement."Search Direct is evidence of Yahoo continuing to lead innovation in search, enabling people to take action faster, find what is most important, and sample what is possible with the next stage of search technology," he added.Yahoo announced that Search Direct is rolling out in a public test version to its users across the United States Wednesday, and will be available in other Yahoo products and markets later this year.
来源:资阳报