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At least 285 U.S. children have developed a serious inflammatory condition linked to the coronavirus and while most recovered, the potential for long-term or permanent damage is unknown, two new studies suggest.The papers, published online Monday in the New England Journal of Medicine, provide the fullest report yet on the condition.The condition is known as multisystem inflammatory syndrome in children. It is considered uncommon and deaths are rare; six children died among the 285 in the new studies.Including cases in Europe, where it was first reported, about 1,000 children worldwide have been affected, a journal editorial said.The federal Centers for Disease Control and Prevention’s case definition includes current or recent COVID-19 infection or exposure to the virus; a fever of at least 100.4 for at least 24 hours; severe illness requiring hospitalization; inflammatory markers in blood tests, and evidence of problems affecting at least two organs that could include the heart, kidneys, lungs, skin or other nervous system.Digestive symptoms including nausea and diarrhea are common. Some children may have symptoms resembling Kawasaki disease, a rare condition in children that can cause swelling and heart problems.At least 35 states have had cases, and they seem to crop up a few weeks after local COVID-19 activity peaks, said Dr. Adrienne Randolph of Boston Children’s Hospital. She is a lead researcher for a multistate study that includes CDC scientists. The second paper involved 99 children in New York state, where the first U.S. cases occurred.Combined, the papers show 285 cases from March thru mid to late May but Randolph said additional U.S. children have been diagnosed in June.Most had current or recent COVID-19 infections but had previously been healthy.About 80% of children in the multistate study had heart-related problems, which included coronary aneurysms — a bulge in a heart artery that can be fatal.“Those need to be followed up,” Randolph said. “This is a life-threatening concern for a lot of patients.”Most affected children had no other health condition but about 30% were obese. The condition also appears to disproportionately affect Latino and Black children and boys.The average age was 8 years old. Researchers don’t know if adults can be affected.___Follow AP Medical Writer Lindsey Tanner at @LindseyTanner.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. (hyperlink ‘support’ with this: http://bit.ly/2ptoKnW 2618
Authorities in India have decided to hold off retrieving the body of the American national feared killed on North Sentinel Island amid concerns about a possible confrontation with the tribe that lives there.John Allen Chau is believed to have been killed by Sentinelese tribespeople after he visited their island home in the Andaman and Nicobar archipelago in November, breaching local laws strictly prohibiting contact with the isolated people.Indian police say Chau found local fishermen who agreed to take him near the island, before using a canoe the rest of the way. Days later, the fishermen -- who have since been arrested for facilitating his trip -- say they saw the tribespeople dragging his body around the island."We want to avoid direct confrontation with the tribespeople," Dependra Pathak, director general of police of the Andaman and Nicobar islands, told CNN when asked about the latest efforts to retrieve Chau's body. "We do not want to go there and create an unhappy situation."The decision to avoid a direct confrontation with the isolated tribe came after a series of meetings and reconnaissance trips made by the officials. Anthropologists and tribal experts were also consulted.By Sunday, authorities had mapped out the area with the help of the fishermen and observed several members of the tribe walking around the area where eyewitnesses claim to have seen Chau's body dragged and buried.However, despite ruling out any immediate attempts to land on the island, local police would not categorically rule out retrieving the body at a future date. "We are working on it. We'll firm up a plan very soon," said Pathak. 1660

BALTIMORE — A doctor described as providing care to the "sickest patients" in Baltimore died of COVID-19, Mercy Medical Center said in a Facebook post.Dr. Joseph J. Costa, the chief of critical care at the hospital, was 56 years old."Joe was more than a trusted colleague; he was also a true friend to many. He dedicated his life and career to caring for the sickest patients. And when the global pandemic came down upon us, Joe selflessly continued his work on the front lines—deeply committed to serving our patients and our City during this time of great need. His memory will live on as an example to us all," the hospital said in a Facebook post.Costa joined Mercy in 1997 and became Chief of Critical Care in 2005. From 2010 to 2016 he served as an officer of the Mercy Medical Staff, culminating with his 2-year tenure as President of the Medical Staff."Joe was admired and respected among providers throughout the Baltimore region for his clinical expertise. He was beloved by his patients and their family members—known for his warm and comforting bedside manner as well as his direct and informative communication style. When he counseled our patients and families, he did so with great compassion and empathy. For all the nurses and staff who worked closely with Joe on the Intensive Care Unit, he was like an older brother that all admired and revered," the post continued.Read the full letter below. Dear Friends of Mercy, It is with great sadness that we mourn the loss of Joseph J. Costa, M.D., Chief, Division of...Posted by Mercy Medical Center, Baltimore, MD on Saturday, July 25, 2020 This story was originally published by Brandon Ingram on WMAR in Baltimore. 1702
As more people turn to ketamine infusions to treat depression, researchers issue a new warning, comparing the drug to opioids.The infusions are offered at clinics located across the country. Scientists believe ketamine may treat symptoms of depression by blocking receptors on the brain.At Florida’s Ketamine Health Centers, clinical director May Nunez says they've seen an 85 percent success rate.“A lot of our patients come in, and they are highly suicidal. They are very treatment resistant,” explains Nunez. “They're experiencing high levels of depression. They have one infusion administered, and they come out. I'm basically looking at those symptoms are gone.”But new research from Stanford University is raising questions about using the drug over a long period of time.When patients in the study took an opioid blocker, researchers said their symptoms didn't improve, suggesting ketamine has to activate opioid receptors before treating depression.Researchers say that doesn't mean you shouldn't use ketamine, but instead, that more studies need to be done to fully understand ketamine before it's widely used in the long-term.Nunez says the side effects she's seen have been minimal.“So, what I always tell the patients is, you know, you're not going to get worse,” says Nunez. “You're either going to be in remission, sore or you're simply not going to respond.” 1386
BALTIMORE — Americans stepped up their home purchases in June by a robust 20.7% after the pandemic had caused sales to crater in the prior three months. But the housing market could struggle to rebound further in the face of the resurgent viral outbreak and a shrinking supply of homes for sale. Sales of existing homes rose last month to a seasonally adjusted annual rate of 4.72 million, the National Association of Realtors said. Their data showed all four regions of the country saw growth, with the west experiencing a larger increase. The data included single-family homes, townhomes, condominiums and co-ops. Despite the sharp monthly gain, purchases are still down 11.3% from a year ago, when homes had sold at an annual pace of 5.32 million.Inventory remains an issues, according to the National Association of Realtors (NAR). A low number of available homes was an issue before the pandemic. Total inventory is down 18.2 percent from a year ago, according to the data. The low supply and increasing demand could cause a spike in the price of homes.“Home prices rose during the lockdown and could rise even further due to heavy buyer competition and a significant shortage of supply," said Lawrence Yun, NAR’s chief economist.The median price for exisiting-home sales in June was 3.5 percent higher than a year ago. This is an ongoing trend, NAR says the median price has increased each of the last 100 months. 1428
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