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ATLANTA, Ga. – For more than six decades, Manuel’s Tavern has been the spot in Atlanta for people who love politics.“The quintessential political bar,” said Angelo Fuster, who knew the tavern’s original owner, Manuel Maloof, who got into politics himself decades ago. “Every election, we've been here. It is a place that a lot of people here gravitate to.”Folks will be there again on January 5, because the nation’s political attention is now zeroing in on Georgia, where the fate of the U.S. Senate hangs in the balance.Georgia isn’t exactly used to all this attention. The state has reliably been a Republican stronghold for decades. In 2020, though, it’s emerged as the last of the battleground states, with the final two Senate races of this election cycle.In one race, incumbent Republican Sen. David Perdue faces Democratic challenger Jon Ossoff. In the second race, incumbent Republican Sen. Kelly Loeffler faces Democratic challenger Raphael Warnock.“For all those Georgians who are tired of the campaign ads, of their mailboxes being flooded with advertisements from campaigns as well -- get used to it,” said Bernard Fraga, an associate professor of political science at Emory University in Atlanta.Fraga said both major political parties will be throwing their efforts into the two Senate races.“We're gonna have another two months of both sides, the Democratic and Republican candidates, but also the national parties, nonprofit organizations, mobilization groups, working their hardest to make sure that their campaigns win and that voters are active and engaged,” Fraga said.Craig Eberhart is with Men of Higher Standards, a nonpartisan, African American men’s group, focusing on voter registration in Georgia.“It’s gonna be bananas,” Eberhart said.People who live in Georgia can still register to vote through the first week of December. Eberhart believes the state is ready for its place as a battleground state.“For the forthcoming future, Georgia is going to be one of those states that you can't take for granted, you don't have in your back pocket,” Eberhart said. “You're going to have to work to get the vote of the people in Georgia.”Back at Manuel’s Tavern, Angelo Fuster wonders if this runoff might be different from those in years past.“We don't have a real good record of turning out for runoffs,” Fuster said. “I think that there's that energy.”Energy left because the sun hasn’t set on the 2020 elections quite yet. 2454

As the COVID-19 pandemic progresses, researchers say it is important to track how the coronavirus mutates because it could affect the efficacy of a vaccine.Like all living cells, viruses evolve their chemical make-up changes. In viruses like the flu, that happens frequently, which is why every year there is a new vaccine to treat whatever strain is expected to circulate. With COVID-19, however, those mutations happen much slower, according to research out of Arizona State University.“One of the things we’re still keeping an eye on is the evolution of this virus because that virus is still around in the community,” said Dr. Efrem Lim, an assistant professor at ASU. “Everyone is coming in blind to this. This is a novel virus. This isn’t something we have seen before.”In March, Arizona State University played host to our country’s fourth COVID-19 case. As soon as it was detected, Dr. Lim started studying how the virus mutates and sent his findings to the World Health Organization. It's something that still continues to this day.“This virus, overall, mutates pretty slowly, which is a good thing,” said Dr. Lim. “However, we can have instances where the virus can have very large, dramatic, mutations, such as deletions in the genome.”While rare, Dr. Lim says those mutations can be significant as it changes how the virus acts inside the body.Currently, scientists are focusing much of their efforts on identifying ways to eliminate the function of the spike protein in COVID-19, as it is the way the virus binds to our cells and infects them (spike proteins are the stalks that protrude from the center of the virus that make it so recognizable).“It is very good news that the virus is not changing rapidly,” said ASU virologist Dr. Brenda Hogue. “We will have to see over time, as the virus continues to circulate, as we put a vaccine into play, whether or not there will be any issues.”Dr. Lim says right now there does not appear to be any issues because the virus mutates slowly, but he adds it could adapt to a vaccine once one begins to circulate.He says more testing needs to be done to determine that, however. 2140

