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I’m profoundly grateful for the love and support from my family and friends.Thank you for your prayers and well wishes. And, while I have you, please remember to go vote. Because we are all in this together. https://t.co/6sAU4MYixlLove, Jeff— Jeff Bridges (@TheJeffBridges) October 20, 2020 299

Immunotherapy has gained ground against a stubborn opponent: ovarian cancer. A personalized cancer vaccine is safe and may lengthen the lives of ovarian cancer patients, a small clinical trial found.The research, published Wednesday in the journal Science Translational Medicine, showed "significantly higher" overall survival at two years among patients who received the vaccine, compared with patients who did not.Ovarian cancer is a "silent killer" because often it goes unnoticed until it is diagnosed at a late stage. Treated with surgery followed by chemotherapy, most patients -- 85% -- relapse and ultimately develop resistance to the chemo. At this point, they run out of treatment options.Still, scientists are hopeful based on the fact that a subset of patients shows an immune response to their cancer. Generally, these patients have better survival rates than those whose immune systems don't react in the same way.A vaccine, then, might be able to trigger and boost the immune system and increase the survival rates of patients, said Dr. Lana Kandalaft, senior author of the new study and an adjunct assistant professor at the University of Pennsylvania Perelman School of Medicine.  1210

If you have an old car seat, Target is looking to take them at their car seat trade-in event this monthBeginning Sept. 13, consumers will be able to go to any participating Target and exchange old car seats for a 20% off coupon.The event ends Sept. 26.Any car seat will be accepted, Target said.The company says the coupon can be used on a new car seat, stroller, or select baby gear item.The way it'll work is that customers will drop the car seat off in the designated box outside the store and then open the Target App and scan the code on the box.The coupon will appear in your wallet in the Target App, under "extra offers."You'll redeem your voucher by clicking the green checkmark next to the offer when you order online. If at the store, you'll scan your barcode at the register. 795

If you weren't able to make it to the failed Fyre Festival, the U.S. Marshals are making it possible for you to own a piece of merchandise from the botched 2017 music festival.Consumers will be able to purchase t-shirts, baseball caps, and other merchandise online through the U.S. Marshals' auctioneer, Gaston & Sheehan. 333

Hurricane Lane may have passed by the island chain over the weekend, but Hawaii is still feeling the storm's aftereffects as residents recover from days of heavy rain and remain on the lookout for even more showers.Lane dropped 52.02 inches of rain on Hawaii from August 22-26, the second highest rainfall total from a tropical cyclone in the US since 1950, according to preliminary data from the National Weather Service (NWS).That's behind only the 60.58 inches dumped on Nederland, Texas by Hurricane Harvey last year.Hawaii's Big Island -- the easternmost island in the chain -- was hammered hardest by rain. Some residents there had to be evacuated, with water rescues occurring in Hilo and Keaau, the NWS said. A number of roads were closed by flooding and landslides. 782