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SAN DIEGO (KGTV) - Locals are in for some sweet summer fun this year, as the San Diego County Fair returns to the Del Mar Fairgrounds.The fair, running from June 1 - July 4, is bringing some "kid-in-a-candy-store" wonder to Del Mar this year with its theme "How Sweet it is." Fair-goers will have opportunities around every corner to satisfy their sweet tooth, from creative confections to nature's fruits.San Diego's fair routinely sees more than a million locals and tourists pass through during its month-long run, with more than 4,000 attractions, and nearly 2,000 concerts — so San Diegans have plenty of chances to find some fun. WHEN & WHERE...June 2 - July 4 at the Del Mar Fairgrounds, 2260 Jimmy Durante Blvd., Del Mar. TICKETS...There are plenty of deals to check out for select days, concerts, and promotions at the fair. For regular admission:Kids ages 5 and younger: FreeKids ages 6- to 12-years-old: Adults ages 13- to 61-years-old: Seniors ages 62 and older: Season pass for all 26 days: MORE: Deals on SD Fair admission, food, and rides GETTING THERE & PARKING...If you're heading to the fair, plan to park on-site or off-site ahead of time. Real-time parking updates can also be found on AM 1680 during the fair's run.General parking: Preferred parking: Parking lots will open at 8 a.m. on weekend and July 2-4, and 9 a.m. on weekdays. Lots close an hour after the fair closes. Tram service will run continuously from fairgrounds lots.Public transportation can also be taken on NCTD lines of The Coaster, The Sprinter, or Breeze Route 408; the MTS bus system or trolley Blue, Orange, and Green lines; and via Amtrak's Pacific Surfliner.MORE: Getting to and parking at the SD Fair WHAT TO SEE...There are countless things to check out during the fair's run.Concerts planned throughout the month are bringing some heavy hitter from the music world to San Diego, including Kansas, Sugarland, Hanson, Capital Cities, Barenaked Ladies, and many others.Comedy is also taking center stage, with performances by Larry the Cable Guy, Gabriel Iqlesias, and Jeff Ross.Of course, fan-favorite shows featuring local livestock (the Swifty Swine Racing Pigs!), local artists specializing in everything from painting to woodcarving to gems, and competitions (who's ready for an ol' fashioned watermelon seed spitting contest?) are set to return.A full calendar of events big and small is available to check out on the fair's website.MORE: San Diego Fair concerts line up big music, comedy acts 2569

SAN DIEGO (KGTV) — It's always a good time to check on supplies and make sure you and your family are prepared for an earthquake.The County of San Diego recommends seven simple steps for earthquake safety:Fix potential hazards, like areas of your home that could pose a danger during an earthquake;Create a disaster plan with your family. The county's tips on how to handle a disaster here;Create a disaster supplies kit. The county also has tips on what to pack here;Fix your building's potential weaknesses;During earthquakes and aftershocks: Drop, Cover, and Hold-On;After the earthquake, check for injuries and damage; andWhen safe, continue to follow your disaster planSan Diego County recommends packing enough water, food, and supplies to last each member of the family at least three days. They also recommend that families practice their disaster plan so they're ready when an emergency happens.When an earthquake does happen, families should drop, find cover under something sturdy, and hold on to that cover. If there isn't anything sturdy, find an interior wall that is not near any heavy furniture or glass, scoot down and cover your head.If outside, find an open area away from buildings, trees, or anything overhead such as utility wires, sit down, and cover your head.While San Diego County has sparse earthquake activity compared to the rest of the state, one big enough can send tremors into our region.Residents can also sing up for AlertSanDiego mobile alerts from the county. Residents can also dial 2-1-1 for emergency updates. 1557

SAN DIEGO (KGTV) - Mariah Sunshine Coogan's family says she lived up to her middle name. "She would walk into a room, and she would just light it up," her mother, Stacey Coogan, told 10News. The 23-year-old died Monday night when a plane carrying her and six others crashed in Scottsdale, Arizona. The Piper PA24 plane crashed at around 8:45 p.m. local time, shortly after it took off from the Scottsdale Airport.RELATED:  445

SAN DIEGO (KGTV) -- It’s back to school for many kids across San Diego County. For some, it means new anxieties in the classroom, but for others, it means facing their old foe: bullying. A new program aimed at helping students understand their emotions in an effort to stop aggressive behavior before it starts is sweeping through the San Ysidro School District. RELATED: New program tackles behavioral issues to reduce future crime and violence in school 464

SAN DIEGO (KGTV) — In some of the most severe cases of COVID-19, doctors are finding it’s not the coronavirus making people critically ill.It’s their own immune system, and a San Diego-based biotech company thinks it has an answer.La Jolla-based INmune Bio announced Tuesday it has FDA approval to begin a Phase 2 clinical trial on its inflammation fighting drug, Quellor.In many of the sickest COVID patients, doctors have noticed their blood is filled with high levels of immune proteins called cytokines. Cytokines act as messengers between cells and the virus can cause them to go haywire, setting off what’s known as a cytokine storm.In a cytokine storm, the body’s immune system starts to attack its own cells and tissues rather than the virus. During the Spanish Flu of 1918, many of the deaths were caused by cytokine storms.“You need to control the cytokine storm to keep patients from getting sick,” said INmune Bio’s CEO Dr. R.J. Tesi.There are several different types of cytokines. A drug undergoing testing in a federal trial with remdesivir targets a cytokine called beta interferon.The San Diego biotech’s drug Quellor suppresses a very specific cytokine called soluble tumor necrosis factor, which Dr. Tesi calls “the master cytokine” because of its role in triggering other immune proteins.Dr. Tesi said this particular cytokine may contribute to another troubling issue with COVID-19: blood clotting.“When they write the history of COVID-19, the clots are going to be the bad guy,” Dr. Tesi said. “These blood clots go off everywhere and they gum up the works. They make it so the lungs can't work. They make it so the kidneys can't work. They make it so the heart is screwed up. Make it so you have strokes.”INmune Bio, which is publicly traded but has just six full-time employees, is hoping its drug can address both the blood clots and the inflammation.The company plans to enroll 366 hospitalized COVID-19 patients for a Phase 2 trial to see if intervention with Quellor can keep people off ventilators and out of the ICU. 2053

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