Average rates on long-term mortgages continue to fall to new record lows, as the key 30-year loan dropped below 3% for the first time in 50 years. The stagnant economic recovery in the face of the coronavirus pandemic is keeping inflation tamped down despite pent-up homebuying demand. Mortgage buyer Freddie Mac says the average rate on the 30-year home loan fell this week to 2.98% from 3.03% last week. These are the lowest levels since Freddie Mac began tracking averages in 1971. The rate averaged 3.81% a year ago.In their update, Freddie Mac says the low rates has led to increased homebuyer demand. Meanwhile, according to the Mortgage Bankers Association, refinancing applications increased recently, about 12 percent in the last week. However, Freddie Mac warns that with an increase in coronavirus cases, the economy can stagnate and cause temporary job layoffs to possibly become permanent. The average rate on the 15-year fixed-rate mortgage declined to 2.48% from 2.51%, from last week. 1008

At least 285 U.S. children have developed a serious inflammatory condition linked to the coronavirus and while most recovered, the potential for long-term or permanent damage is unknown, two new studies suggest.The papers, published online Monday in the New England Journal of Medicine, provide the fullest report yet on the condition.The condition is known as multisystem inflammatory syndrome in children. It is considered uncommon and deaths are rare; six children died among the 285 in the new studies.Including cases in Europe, where it was first reported, about 1,000 children worldwide have been affected, a journal editorial said.The federal Centers for Disease Control and Prevention’s case definition includes current or recent COVID-19 infection or exposure to the virus; a fever of at least 100.4 for at least 24 hours; severe illness requiring hospitalization; inflammatory markers in blood tests, and evidence of problems affecting at least two organs that could include the heart, kidneys, lungs, skin or other nervous system.Digestive symptoms including nausea and diarrhea are common. Some children may have symptoms resembling Kawasaki disease, a rare condition in children that can cause swelling and heart problems.At least 35 states have had cases, and they seem to crop up a few weeks after local COVID-19 activity peaks, said Dr. Adrienne Randolph of Boston Children’s Hospital. She is a lead researcher for a multistate study that includes CDC scientists. The second paper involved 99 children in New York state, where the first U.S. cases occurred.Combined, the papers show 285 cases from March thru mid to late May but Randolph said additional U.S. children have been diagnosed in June.Most had current or recent COVID-19 infections but had previously been healthy.About 80% of children in the multistate study had heart-related problems, which included coronary aneurysms — a bulge in a heart artery that can be fatal.“Those need to be followed up,” Randolph said. “This is a life-threatening concern for a lot of patients.”Most affected children had no other health condition but about 30% were obese. The condition also appears to disproportionately affect Latino and Black children and boys.The average age was 8 years old. Researchers don’t know if adults can be affected.___Follow AP Medical Writer Lindsey Tanner at @LindseyTanner.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. (hyperlink ‘support’ with this: http://bit.ly/2ptoKnW 2618

As New Haven, Connecticut, Fire Chief John Alston Jr. spoke to reporters about a spate of drug overdoses on Wednesday, he heard shouting coming from behind him."We're getting another call of a person," Alston said.He quickly helped coordinate the response, and then returned to the microphone.That scene came on the same day that as many as 40 people in the area of New Haven Green were believed to have overdosed on some form of K2 that may have been laced with opioids, according to New Haven police spokesman Officer David Hartman.New Haven Green is a large park and recreation area in the city's downtown.The patients included people of various ages and demographics, Alston said."It's a nationwide problem. Let's address it that way," he said. "It's a nationwide problem that people are self-medicating for several different reasons, and every agency -- police, fire, medical hospitals -- all are strained at this time. This is a problem that's not going away."New Haven police said one person is in custody.Director of Emergency Operations for New Haven Rick Fontana said the patients had symptoms of increased heart rates, decreased respiratory rates and a lot of vomiting. Some people were unconscious, others were semi-conscious.No one has died, but two individuals are considered to be in serious, life-threatening condition. Some individuals who were released from the hospital needed to be treated a second time for an additional apparent overdose, Fontana said.K2 is a synthetic cannabinoid related to marijuana that is frequently laced with other drugs, said Dr. Sandy Bogucki of the Yale School of Public Health.In two cases, Narcan was not effective in the field, but a high dose of Narcan at the hospital was effective in combating the overdose effects. Because of that, authorities believe there was some form of opioid or synthetic fentanyl involved in the substance.The response from emergency responders has been "tremendous," Fontana said.He said authorities have been treating and sometimes transporting six or seven people at one time and the actions of first responders have been "lifesaving." 2131

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